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浏览/检索结果: 共31条，第1-10条 帮助 限定条件 发表日期：2019    内容类型：期刊论文    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer 期刊论文 CELL METABOLISM, 2019, 卷号: 30, 期号: 6, 页码: 1107-+ 作者:  Huang, Ke;  Liang, Qian;  Zhou, Ye;  Jiang, Lu-lu;  Gu, Wei-ming 收藏  |  浏览/下载：77/0  |  提交时间：2020/07/01 AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition 期刊论文 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1587-1595 作者:  Zhang, Kai-li;  Shen, Qian-qian;  Fang, Yan-fen;  Sun, Yi-ming;  Ding, Jian 收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01 PRC2  EZH2-EED  AZD9291  miR-34a  non-canonical base pairing   Selective activation of TWIK-related acid-sensitive K+ 3 subunit-containing channels is analgesic in rodent models 期刊论文 SCIENCE TRANSLATIONAL MEDICINE, 2019, 卷号: 11, 期号: 519, 页码: 12 作者:  Liao, Ping;  Qiu, Yunguang;  Mo, Yiqing;  Fu, Jie;  Song, Zhenpeng 收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01 YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression 期刊论文 NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 14 作者:  Shi, Yulin;  Fan, Songqing;  Wu, Mengge;  Zuo, Zhixiang;  Li, Xingyang 收藏  |  浏览/下载：56/0  |  提交时间：2020/07/01 Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice 期刊论文 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1279-1291 作者:  Fan, Lei;  Qiu, Xiao-xia;  Zhu, Zhi-yuan;  Lv, Jian-lu;  Lu, Jian 收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01 Alzheimer's disease  nitazoxanide  autophagy  inflammation  APP/PS1 transgenic mice   Structure-Based Discovery and Development of a Series of Potent and Selective Bromodomain and Extra-Terminal Protein Inhibitors 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 18, 页码: 8642-8663 作者:  Hu, Jianping;  Tian, Chang-Qing;  Damaneh, Mohammadali Soleimani;  Li, Yanlian;  Cao, Danyan 收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01 Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice 期刊论文 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1193-1204 作者:  Zhou, Ting-ting;  Zhao, Tong;  Ma, Fei;  Zhang, Yi-nan;  Jiang, Jing 收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01 type 2 diabetes mellitus  hepatic gluconeogenesis  AMPK signaling pathway  (E)-3-(2-(quinoline-4-yl)vinyl)-1H-indol-6-ol (QVO)  4-[2-(1H-indol-3-yl)vinyl]quinoline (IVQ)  prodrug   Preclinical evaluation of 3D185, a novel potent inhibitor of FGFR1/2/3 and CSF-1R, in FGFR-dependent and macrophage-dominant cancer models 期刊论文 JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2019, 卷号: 38, 期号: 1, 页码: 16 作者:  Peng, Xia;  Hou, Pengcong;  Chen, Yi;  Dai, Yang;  Ji, Yinchun 收藏  |  浏览/下载：6/0  |  提交时间：2020/07/01 Kinase inhibitor  FGFR  CSF-1R  Tumor microenvironment   Metal-free quinolylation of the primary amino groups of amino acid derivatives and peptides with dihydrooxazolo[3,2-a]quinoliniums 期刊论文 GREEN CHEMISTRY, 2019, 卷号: 21, 期号: 15, 页码: 4231-4237 作者:  Liu, Peng;  Li, Bo;  Xi, Mengyu;  Chen, Zhaoqiang;  Sun, Haiguo 收藏  |  浏览/下载：9/0  |  提交时间：2020/07/01 Characterization of TPN171 metabolism in humans via ultra-performance liquid chromatography/quadrupole time-of-flight Checir for mass spectrometry 期刊论文 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 172, 页码: 302-310 作者:  Pan, Lulu;  Guo, Shuang;  Chen, Xiaoyan;  Jiang, Xiangrui;  Shen, Jingshan 收藏  |  浏览/下载：53/0  |  提交时间：2020/07/01 TPNI71  Metabolism  UPLC/Q-TOF MS  High-resolution mass spectrometry  Metabolite identification