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DNA methyltransferase 1 deficiency improves macrophage motility and wound healing by ameliorating cholesterol accumulation
期刊论文
NPJ REGENERATIVE MEDICINE, 1, 2023, 卷号: 8, 页码: 29
作者:
Zhao, Chuanrong
;
Yang, Qianru
;
Tang, Runze
;
Li, Wang
;
Wang, Jin
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/07/17
HMGB1 augments cognitive impairment in sepsis-associated encephalopathy by binding to MD-2 and promoting NLRP3-induced neuroinflammation
期刊论文
PSYCHOGERIATRICS, 2021
作者:
Xiong, Yanan
;
Yang, Jilin
;
Tong, Haiyang
;
Zhu, Chenting
;
Pang, Yinhu
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/01/25
cognitive impairment
HMGB1
MD-2
neuroinflammation
NLRP3
sepsis-associated encephalopathy
MD2 blockage prevents the migration and invasion of hepatocellular carcinoma cells via inhibition of the EGFR signaling pathway
期刊论文
JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2021
作者:
Qi, Yajun
;
Fang, Qilu
;
Li, Qinglin
;
Ding, Haiying
;
Shu, Qi
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/09/06
Hepatocellular carcinoma (HCC)
myeloid differentiation protein 2 (MD2)
epidermal growth factor receptor (EGFR)
migration
invasion
Isocitrate Dehydrogenase 2 Inhibitors for the Treatment of Hematologic Malignancies: Advances and Future Opportunities
期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21
作者:
Huang, Feng
;
Tian, Tian
;
Wu, Yizhe
;
Che, Jinxin
;
Yang, Haiyan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/06/15
Isocitrate dehydrogenase 2
IDH2
mutant
inhibitors
structure-activity relationship
blood cance
The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-kappa B/NLRP3 signaling
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yang, Fang-ming
;
Fan, Di
;
Yang, Xiao-qian
;
Zhu, Feng-hua
;
Shao, Mei-juan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
dry eye disease
artemisinin derivative
beta-aminoarteether maleate
inflammation
macrophages
TLR4
inflammasome
Dracocephalum heterophyllum(DH) Exhibits Potent Anti-Proliferative Effects on Autoreactive CD4(+)T Cells and Ameliorates the Development of Experimental Autoimmune Uveitis
期刊论文
FRONTIERS IN IMMUNOLOGY, 2020, 卷号: 11
作者:
Bian, Jiang
;
Wang, Ke
;
Wang, Qilan
;
Wang, Pu
;
Wang, Ting
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/11/25
autoimmunity
proliferation
herbal medicine
T cell
experimental autoimmune uveitis
Phycocyanin Ameliorates Radiation-Induced Acute Intestinal Toxicity by Regulating the Effect of the Gut Microbiota on the TLR4/Myd88/NF-kappa B Pathway
期刊论文
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION, 2019, 页码: 10
作者:
Lu, Lina
;
Li, Wenjun
;
Sun, Chao
;
Kang, Shuhe
;
Li, Jia
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/01/19
gut microbiota
intestinal injury
phycocyanin
radiation
Phycocyanin attenuates X-ray-induced pulmonary inflammation via the TLR2-MyD88-NF-kappa B signaling pathway
期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2019, 卷号: 37, 期号: 5, 页码: 1678-1685
作者:
Liu, Q
;
Li, WJ
;
Lu, LN
;
Liu, B
;
Du, ZN
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/08
phycocyanin
inflammatory
TLR2-MyD88-NF-kappa B signaling pathway
Pharmacological characterization of TQ05310, a potent inhibitor of isocitrate dehydrogenase 2 R140Q and R172K mutants
期刊论文
CANCER SCIENCE, 2019, 页码: 9
作者:
Gao, Mingzhao
;
Zhu, Hongmei
;
Fu, Li
;
Li, Yun
;
Bao, Xubin
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
AG-221
IDH2
leukemia
R140Q
R172K
Discovery of DC_H31 as potential mutant IDH1 inhibitor through NADPH-based high throughput screening
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3229-3236
作者:
Duan, Zhe
;
Liu, Jingqiu
;
Niu, Liping
;
Wang, Jun
;
Feng, Mingqian
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/07/01
IDH1 mutation
High-throughput screening
Pan-inhibitor
2-HG
Gliomas
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