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Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-γ and PPAR-α agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice
Feng Li[1]; Luo Huan[2]; Xu Zhijian[3]; Yang Zhuo[4]; Du Guoxin[5]; Zhang Yu[6]; Yu Lijing[7]; Hu Kaifeng[8]; Zhu Weiliang[9]; Tong Qingchun[10]
刊名Diabetologia
2016
卷号59页码:1276-86
关键词Alternative binding site Bavachinin Canonical ligand-binding pocket Carbohydrate metabolism Lipid metabolism Pan-PPAR agonist Synergistic effects
ISSN号1432-0428
URL标识查看原文
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/2236535
专题上海大学
作者单位1.[1]Department of TCM Chemistry, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai, 201203, People's Republic of China.
2.[2]State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People's Republic of China.
3.[3]CAS Key Laboratory for Membrane Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, People's Republic of China.
4.[4]CAS Key Laboratory for Membrane Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, People's Republic of China.
5.[5]Department of TCM Chemistry, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai, 201203, People's Republic of China.
6.[6]Laboratory of Drug Discovery, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai, 201203, People's Republic of China.
7.[7]Laboratory of Drug Discovery, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai, 201203, People's Republic of China.
8.[8]State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People's Republic of China.
9.[9]CAS Key Laboratory for Membrane Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, People's Republic of China.
10.[10]The Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.
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GB/T 7714
Feng Li[1],Luo Huan[2],Xu Zhijian[3],et al. Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-γ and PPAR-α agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice[J]. Diabetologia,2016,59:1276-86.
APA Feng Li[1].,Luo Huan[2].,Xu Zhijian[3].,Yang Zhuo[4].,Du Guoxin[5].,...&Li Yiming[14].(2016).Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-γ and PPAR-α agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice.Diabetologia,59,1276-86.
MLA Feng Li[1],et al."Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-γ and PPAR-α agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice".Diabetologia 59(2016):1276-86.
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