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科研机构
上海药物研究所 [42]
内容类型
期刊论文 [34]
项目 [8]
发表日期
2022 [2]
2021 [2]
2020 [2]
2019 [4]
2018 [7]
2017 [6]
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Multi-level fingerprinting and cardiomyocyte protection evaluation for comparing polysaccharides from six Panax herbal medicines
期刊论文
CARBOHYDRATE POLYMERS, 2022, 卷号: 277, 页码: 10
作者:
Liu, Jie
;
Wang, Hong-da
;
Yang, Fei-fei
;
Chen, Bo-xue
;
Li, Xue
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2022/01/04
Panax
Polysaccharide
Oligosaccharide spectrum
Untargeted metabolomics
Cardiomyocyte protection
Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine[ZYYCXTD-D-202002]
项目
项目编号: ZYYCXTD-D-202002, 资助机构: Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine, 2022-
-
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/01/04
CsCCD2 Access Tunnel Design for a Broader Substrate Profile in Crocetin Production
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 39, 页码: 11626-11636
作者:
Liang, Nan
;
Yao, Ming-Dong
;
Wang, Ying
;
Liu, Jia
;
Feng, Lu
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/12/01
crocetin
CCD2
access tunnel engineering
Saccharomyces cerevisiae
Plant metabolomics for studying the effect of two insecticides on comprehensive constituents of Lonicerae Japonicae Flos
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2021, 卷号: 19, 期号: 1, 页码: 70-80
作者:
Pan Hui-Qin
;
Zhou Heng
;
Miao Shui
;
Guo De-An
;
Zhang Xiao-Li
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/05/24
Plant metabolomics
Insecticide
Metabolite variation
Lonicerae Japonicae Flos
Asperbutenolide A, an unusual aromatic butenolide dimer with diverse bioactivities from a marine-derived fungus Aspergillus terreus SCAU011
期刊论文
TETRAHEDRON LETTERS, 2020, 卷号: 61, 期号: 32, 页码: 6
作者:
Bao, Jie
;
Li, Xiu-Xiu
;
He, Fei
;
Zhang, Xiaoyong
;
Zhu, Kongkai
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/12/24
Aspergillus terreus
Asperbutenolide A
Butyrolactone
Butenolide
Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations
期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 1, 页码: 58-63
作者:
Zhu, Kongkai
;
Du, Daohai
;
Yang, Rui
;
Tao, Hongrui
;
Zhang, Hua
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
polycomb repressive complex 2
EZH2-EED interaction inhibitor
virtual screening
molecular dynamics simulation
Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity
期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 8, 页码: 775-785
作者:
Zhu, Kongkai
;
Shao, Jingwei
;
Tao, Hongrui
;
Yan, Xue
;
Luo, Cheng
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
PRMT5 inhibitor
Anti-proliferative
Cellular target validation
Design and synthesis
Discovery of New Selective Butyrylcholinesterase (BChE) Inhibitors with Anti-A beta Aggregation Activity: Structure-Based Virtual Screening, Hit Optimization and Biological Evaluation
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 14, 页码: 21
作者:
Jiang, Cheng-Shi
;
Ge, Yong-Xi
;
Cheng, Zhi-Qiang
;
Wang, Yin-Yin
;
Tao, Hong-Rui
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
selective BChE inhibitor
virtual screening
structural optimization
molecular dynamics
anti-A beta aggregation
Discovery of new multifunctional selective acetylcholinesterase inhibitors: structure-based virtual screening and biological evaluation
期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 5, 页码: 521-530
作者:
Jiang, Cheng-Shi
;
Ge, Yong-Xi
;
Cheng, Zhi-Qiang
;
Song, Jia-Li
;
Wang, Yin-Yin
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
AChE inhibitor
Pharmacophore model
Molecular docking
Anti-A aggregation
Neuroprotective activity
Discovery of Novel PRMT5 Inhibitors by Virtual Screening and Biological Evaluations
期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2019, 卷号: 67, 期号: 4, 页码: 382-388
作者:
Tao, Hongrui
;
Yan, Xue
;
Zhu, Kongkai
;
Zhang, Hua
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
virtual screening
epigenetic inhibitor
antiproliferation
molecular docking
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