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浏览/检索结果: 共9条，第1-9条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 Structural studies and drug discovery of G protein-coupled receptors 期刊论文 Kexue Tongbao/Chinese Science Bulletin, 2018, 卷号: 63, 期号: 14, 页码: 1361-1373 作者:  Yang, Zhenlin;  Wu, Beili 收藏  |  浏览/下载：54/0  |  提交时间：2019/01/08 Structural studies and drug discovery of G protein-coupled receptors 期刊论文 Chinese Science Bulletin, 2018, 卷号: 63, 期号: 14, 页码: 1362-1373 作者:  Yang Zhenlin;  Wu Beili 收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08 G protein-coupled receptor  drug target  3D structure  ligand  structure-based drug discovery   Structural Determinants of Binding the Seven-transmembrane Domain of the Glucagon-like Peptide-1 Receptor (GLP-1R) 期刊论文 JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 291, 期号: 25, 页码: 12991-13004 作者:  Yang, Dehua;  de Graaf, Chris;  Yang, Linlin;  Song, Gaojie;  Dai, Antao 收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice 期刊论文 DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286 作者:  Feng, Li;  Luo, Huan;  Xu, Zhijian;  Yang, Zhuo;  Du, Guoxin 收藏  |  浏览/下载：26/0  |  提交时间：2016/08/22 Alternative binding site  Bavachinin  Canonical ligand-binding pocket  Carbohydrate metabolism  Lipid metabolism  Pan-PPAR agonist  Synergistic effects   Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice 期刊论文 DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286 作者:  Feng, Li;  Luo, Huan;  Xu, Zhijian;  Yang, Zhuo;  Du, Guoxin 收藏  |  浏览/下载：47/0  |  提交时间：2019/01/08 Alternative binding site  Bavachinin  Canonical ligand-binding pocket  Carbohydrate metabolism  Lipid metabolism  Pan-PPAR agonist  Synergistic effects   Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice 期刊论文 DIABETOLOGIA, 2016, 卷号: 59, 期号: 6 作者:  Feng, Li;  Luo, Huan;  Xu, Zhijian;  Yang, Zhuo;  Du, Guoxin 收藏  |  浏览/下载：12/0  |  提交时间：2019/12/05 Alternative binding site  Bavachinin  Canonical ligand-binding pocket  Carbohydrate metabolism  Lipid metabolism  Pan-PPAR agonist  Synergistic effects   Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-γ and PPAR-α agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice 期刊论文 Diabetologia, 2016, 卷号: 59, 页码: 1276-86 作者:  Feng Li[1];  Luo Huan[2];  Xu Zhijian[3];  Yang Zhuo[4];  Du Guoxin[5] 收藏  |  浏览/下载：9/0  |  提交时间：2019/04/26 Alternative binding site  Bavachinin  Canonical ligand-binding pocket  Carbohydrate metabolism  Lipid metabolism  Pan-PPAR agonist  Synergistic effects   The Crystal Structure of the Orphan Nuclear Receptor NR2E3/PNR Ligand Binding Domain Reveals a Dimeric Auto-Repressed Conformation 期刊论文 PLOS ONE, 2013, 卷号: 8, 期号: 9 作者:  Tan, M. H. Eileen;  Zhou, X. Edward;  Soon, Fen-Fen;  Li, Xiaodan;  Li, Jun 收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 Structural Basis for Hydroxycholesterols as Natural Ligands of Orphan Nuclear Receptor ROR gamma 期刊论文 http://dx.doi.org/10.1210/me.2009-0507, 2010 Jin, Lihua; Martynowski, Dariusz; Zheng, Songyang; Wada, Taira; Xie, Wen; Li, Yong; 金利华; 李勇 收藏  |  浏览/下载：4/0  |  提交时间：2015/07/22 ALPHA  LXR  OXYSTEROLS  IDENTIFICATION  CHOLESTEROL  RECRUITMENT  METABOLISM  ACTIVATION  PATHWAY