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山东大学 [41]
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期刊论文 [193]
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fDiscovery of pyrazole-thiophene derivatives as highly Potent, orally active Akt inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 72-85
作者:
Zhan, Wenhu
;
Che, Jinxin
;
Xu, Lei
;
Wu, Yizhe
;
Hu, Xiaobei
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
Pyrazole-thiophene derivatives
Akt inhibitor
Antitumor
Discovery of 1,3-diphenyl-1H-pyrazole derivatives containing rhodanine-3-alkanoic acid groups as potential PTP1B inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 10, 页码: 1187-1193
作者:
Sun, Liangpeng
;
Wang, Peipei
;
Xu, Lili
;
Gao, Lixin
;
Li, Jia
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  |  
浏览/下载:4/0
  |  
提交时间:2020/07/01
PTP1B inhibitor
1,3-Diphenyl-1H-pyrazole
Rhodanine-3-alkanoic acid
Synthesis, biological evaluation and molecular docking of benzimidazole grafted benzsulfamide-containing pyrazole ring derivatives as novel tubulin polymerization inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 3
作者:
Shi, Tian-Qi
;
Wang, Yan-Ting
;
Liu, Chang-Hong
;
Zhu, Hai-Liang
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Benzimidazole
Benzsulfamide
Pyrazole
Tubulin
Inhibition
Apoptosis
Molecular docking
Discovery of novel bacterial FabH inhibitors (Pyrazol-Benzimidazole amide derivatives): Design, synthesis, bioassay, molecular docking and crystal structure determination
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 171
作者:
Wang, Yan-Ting
;
Shi, Tian-Qi
;
Fu, Jie
;
Zhu, Hai-Liang
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  |  
浏览/下载:14/0
  |  
提交时间:2019/12/05
FabH
Inhibitor
Pyrazole
Antibacterial
Molecule docking
Synthesis and bioevaluation of diarylpyrazoles as antiproliferative agents
期刊论文
European Journal of Medicinal Chemistry, 2019
作者:
Chao Wang
;
Shuang Yang
;
Jianan Du
;
Jia Ni
;
Yue Wu
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  |  
浏览/下载:7/0
  |  
提交时间:2019/12/13
CA-4
Tubulin
Pyrazole
Colchicine
binding
site
Design, synthesis, and biological evaluation of 2-(5-methyl-1H-pyrazol-1-yl) acetamide derivatives as androgen receptor antagonists
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2019, 卷号: 28, 期号: 3, 页码: 380-386
作者:
Dong, Junze
;
Zhang, Jingya
;
Li, Zilu
;
Asnake, Solomon
;
Zhang, Daoguang
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  |  
浏览/下载:15/0
  |  
提交时间:2019/12/11
Androgen receptor
Prostate cancer
Antagonists
Pyrazole derivatives
Discovery of novel pyrazole derivatives as potential anticancer agents in MCL
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 9, 页码: 1060-1064
作者:
Ran, Fansheng
;
Liu, Yang
;
Zhang, Daoguang
;
Liu, Meixia
;
Zhao, Guisen
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  |  
浏览/下载:28/0
  |  
提交时间:2019/12/11
Mantle cell lymphoma
BTK
Irreversible inhibitors
Anticancer
Pyrazole
derivatives
Excellent antitumor and antimetastatic activities based on novel coumarin/pyrazole oxime hybrids.
期刊论文
European journal of medicinal chemistry, 2019, 卷号: Vol.166, 页码: 470-479
作者:
Hong Dai
;
Meiling Huang
;
Jianqiang Qian
;
Ji Liu
;
Chi Meng
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  |  
浏览/下载:22/0
  |  
提交时间:2019/12/17
Antimetastasis
Antitumor
activity
Coumarin
Hybrids
Pyrazole
oxime
Pyrazole-Isoindoline-1,3-dione Hybrid: A Promising Scaffold for 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors.
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 39, 页码: 10844-10852
作者:
He, Bo
;
Dong, Jin
;
Lin, Hong-Yan
;
Wang, Meng-Yao
;
Li, Xian-Kai
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/23
4-hydroxyphenylpyruvate dioxygenase
X-ray crystallography
inhibition kinetics
isoindoline-1,3-dione
pyrazole
Visible-light promoted one-pot synthesis of pyrazoles from alkynes and hydrazines
期刊论文
TETRAHEDRON LETTERS, 2019, 卷号: 60, 期号: 2, 页码: 171-174
作者:
Meng, Yunge[1]
;
Zhang, Te[2]
;
Gong, Xinchi[3]
;
Zhang, Min[4]
;
Zhu, Chunyin[5]
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  |  
浏览/下载:9/0
  |  
提交时间:2019/12/24
Alkyne
Pyrazole
Visible-light
Cascade
Synthesis
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