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上海药物研究所 [10]
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期刊论文 [40]
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Computational discovery and biological evaluation of novel inhibitors targeting histone-lysine N-methyltransferase SET7
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 7, 页码: 10
作者:
Min, Wenjian
;
Hou, Zeng
;
Zhang, Fang
;
Xie, Shengnan
;
Yuan, Kai
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
Histone methylation
Lysine methyltransferase
SET7
Small-molecule inhibitor
Virtual screening
Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations
期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 1, 页码: 58-63
作者:
Zhu, Kongkai
;
Du, Daohai
;
Yang, Rui
;
Tao, Hongrui
;
Zhang, Hua
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  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
polycomb repressive complex 2
EZH2-EED interaction inhibitor
virtual screening
molecular dynamics simulation
Reductive methylation labeling, from quantitative to structural proteomics
期刊论文
TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2019, 卷号: 118, 页码: 771-778
作者:
Liu, Zheyi
;
Zhou, Ye
;
Liu, Jing
;
Chen, Jin
;
Heck, Albert J. R.
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  |  
浏览/下载:99/0
  |  
提交时间:2019/12/02
Reductive methylation
Stable isotope dimethyl labeling
Mass spectrometry
Quantitative proteomics
N-termini profiling
Structural proteomics
Lysine reactivity profiling
A new chromatographic approach to analyze methylproteome with enhanced lysine methylation identification performance
期刊论文
ANALYTICA CHIMICA ACTA, 2019, 卷号: 1068, 页码: 111-119
作者:
Wang, Qi
;
Liu, Zhen
;
Wang, Keyun
;
Wang, Yan
;
Ye, Mingliang
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  |  
浏览/下载:265/0
  |  
提交时间:2019/06/20
Methylproteome
Strong cation exchange
Immobilized metal ion affinity chromatography
High-pH reversed-phase chromatography
Lysine methylation identification
Prediction of ligand modulation patterns on membrane receptors via lyysine reactivity profiling
期刊论文
CHEMICAL COMMUNICATIONS, 2019, 卷号: 55, 期号: 30, 页码: 4311-4314
作者:
Zhou, Ye
;
Liu, Zheyi
;
Zhang, Jinbao
;
Dou, Tongyi
;
Chen, Jin
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  |  
浏览/下载:71/0
  |  
提交时间:2019/06/25
iAcet-Sumo: Identification of lysine acetylation and sumoylation sites in proteins by multi-class transformation methods
期刊论文
COMPUTERS IN BIOLOGY AND MEDICINE, 2018, 卷号: 100, 页码: 144-151
作者:
Yang, Yingxi
;
Wang, Hui
;
Ding, Jun
;
Xu, Yan
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  |  
浏览/下载:27/0
  |  
提交时间:2019/12/10
Identification and Characterizations of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Scaffold Hopping- and 2D-Molecular Fingerprint-Based Similarity Search
期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 3
作者:
Ding, Hong
;
Lu, Wen Chao
;
Hu, Jun Chi
;
Liu, Yu-Chih
;
Zhang, Chen Hua
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  |  
浏览/下载:50/0
  |  
提交时间:2019/01/08
SET7
inhibitor
similarity search
ligand-based drug design
chemical biology probe
H3K36 trimethylation mediated by SETD2 regulates the fate of bone marrow mesenchymal stem cells
期刊论文
PLOS BIOLOGY, 2018, 卷号: 16, 期号: 11, 页码: -
作者:
Wang, Lijun
;
Niu, Ningning
;
Li, Li
;
Sheo, Rui
;
Ouyang, Huiling
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  |  
浏览/下载:49/0
  |  
提交时间:2019/04/28
Lipopolysaccharide-binding Protein
Induced Liver-injury
Lysine 36
Histone
Differentiation
Adipogenesis
Methylation
Adipocyte
Identification
Hypb/setd2
Strategies for large-scale analysis of non-histone protein methylation by LC-MS/MS
期刊论文
ANALYST, 2017, 卷号: 142, 期号: 19, 页码: 3536-3548
作者:
Wang, Qi
;
Wang, Keyun
;
Ye, Mingliang
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  |  
浏览/下载:15/0
  |  
提交时间:2017/12/20
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