CORC

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CORC

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Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy 期刊论文
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13
作者:  Hua, Chen;  Shena, Lijuan;  Zoua, Fengming;  Wua, Yun;  Wanga, Beilei
收藏  |  浏览/下载：10/0  |  提交时间：2023/11/10
Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14822-14847
作者:  Wei, Dan;  Wang, Hanlin;  Zeng, Qinghe;  Wang, Wenjing;  Hao, Bingbing
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16
Discovery of selective CDK9 degraders with enhancing antiproliferative activity through PROTAC conversion 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 11
作者:  Qiu, Xiaqiu;  Li, Yuanqing;  Yu, Bin;  Ren, Jie;  Huang, Huidan
收藏  |  浏览/下载：20/0  |  提交时间：2021/05/24
CDK9  Antitumor  PROTAC  AML  Degrader  
EZH2 inhibitors abrogate upregulation of trimethylation of H3K27 by CDK9 inhibitors and potentiate its activity against diffuse large B-cell lymphoma 期刊论文
HAEMATOLOGICA, 2020, 卷号: 105, 期号: 4, 页码: 1021-1031
作者:  Xie, Shao;  Wei, Fan;  Sun, Yi-ming;  Gao, Ying-lei;  Pan, Lu-lu
收藏  |  浏览/下载：38/0  |  提交时间：2020/07/01
Design of wogonin-inspired selective cyclin-dependent kinase 9 (CDK9) inhibitors with potent in vitro and in vivo antitumor activity 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 178, 页码: 782-801
作者:  Wang, Jubo;  Li, Tinghan;  Zhao, Tengteng;  Wu, Tizhi;  Liu, Chuang
收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01
Inhibition of CDK9 induces apoptosis and potentiates the effect of cisplatin in hypopharyngeal carcinoma cells 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 482, 期号: 4, 页码: 536-541
作者:  Cao, Shengda;  Yu, Yingyi;  Chen, Shangren;  Lei, Dapeng;  Wang, Shudong
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11
Antitumor action of CDK inhibitor LS-007 as a single agent and in combination with ABT-199 against human acute leukemia cells 期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 11, 页码: 1481-1489
作者:  Xie, Shao;  Jiang, Hui;  Zhai, Xiao-wen;  Wei, Fan;  Wang, Shu-dong
收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08
Cyclin-Dependent Kinase 9 Inhibition Prolongs Allograft Survival through inhibiting alloreactive CD4~+ T cells and preserving the activities of Treg Cells 会议论文
第十届全国免疫学学术大会
作者:  Yang Zhan;  Guihua Hou
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/31
Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 17, 页码: 7691-7704
作者:  Lam, Frankie;  Abbas, Abdullahi Y.;  Shao, Hao;  Teo, Theodosia;  Adams, Julian
收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08
AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation 期刊论文
http://dx.doi.org/10.1073/pnas.1318503111, 2014
Lu, Huasong; Li, Zichong; Xue, Yuhua; Schulze-Gahmen, Ursula; Johnson, Jeffrey R.; Krogan, Nevan J.; Alber, Tom; Zhou, Qiang; 薛玉花; 周强
收藏  |  浏览/下载：3/0  |  提交时间：2015/07/22

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