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Real-time structural signatures of protein allostery by electrically- and mechanically-coupled sensing 期刊论文
NANO TODAY, 2024, 卷号: 55, 页码: 10
作者:  Zhang, Mingkun;  Zheng, Zhi;  Zhou, Jin;  Ding, Qihan;  Long, Mian
收藏  |  浏览/下载:1/0  |  提交时间:2024/03/25
Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15111-15125
作者:  Zhang, Huimin;  He, Jixiao;  Hu, Guang;  Zhu, Fei;  Jiang, Hao
收藏  |  浏览/下载:35/0  |  提交时间:2022/01/04
Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel alpha-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 17
作者:  Xie, Hong-Xu;  Zhang, Juan;  Li, Yue;  Zhang, Jin-He;  Liu, Shan-Kui
收藏  |  浏览/下载:68/0  |  提交时间:2021/11/04
Structures of full-length glycoprotein hormone receptor signalling complexes 期刊论文
NATURE, 2021, 页码: 24
作者:  Duan, Jia;  Xu, Peiyu;  Cheng, Xi;  Mao, Chunyou;  Croll, Tristan
收藏  |  浏览/下载:52/0  |  提交时间:2021/11/04
Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 15
作者:  Lu, Shaoyong;  He, Xinheng;  Yang, Zhao;  Chai, Zongtao;  Zhou, Shuhua
收藏  |  浏览/下载:34/0  |  提交时间:2021/11/04
Affinity Mass Spectrometry-Based Fragment Screening Identified a New Negative Allosteric Modulator of the Adenosine A(2A) Receptor Targeting the Sodium Ion Pocket 期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 6, 页码: 991-1002
作者:  Lu, Yan;  Liu, Hongyue;  Yang, Dehua;  Zhong, Li;  Xin, Ye
收藏  |  浏览/下载:25/0  |  提交时间:2021/08/17
Allosteric Modulation: Dynamics is Double-"E"dged 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 7, 页码: 3694-3696
作者:  Xiong, Bing
收藏  |  浏览/下载:14/0  |  提交时间:2021/06/11
Multi-scale molecular dynamics simulations and applications on mechanosensitive proteins of integrins* 期刊论文
CHINESE PHYSICS B, 2021, 卷号: 30, 期号: 3, 页码: 8
作者:  Lu, Shouqin;  Ding, Qihan;  Zhang, Mingkun;  Long, Mian
收藏  |  浏览/下载:13/0  |  提交时间:2021/04/20
Multi-scale molecular dynamics simulations and applications on mechanosensitive proteins of integrins* 期刊论文
CHINESE PHYSICS B, 2021, 卷号: 30, 期号: 3, 页码: 8
作者:  Lv SQ(吕守芹);  Ding QH(丁奇寒);  Zhang MK(张明坤);  Long M(龙勉)
收藏  |  浏览/下载:16/0  |  提交时间:2021/04/19
Insights into the molecular mechanism of positive cooperativity between partial agonist MK-8666 and full allosteric agonist AP8 of hGPR40 by Gaussian accelerated molecular dynamics (GaMD) simulations 期刊论文
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2021, 卷号: 19, 页码: 3978-3989
作者:  An, Xiaoli;  Bai, Qifeng;  Bing, Zhitong;  Liu, Huanxiang;  Yao, Xiaojun
收藏  |  浏览/下载:12/0  |  提交时间:2021/12/08


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