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CORC

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Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090
作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan
收藏  |  浏览/下载：23/0  |  提交时间：2022/01/04
Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong
收藏  |  浏览/下载：17/0  |  提交时间：2021/12/16
Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors 期刊论文
PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664
作者:  Xu, Jianghong;  Hu, Yuanyuan;  Liu, Xiaoqi;  Gao, Anhui;  Gao, Lixin
收藏  |  浏览/下载：37/0  |  提交时间：2021/12/01
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target 期刊论文
CELL RESEARCH, 2021, 页码: 14
作者:  Xia, Bingqing;  Shen, Xurui;  He, Yang;  Pan, Xiaoyan;  Liu, Feng-Liang
收藏  |  浏览/下载：78/0  |  提交时间：2021/08/17
Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14
作者:  Yang, Xiangbo;  Wang, Zhijia;  Pei, Yuan;  Song, Ning;  Xu, Lei
收藏  |  浏览/下载：40/0  |  提交时间：2021/08/17
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue
收藏  |  浏览/下载：22/0  |  提交时间：2020/12/21
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue
收藏  |  浏览/下载：23/0  |  提交时间：2020/12/21
Human Motion Driven Self-Powered Photodynamic System for Long-Term Autonomous Cancer Therapy 期刊论文
ACS NANO, 2020, 卷号: 14, 期号: 7, 页码: 8074-8083
作者:  Liu, Zhuo;  Xu, Lingling;  Zheng, Qiang;  Kang, Yong;  Shi, Bojing
收藏  |  浏览/下载：35/0  |  提交时间：2020/10/30
Selective N-glycan editing on living cell surfaces to probe glycoconjugate function 期刊论文
NATURE CHEMICAL BIOLOGY, 2020, 页码: 15
作者:  Tang, Feng;  Zhou, Mang;  Qin, Ken;  Shi, Wei;  Yashinov, Ansor
收藏  |  浏览/下载：72/0  |  提交时间：2020/07/01
Performance of a novel multiple draft tubes airlift loop membrane bioreactor to treat ampicillin pharmaceutical wastewater under different temperatures 期刊论文
CHEMICAL ENGINEERING JOURNAL, 2020, 卷号: 380, 页码: 1-14
作者:  Chen, Zhaobo;  Min, Hongchao;  Hu, Dongxue;  Wang, Hongcheng;  Zhao, Yuanyi
收藏  |  浏览/下载：25/0  |  提交时间：2021/09/15

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