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CORC

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Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors 期刊论文
PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664
作者:  Xu, Jianghong;  Hu, Yuanyuan;  Liu, Xiaoqi;  Gao, Anhui;  Gao, Lixin
收藏  |  浏览/下载：34/0  |  提交时间：2021/12/01
Isocitrate Dehydrogenase 2 Inhibitors for the Treatment of Hematologic Malignancies: Advances and Future Opportunities 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21
作者:  Huang, Feng;  Tian, Tian;  Wu, Yizhe;  Che, Jinxin;  Yang, Haiyan
收藏  |  浏览/下载：17/0  |  提交时间：2021/06/15
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue
收藏  |  浏览/下载：20/0  |  提交时间：2020/12/21
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue
收藏  |  浏览/下载：21/0  |  提交时间：2020/12/21
Metabolic profiling reveals distinct metabolic alterations in different subtypes of pituitary adenomas and confers therapeutic targets 期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2019, 卷号: 17, 期号: 1, 页码: 13
作者:  Feng, Jie;  Gao, Hua;  Zhang, Qi;  Zhou, Yang;  Li, Chuzhong
收藏  |  浏览/下载：76/0  |  提交时间：2019/12/02
Pharmacological characterization of TQ05310, a potent inhibitor of isocitrate dehydrogenase 2 R140Q and R172K mutants 期刊论文
CANCER SCIENCE, 2019, 页码: 9
作者:  Gao, Mingzhao;  Zhu, Hongmei;  Fu, Li;  Li, Yun;  Bao, Xubin
收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01
AG-221  IDH2  leukemia  R140Q  R172K  
Synthesis and biological evaluation of 3-aryl-4-indolyl-maleimides as potent mutant isocitrate dehydrogenase-1 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 4, 页码: 589-603
作者:  Liu, Xiaoqi;  Hu, Yuanyuan;  Gao, Anhui;  Xu, Meng;  Gao, Lixin
收藏  |  浏览/下载：28/0  |  提交时间：2020/07/01
3-(7-Azaindolyl)-4-indolylmaleimides as a novel class of mutant isocitrate dehydrogenase-1 inhibitors: Design, synthesis, and biological evaluation 期刊论文
ARCHIV DER PHARMAZIE, 2018, 卷号: 351, 期号: 10
作者:  Hu, Yuanyuan;  Gao, Anhui;  Liao, Honghui;  Zhang, Mengmeng;  Xu, Gaoya
收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08
BRAF V600E, TERT, and IDH2 Mutations in Pleomorphic Xanthoastrocytoma: Observations from a Large Case-Series Study 期刊论文
WORLD NEUROSURGERY, 2018, 卷号: 120
作者:  Ma, Chengxin;  Feng, Rui;  Chen, Hong;  Hameed, N. U. Farrukh;  Aibaidula, Abudumijit
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/05
Wild-type IDH2 promotes the Warburg effect and tumor growth through HIF1 alpha in lung cancer 期刊论文
THERANOSTICS, 2018, 卷号: 8, 期号: 15
作者:  Li, Jiangjiang;  He, Ya;  Tan, Zheqiong;  Lu, Jingchen;  Li, Liling
收藏  |  浏览/下载：24/0  |  提交时间：2019/12/05

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