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Repressing MYC by targeting BET synergizes with selective inhibition of PI3K alpha against B cell lymphoma
期刊论文
CANCER LETTERS, 2022, 卷号: 524, 页码: 206-218
作者:
Chen, Zi-qi
;
Cao, Zhe-rui
;
Wang, Yi
;
Zhang, Xi
;
Xu, Lan
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/12/16
CYH33
MYC
P300
BET
B cell lymphoma
PI3K
Molecular dynamics simulation revealed the intrinsic conformational change of cellular inhibitor of apoptosis protein-1
期刊论文
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2020, 卷号: 38, 期号: 4, 页码: 975-984
作者:
Xu, Heng
;
Tang, Zhengkuan
;
Zuo, Yu
;
Xiong, Fengmin
;
Chen, Kaixian
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  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
cIAP1
dimerization
conformational change
MD simulation
Arabidopsis COPPER TRANSPORTER 1 undergoes degradation in a proteasome-dependent manner
期刊论文
JOURNAL OF EXPERIMENTAL BOTANY, 2020, 卷号: 71, 期号: 19, 页码: 6174-6186
作者:
Li, Jinjin
;
Yuan, Jinhong
;
Wang, Hui
;
Zhang, Hui
;
Zhang, Haiyan
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  |  
浏览/下载:36/0
  |  
提交时间:2022/03/01
Arabidopsis
copper transporter
degradation
proteasome
ubiquitination
vesicle trafficking
Inhibition of HSP90 beta Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System
期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 20, 页码: 5769-5783
作者:
Zheng, Zu-Guo
;
Zhang, Xin
;
Liu, Xiao-Xiao
;
Jin, Xiu-Xiu
;
Dai, Lunzhi
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  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
HSP90 beta
lipid metabolism
corylin
SREBPs
proteasomal degradation
Identification of serine 119 as an effective inhibitor binding site of m. tuberculosis ubiquitin-like protein ligase pafa using purified proteins and m. smegmatis
期刊论文
Ebiomedicine, 2018, 卷号: 30, 页码: 225-236
作者:
Jiang, He-Wei
;
Czajkowsky, Daniel M.
;
Wang, Tao
;
Wang, Xu-De
;
Wang, Jia-bin
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  |  
浏览/下载:64/0
  |  
提交时间:2019/05/08
M. tuberculosis
Pupylation
Pafa
4-(2-aminoethyl) benzenesulfonyl fluoride
SYVN1, an ERAD E3 Ubiquitin Ligase, Is Involved in GABA(A)alpha 1 Degradation Associated with Methamphetamine-Induced Conditioned Place Preference
期刊论文
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2017, 卷号: 10
作者:
Jiao, Dong-Liang
;
Chen, Yan
;
Liu, Yao
;
Ju, Yun-Yue
;
Long, Jian-Dong
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  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
methamphetamine
GABA(A)alpha 1
dorsal striatum
ERAD
SYVN1
RBR-type E3 ubiquitin ligase RNF144A targets PARP1 for ubiquitin-dependent degradation and regulates PARP inhibitor sensitivity in breast cancer cells
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 55
作者:
Zhang, Ye
;
Liao, Xiao-Hong
;
Xie, Hong-Yan
;
Shao, Zhi-Min
;
Li, Da-Qiang
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  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
breast cancer
PARP1
E3 ubiquitin-protein ligase
ubiquitination
proteasomal degradation
How does conserved dopamine neurotrophic factor protect against and rescue neurodegeneration of PC12 cells?
期刊论文
Neural Regeneration Research, 2017, 期号: 07, 页码: 1145-1151
作者:
Jia-ming Mei
;
Chao-shi Niu
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/16
nerve regeneration
conserved dopamine neurotrophic factor
Parkinson\'s disease
proteasomal inhibitor
26S proteasome
alphasynuclein
lactacystin
MG-132
glutamyl peptide hydrolase
chymotrypsin
trypsin
neural regeneration
How does conserved dopamine neurotrophic factor protect against and rescue neurodegeneration of PC12 cells?
期刊论文
中国神经再生研究(英文版), 2017, 卷号: 12, 期号: 7, 页码: 1145-1151
作者:
Mei, Jia-ming
;
Niu, Chao-shi
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/12
nerve regeneration
conserved dopamine neurotrophic factor
Parkinson\'s disease
proteasomal inhibitor
26S proteasome
alpha-synuclein
lactacystin
MG-132
glutamyl peptide hydrolase
chymotrypsin
trypsin
neural regeneration
Y-632 inhibits heat shock protein 90 (Hsp90) function by disrupting the interaction between Hsp90 and Hsp70/Hsp90 organizing protein, and exerts antitumor activity in vitro and in vivo
期刊论文
CANCER SCIENCE, 2016, 卷号: 107, 期号: 6, 页码: 782-790
作者:
Wang, Wenqian
;
Liu, Yang
;
Zhao, Zhixin
;
Xie, Chengying
;
Xu, Yongping
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Hop
Hsp90
imatinib resistance
thiol oxidation
Y-632
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