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5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:  Wang, Shuni;  Yang, Hong;  Su, Mingbo
收藏  |  浏览/下载:80/0  |  提交时间:2021/11/04
Role of TET Dioxygenases and DNA Hydroxymethylation in Bisphenols-Stimulated Proliferation of Breast Cancer Cells 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2020, 卷号: 128, 期号: 2, 页码: 1-8
作者:  Li, Zhe;  Lyu, Cong;  Ren, Yun;  Wang, Hailin
收藏  |  浏览/下载:27/0  |  提交时间:2021/09/14
The Development of Inhibitors Targeting the Mixed Lineage Leukemia 1 (MLL1)-WD Repeat Domain 5 Protein (WDR5) Protein-Protein Interaction 期刊论文
CURRENT MEDICINAL CHEMISTRY, 2020, 卷号: 27, 期号: 33, 页码: 5530-5542
作者:  Ye, Xiaoqing;  Chen, Gang;  Jin, Jia;  Zhang, Binzhong;  Wang, Yinda
收藏  |  浏览/下载:14/0  |  提交时间:2020/12/24
Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 8, 页码: 775-785
作者:  Zhu, Kongkai;  Shao, Jingwei;  Tao, Hongrui;  Yan, Xue;  Luo, Cheng
收藏  |  浏览/下载:12/0  |  提交时间:2020/07/01
A patent review of arginine methyltransferase inhibitors (2010-2018) 期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2019, 卷号: 29, 期号: 2, 页码: 97-114
作者:  Li, Xiao;  Wang, Chen;  Jiang, Hao;  Luo, Cheng
收藏  |  浏览/下载:8/0  |  提交时间:2020/07/01
EZH2 cooperates with gain-of-function p53 mutants to promote cancer growth and metastasis 期刊论文
EMBO JOURNAL, 2019, 卷号: 38, 期号: 5
作者:  Zhao, Yu[1];  Ding, Liya[2];  Wane, Dejie[3];  Ye, Zhenqing[4];  He, Yundong[5]
收藏  |  浏览/下载:32/0  |  提交时间:2019/12/24
Targeting PRMT5 Activity Inhibits the Malignancy of Hepatocellular Carcinoma by Promoting the Transcription of HNF4 alpha 期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 9, 页码: 2606-2617
作者:  Zheng, Bai-Nan;  Ding, Chen-Hong;  Chen, Shi-Jie;  Zhu, Kongkai;  Shao, Jingwei
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/01
Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:  Zhu, Kongkai;  Song, Jia-Li;  Tao, Hong-Rui;  Cheng, Zhi-Qiang;  Jiang, Cheng-Shi
收藏  |  浏览/下载:100/0  |  提交时间:2019/01/08
Tick-borne encephalitis virus nonstructural protein ns5 induces rantes expression dependent on the rna-dependent rna polymerase activity 期刊论文
Journal of immunology, 2018, 卷号: 201, 期号: 1, 页码: 53-68
作者:  Zheng, Zifeng;  Yang, Jieyu;  Jiang, Xuan;  Liu, Yalan;  Zhang, Xiaowei
收藏  |  浏览/下载:68/0  |  提交时间:2019/05/08
Identification and Characterizations of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Scaffold Hopping- and 2D-Molecular Fingerprint-Based Similarity Search 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 3
作者:  Ding, Hong;  Lu, Wen Chao;  Hu, Jun Chi;  Liu, Yu-Chih;  Zhang, Chen Hua
收藏  |  浏览/下载:50/0  |  提交时间:2019/01/08


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