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浏览/检索结果: 共22条，第1-10条 帮助 限定条件 发表日期：2019    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070 作者:  Xiao, Li;  Wang, Yujun;  Zhang, Mumei;  Wu, Weiwei;  Kong, Linghui 收藏  |  浏览/下载：92/0  |  提交时间：2020/07/01 AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition 期刊论文 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1587-1595 作者:  Zhang, Kai-li;  Shen, Qian-qian;  Fang, Yan-fen;  Sun, Yi-ming;  Ding, Jian 收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01 PRC2  EZH2-EED  AZD9291  miR-34a  non-canonical base pairing   Fluorescence imaging of a potential diagnostic biomarker for breast cancer cells using a peptide-functionalized fluorogenic 2D material 期刊论文 CHEMICAL COMMUNICATIONS, 2019, 卷号: 55, 期号: 88, 页码: 13235-13238 作者:  Dou, Wei-Tao;  Liu, Li-Fang;  Gao, Jie;  Zang, Yi;  Chen, Guo-Rong 收藏  |  浏览/下载：13/0  |  提交时间：2020/07/01 PD-L1 expression levels on tumor cells affect their immunosuppressive activity 期刊论文 ONCOLOGY LETTERS, 2019, 卷号: 18, 期号: 5, 页码: 5399-5407 作者:  Zheng, Yang;  Fang, You-Chen;  Li, Jing 收藏  |  浏览/下载：53/0  |  提交时间：2020/07/01 programmed cell death 1  programmed death-ligand 1  co-culture  immunosuppression  signaling pathway   A comprehensive study of pomegranate flowers polyphenols and metabolites in rat biological samples by high-performance liquid chromatography quadrupole time-of-flight mass spectrometry 期刊论文 JOURNAL OF CHROMATOGRAPHY A, 2019, 卷号: 1604, 页码: 13 作者:  Yisimayili, Zainaipuguli;  Abdulla, Rahima;  Tian, Qiang;  Wang, Yangyang;  Chen, Mingcang 收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01 Punica granatum L. flowers  Polyphenols  Ellagitannin  Metabolism  HPLC-Q-TOF-MS2   Identifying the active components of Baihe-Zhimu decoction that ameliorate depressive disease by an effective integrated strategy: a systemic pharmacokinetics study combined with classical depression model tests 期刊论文 CHINESE MEDICINE, 2019, 卷号: 14, 期号: 1, 页码: 11 作者:  Zhong, Ming;  Tian, Xiaoting;  Chen, Shuoji;  Chen, Mingcang;  Guo, Ziqiong 收藏  |  浏览/下载：28/0  |  提交时间：2020/07/01 Baihe-Zhimu decoction  Antidepressant  Timosaponin BII  Timosaponin BIII  Drug discovery   The Study of Release Mechanisms for Drug in Cyclodextrin Metal-Organic Frameworks 期刊论文 ACS OMEGA, 2019, 卷号: 4, 期号: 11, 页码: 14490-14496 作者:  Liu, Congbiao;  Guo, Tao;  Li, Weimin;  Jiang, Zhiteng;  Chen, Min 收藏  |  浏览/下载：13/0  |  提交时间：2020/07/01 Determining the protective effects of Yin-Chen-Hao Tang against acute liver injury induced by carbon tetrachloride using 16S rRNA gene sequencing and LC/MS-based metabolomics 期刊论文 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 174, 页码: 567-577 作者:  Liu, Fang;  Sun, Zhaolin;  Hu, Pei;  Tian, Qiang;  Xu, Zhou 收藏  |  浏览/下载：23/0  |  提交时间：2020/07/01 Yin-Chen-Hao Tang  Liver injury  Metabolomics  Gut microbiota  LC-MS  Gene sequencing   Suadimins A-C, Unprecedented Dimeric Quinoline Alkaloids with Antimycobacterial Activity from Melodinus suaveolens 期刊论文 ORGANIC LETTERS, 2019, 卷号: 21, 期号: 17, 页码: 7065-7068 作者:  Gao, Xin-Hua;  Fan, Yao-Yue;  Liu, Qun-Fang;  Cho, Sang-Hyun;  Pauli, Guido F. 收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 Discovery of a novel third generation EGFR TKI and identification of its potential mechanism of resistance 期刊论文 CANCER RESEARCH, 2019, 卷号: 79, 期号: 13, 页码: 2 作者:  Zhang, Tao;  Qu, Rong;  Chen, Chengbin;  Tong, Linjiang;  Feng, Fang 收藏  |  浏览/下载：4/0  |  提交时间：2020/07/01