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Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens
收藏  |  浏览/下载:74/0  |  提交时间:2021/08/17
Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:  Yu, Ming-cheng;  Yang, Feng;  Ding, Xiao-yu;  Sun, Nan-nan;  Jiang, Zheng-yuan
收藏  |  浏览/下载:85/0  |  提交时间:2020/12/24
Erectsterates A and B, a pair of novel highly degraded steroid derivatives from the South China Sea soft coral Sinularia erecta 期刊论文
STEROIDS, 2020, 卷号: 161, 页码: 5
作者:  Liu, Jiao;  Wu, Xin;  Yang, Min;  Gu, Yu-Cheng;  Yao, Li-Gong
收藏  |  浏览/下载:18/0  |  提交时间:2020/12/24
Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 9, 页码: 10
作者:  Hou, Zeng;  Min, Wenjian;  Zhang, Rukang;  Niu, Ao;  Li, Yuanqing
收藏  |  浏览/下载:44/0  |  提交时间:2020/07/01
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma 期刊论文
JOURNAL OF HEPATOLOGY, 2020, 卷号: 72, 期号: 5, 页码: 896-908
作者:  Dong, Liang-qing;  Peng, Li-hua;  Ma, Li-jie;  Liu, Dong-bing;  Zhang, Shu
收藏  |  浏览/下载:64/0  |  提交时间:2020/07/01
Computational discovery and biological evaluation of novel inhibitors targeting histone-lysine N-methyltransferase SET7 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 7, 页码: 10
作者:  Min, Wenjian;  Hou, Zeng;  Zhang, Fang;  Xie, Shengnan;  Yuan, Kai
收藏  |  浏览/下载:50/0  |  提交时间:2020/07/01
A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer 期刊论文
CELL METABOLISM, 2019, 卷号: 30, 期号: 6, 页码: 1107-+
作者:  Huang, Ke;  Liang, Qian;  Zhou, Ye;  Jiang, Lu-lu;  Gu, Wei-ming
收藏  |  浏览/下载:77/0  |  提交时间:2020/07/01
Identification of a new inhibitor of KRAS-PDE delta interaction targeting KRAS mutant nonsmall cell lung cancer 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2019, 卷号: 145, 期号: 5, 页码: 1334-1345
作者:  Leung, Elaine Lai-Han;  Luo, Lian Xiang;  Li, Ying;  Liu, Zhong-Qiu;  Li, Lan Lan
收藏  |  浏览/下载:14/0  |  提交时间:2020/07/01
Engineering nanoparticles to locally activate T cells in the tumor microenvironment 期刊论文
SCIENCE IMMUNOLOGY, 2019, 卷号: 4, 期号: 37, 页码: 13
作者:  Wang, Dangge;  Wang, Tingting;  Yu, Haijun;  Feng, Bing;  Zhou, Lei
收藏  |  浏览/下载:22/0  |  提交时间:2020/07/01
Identification of recurrent USP48 and BRAF mutations in Cushing's disease 期刊论文
NATURE COMMUNICATIONS, 2018, 卷号: 9
作者:  Chen, Jianhua;  Jian, Xuemin;  Deng, Siyu;  Ma, Zengyi;  Shou, Xuefei
收藏  |  浏览/下载:117/0  |  提交时间:2019/01/08


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