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科研机构
上海药物研究所 [114]
内容类型
期刊论文 [110]
会议论文 [2]
学位论文 [2]
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2021 [5]
2020 [6]
2019 [5]
2018 [11]
2017 [3]
2016 [6]
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Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
A simultaneous identification and quantification strategy for determination of sulfhydryl-containing metabolites in normal- and high-fat diet hamsters using stable isotope labeling combined with LC-MS
期刊论文
ANALYTICA CHIMICA ACTA, 2021, 卷号: 1184, 页码: 13
作者:
Chang, Lu
;
Lin, Feifei
;
Cheng, Kai
;
Li, Jiaomeng
;
Sun, Xiaochu
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2022/01/18
Sulfhydryl-containing metabolites
Stable isotope labeling
Identification
Quantification
Hyperlipidemia
Oxidative stress
Endogenous Stimuli-Activatable Nanomedicine for Immune Theranostics for Cancer
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2021, 卷号: 31, 期号: 26, 页码: 30
作者:
Wang, Weiqi
;
Jin, Yilan
;
Liu, Xiao
;
Chen, Fangmin
;
Zheng, Xiaohua
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2021/08/17
cancer immunotherapy
immune diagnosis
nanomedicine
stimuli-responsive
tumor microenvironment
Aristolochic acid I promoted clonal expansion but did not induce hepatocellular carcinoma in adult rats
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Liu, Yong-zhen
;
Lu, Heng-lei
;
Qi, Xin-ming
;
Xing, Guo-zhen
;
Wang, Xin
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2021/05/24
aristolochic acid I
glutathione S-transferase placental form-positive foci
clonal expansion
hepatocellular carcinoma
medium-term rat liver bioassay
DNA adducts
Protective Effects of 28-O-Caffeoyl Betulin (B-CA) on the Cerebral Cortex of Ischemic Rats Revealed by a NMR-Based Metabolomics Analysis
期刊论文
NEUROCHEMICAL RESEARCH, 2021, 页码: 13
作者:
Liu, Xia
;
Ruan, Zhi
;
Shao, Xing-cheng
;
Feng, Hong-xuan
;
Wu, Lei
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
Cerebral ischemia–
reperfusion
28-O-caffeoyl betulin
Neuroprotection
Metabolomics
NMR
Selective and sensitive fluorescence imaging reveals microenvironment-dependent behavior of NO modulators in the endothelial system
期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2020, 卷号: 10, 期号: 5, 页码: 466-472
作者:
Dong, Ying
;
Li, Xiao-Rong
;
Li, Jia
;
Zang, Yi
;
Li, Xin
收藏
  |  
浏览/下载:107/0
  |  
提交时间:2020/12/21
Nitric oxide modulator
Drug screen
Fluorescence imaging
Microenvironment
Endothelial cell
An Integrated LC-MS/MS Strategy for Quantifying the Oxidative-Redox Metabolome in Multiple Biological Samples
期刊论文
ANALYTICAL CHEMISTRY, 2020, 卷号: 92, 期号: 13, 页码: 8810-8818
作者:
Liu, Huiying
;
Xu, Feng
;
Gao, Yuqing
;
Pang, Yuanyuan
;
Xie, Cen
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2020/12/24
Photothermal-reinforced and glutathione-triggered in Situ cascaded nanocatalytic therapy
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2020, 卷号: 321, 页码: 734-743
作者:
An, Peijing
;
Fan, Fengying
;
Gu, Dihai
;
Gao, Zhiguo
;
Hossain, Abul Monsur Showkot
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/07/01
Nanocatalytic medicine
Synergistic therapy
Chemodynamic therapy
Photothermal-enhanced GSH depletion
GSH-triggered ROS generation
Engineering Stimuli-Activatable Boolean Logic Prodrug Nanoparticles for Combination Cancer Immunotherapy
期刊论文
ADVANCED MATERIALS, 2020, 页码: 11
作者:
Hou, Bo
;
Zhou, Lei
;
Wang, Hui
;
Saeed, Madiha
;
Wang, Dangge
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/07/01
Boolean logic gates
cancer immunotherapy
prodrug nanoparticles
stimuli activation
tumor microenvironment
Self-assembling mertansine prodrug improves tolerability and efficacy of chemotherapy against metastatic triple-negative breast cancer
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2020, 卷号: 318, 页码: 234-245
作者:
Ran, Wei
;
Liu, Xiaoyu
;
Chang, Lu
;
Cai, Ying
;
Zheng, Chao
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
Supramolecular
Self-assembly
Prodrug
Chemotherapy
Triple-negative breast cancer
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