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Complete genome analysis of pathogenic Metschnikowia bicuspidata strain MQ2101 isolated from diseased ridgetail white prawn, Exopalaemon carinicauda
期刊论文
BMC MICROBIOLOGY, 2023, 卷号: 23, 期号: 1, 页码: 17
作者:
Shi, Wen-jun
;
Zhao, Ran
;
Zhu, Jian-qiang
;
Wan, Xi-he
;
Wang, Li-bao
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/11/15
Exopalaemon carinicauda
Metschnikowia bicuspidata
Complete genome sequence
Virulence genes
Metabolic mechanism
Toxicological effects of cadmium on deep-sea mussel Gigantidas platifrons revealed by a combined proteomic and metabolomic approach
期刊论文
FRONTIERS IN MARINE SCIENCE, 2023, 卷号: 10, 页码: 18
作者:
Zhou, Li
;
Li, Mengna
;
Zhong, Zhaoshan
;
Chen, Hao
;
Wang, Minxiao
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/12/13
metal
toxicology
Mytilidae
deep-sea
omics
environment monitor
A Raman/fluorescence dual-modal imaging guided synergistic photothermal and photodynamic therapy nanoplatform for precision cancer theranostics
期刊论文
JOURNAL OF MATERIALS CHEMISTRY B, 2022, 页码: 11
作者:
Fu, Lili
;
Huang, Yan
;
Hou, Junjun
;
Sun, Mingzhao
;
Wang, Lingxiao
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  |  
浏览/下载:20/0
  |  
提交时间:2022/11/07
Key Considerations in Targeted Protein Degradation Drug Discovery and Development
期刊论文
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10
作者:
Qin, Liena
;
Dai, Han
;
Wang, Junfeng
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  |  
浏览/下载:19/0
  |  
提交时间:2022/12/23
targeted protein degradation
PROTAC
molecular glue
chemically induced proximity
drug discovery and development
Systematic Survey of the Regulatory Networks of the Long Noncoding RNA BANCR in Cervical Cancer Cells br
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2022, 卷号: 21, 期号: 4, 页码: 1137-1152
作者:
Wang, Bing
;
Wang, Min
;
Jia, Shuzhao
;
Li, Tao
;
Yang, Mingkun
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  |  
浏览/下载:0/0
  |  
提交时间:2024/05/07
long noncoding RNAs (lncRNAs)
BRAF-activated noncoding RNA (BANCR)
quantitative proteomics
cAMP regulatory element binding protein (CREB1)
miR-582-5p
Metabolomics and biochemical assays reveal the metabolic responses to hypo-salinity stress and osmoregulatory role of cAMP-PKA pathway in Mercenaria mercenaria
期刊论文
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2022, 卷号: 20, 页码: 4110-4121
作者:
Zhou, Cong
;
Song, Hao
;
Feng, Jie
;
Hu, Zhi
;
Yang, Mei-jie
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  |  
浏览/下载:0/0
  |  
提交时间:2023/12/13
Metabolomics
Osmoregulation
Oxidative stress
Energy metabolism
Hypo -salinity tolerance
Protein degradation technology: a strategic paradigm shift in drug discovery
期刊论文
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2021, 卷号: 14
作者:
Li, Haobin
;
Dong, Jinyun
;
Cai, Maohua
;
Xu, Zhiyuan
;
Cheng, Xiang-Dong
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  |  
浏览/下载:31/0
  |  
提交时间:2021/11/01
Protein degradation
Degradation pathway
Degradation technology
PROTAC
Monomeric degraders
Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 15
作者:
Lu, Shaoyong
;
He, Xinheng
;
Yang, Zhao
;
Chai, Zongtao
;
Zhou, Shuhua
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/11/04
Development of purification process for dual-function recombinant human heavy-chain ferritin by the investigation of genetic modification impact on conformation
期刊论文
ENGINEERING IN LIFE SCIENCES, 2021, 页码: 13
作者:
Yin, Shuang
;
Zhang, Bingyang
;
Lin, Jianying
;
Liu, Yongdong
;
Su, Zhiguo
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2021/08/31
ferritin E-helix turnover
ferritin genetic modification
human heavy-chain ferritin
protein characterization
protein purification
Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14
作者:
Yang, Xiangbo
;
Wang, Zhijia
;
Pei, Yuan
;
Song, Ning
;
Xu, Lei
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/08/17
SHP2 degradation
Proteolysis targeting chimera (PROTAC)
Thalidomide-based heterobifunctional molecules
E3 ubiquitin ligase
CRBN
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