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中国医学科学院 北京... [6]
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期刊论文 [31]
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浏览/检索结果:
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Blood tau-PT217 contributes to the anesthesia/surgery-induced delirium-like behavior in aged mice
期刊论文
ALZHEIMERS & DEMENTIA, 2023, 页码: 17
作者:
Lu, Jing
;
Liang, Feng
;
Bai, Ping
;
Liu, Chenghao
;
Xu, Miao
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/11/17
anesthesia
delirium
phosphorylated tau at threonine 217
surgery
tau
tau phosphorylation
Microglia-derived TNF-alpha mediates endothelial necroptosis aggravating blood brain-barrier disruption after ischemic stroke
期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 18
作者:
Chen, An-Qi
;
Fang, Zhi
;
Chen, Xiao-Lu
;
Yang, Shuai
;
Zhou, Yi-Fan
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2019/10/14
Effects of irisin on the dysfunction of blood-brain barrier in rats after focal cerebral ischemia/reperfusion
期刊论文
BRAIN AND BEHAVIOR, 2019, 卷号: 9, 期号: 10
作者:
Guo, Peipei
;
Jin, Zhao
;
Wu, Huisheng
;
Li, Xinyi
;
Ke, Jianjuan
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/12/05
blood-brain barrier
cerebral ischemia
reperfusion
irisin
matrix metalloproteinase-9
Quercetin improves blood-brain barrier dysfunction in rats with cerebral ischemia reperfusion via Wnt signaling pathway
期刊论文
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2019, 卷号: 11, 期号: 8
作者:
Jin, Zhao
;
Ke, Jianjuan
;
Guo, Peipei
;
Wang, Yanlin
;
Wu, Huisheng
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/05
Quercetin
blood-brain barrier dysfunction
cerebral ischemia reperfusion
MMP-9
Wnt/beta-catenin signaling pathway
Isoflurane-Induced Postoperative Neurovascular and Cognitive Dysfunction Is Associated with VEGF Overexpression in Aged Rats
期刊论文
JOURNAL OF MOLECULAR NEUROSCIENCE, 2019, 卷号: 69, 期号: 2
作者:
Cao, Yiyun
;
Li, Zhengqian
;
Ma, Lijun
;
Yang, Ning
;
Guo, Xiangyang
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/06
Isoflurane
Postoperative cognitive dysfunction
Vascular endothelial growth factor
Blood-brain barrier
Kaempferol attenuates neuroinflammation and blood brain barrier dysfunction to improve neurological deficits in cerebral ischemia/reperfusion rats
期刊论文
2019, 卷号: 1722, 页码: 146361
作者:
Li Wei-Han
;
Cheng Xiao
;
Yang Ying-Lin
;
Liu Man
;
Zhang Shan-Shan
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/01/03
Cerebral ischemia/reperfusion (I/R)
Cytokines
Inflammation
Microglial activation
NF-κB pathway
Delivery systems for theranostics in neurodegenerative diseases
期刊论文
NANO RESEARCH, 2018, 卷号: 11, 期号: 10, 页码: 5535-5555
作者:
Li, Yan
;
Liu, Ruiyuan
;
Ji, Weihong
;
Li, Yanhui
;
Liu, Linying
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2018/12/04
Neurodegenerative Diseases
Theranostics
Blood-brain Barrier
Delivery Systems
Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 12, 页码: 3117-3125
作者:
Liu, Wenwen
;
Wang, Huan
;
Li, Xiaokang
;
Xu, Yixiang
;
Zhang, Jian
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Depression
Cognitive impairment
Multitarget-directed ligand
5-HT1A agonist
5-HT reuptake inhibition
ChE inhibition
Design, Synthesis, and Biological Evaluation of Orally Available First-Generation Dual-Target Selective Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) for the Treatment of Alzheimer's Disease
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2018, 卷号: 9, 期号: 2, 页码: 328-345
作者:
Mao, Fei
;
Wang, Huan
;
Ni, Wei
;
Zheng, Xinyu
;
Wang, Manjiong
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2019/01/08
Alzheimer's disease
drug repositioning
dual-target inhibitor
AChE inhibition
PDE5 inhibition
Blood-brain barrier dysfunction and recovery after ischemic stroke
期刊论文
PROGRESS IN NEUROBIOLOGY, 2018, 卷号: 163
作者:
Jiang, Xiaoyan
;
Andjelkovic, Anuska V.
;
Zhu, Ling
;
Yang, Tuo
;
Bennett, Michael V. L.
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Inflammation
Neurovascular unit
Repair
Stroke comorbidities
Tight junction
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