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Binding interface and impact on protease cleavage for an RNA aptamer to HIV-1 reverse transcriptase 期刊论文
NUCLEIC ACIDS RESEARCH, 2020, 卷号: 48, 期号: 5, 页码: 2709-2722
作者:  Nguyen, Phuong D. M.;  Zheng, Jie;  Gremminger, Thomas J.;  Qiu, Liming;  Zhang, Dong
收藏  |  浏览/下载:20/0  |  提交时间:2020/07/01
Design, synthesis and biological evaluation of 3-hydroxyquinazoline-2,4(1H, 3H)-diones as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and integrase 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 17, 页码: 3836-3845
作者:  Gao, Ping;  Cheng, Xiqiang;  Sun, Lin;  Song, Shu;  Alvarez, Mar
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/11
A new class of HIV-1 inhibitors and the target identification via proteomic profiling 期刊论文
SCIENCE CHINA-CHEMISTRY, 2018, 卷号: 61, 期号: 11, 页码: 1430-1439
作者:  Ge, Ying-Zi;  Zhou, Bin;  Xiao, Ruo-Xuan;  Yuan, Xiao-Jing;  Zhou, Hu
收藏  |  浏览/下载:183/0  |  提交时间:2019/01/08
Pr-957, a selective immunoproteasome inhibitor, reactivates latent hiv-1 through p-tefb activation mediated by hsf-1 期刊论文
Biochemical pharmacology, 2018, 卷号: 156, 页码: 511-523
作者:  Lin, Jian;  Zhang, Xuanxuan;  Lu, Wanzhen;  Xu, Xinfeng;  Pan, Xiaoyan
收藏  |  浏览/下载:62/0  |  提交时间:2019/05/08
HAART in HIV/AIDS Treatments: Future Trends 期刊论文
Infectious disorders drug targets, 2018, 卷号: 18, 页码: 15-22
作者:  Lu Da-Yong[1];  Wu Hong-Ying[2];  Yarla Nagendra Sastry[3];  Xu Bin[4];  Ding Jian[5]
收藏  |  浏览/下载:21/0  |  提交时间:2019/04/22
5-Hydroxypyrido[2,3-b]pyrazin-6(5H)-one derivatives as novel dual inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H and integrase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 155, 页码: 714-724
作者:  Sun, Lin;  Gao, Ping;  Dong, Guanyu;  Zhang, Xujie;  Cheng, Xiqiang
收藏  |  浏览/下载:10/0  |  提交时间:2019/12/11
Discovery of novel 3-hydroxypicolinamides as selective inhibitors of HIV-1 integrase-LEDGF/p75 interaction 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 125, 页码: 1051-1063
作者:  Zhang, Feng-Hua;  Debnath, Bikash;  Xu, Zhong-Liang;  Yang, Liu-Meng;  Song, Li-Rui
收藏  |  浏览/下载:12/0  |  提交时间:2019/01/08
Identification of spirocyclic or phosphate substituted quinolizine derivatives as novel HIV-1 integrase inhibitors: a patent evaluation of WO2016094197A1, WO2016094198A1 and WO2016154527A1 期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2017, 卷号: 27, 期号: 11, 页码: 1277-1286
作者:  Cheng, Xiqiang;  Gao, Ping;  Sun, Lin;  Tian, Ye;  Zhan, Peng
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/12
1-Hydroxypyrido[2,3-d]pyrimidin-2(1H)-ones as novel selective HIV integrase inhibitors obtained via privileged substructure-based compound libraries 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 20, 页码: 5779-5789
作者:  Gao, Ping;  Zhang, Lingzi;  Sun, Lin;  Huang, Tianguang;  Tan, Jing
收藏  |  浏览/下载:16/0  |  提交时间:2019/12/12
Study of Structure-active Relationship for Inhibitors of HIV-1 Integrase LEDGF/p75 Interaction by Machine Learning Methods 期刊论文
2017, 卷号: 36, 期号: 7
作者:  Li, Yang;  Wu, Yanbin;  Yan, Aixia
收藏  |  浏览/下载:10/0  |  提交时间:2020/01/04


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