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厦门大学 [1]
西北高原生物研究所 [1]
新疆理化技术研究所 [1]
中南大学 [1]
华中师范大学 [1]
武汉大学 [1]
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期刊论文 [9]
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Shabyar Ameliorates High Glucose Induced Retinal Pigment Epithelium Injury Through Suppressing Aldose Reductase and AMPK/mTOR/ULK1 Autophagy Pathway
期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 期号: 5, 页码: 1-15
作者:
Liu, XY (Liu, Xiao Yan) [1] , [2] , [3]
;
Peng, J (Peng, Jun) [1] , [2]
;
He, F (He, Fei) [1]
;
Tursun, X (Tursun, Xirali) [4]
;
Li, SP (Li, Shu Ping) [1]
收藏
  |  
浏览/下载:129/0
  |  
提交时间:2022/06/06
shabyar
retinal pigment epithelium
autophagy
aldose reductase
traditional medicine formula
Down-regulation of BCL2L13 renders poor prognosis in clear cell and papillary renal cell carcinoma
期刊论文
CANCER CELL INTERNATIONAL, 2021, 卷号: 21
作者:
Meng, Fei
;
Zhang, Luojin
;
Zhang, Mingjun
;
Ye, Kaiqin
;
Guo, Wei
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  |  
浏览/下载:33/0
  |  
提交时间:2021/08/31
BCL-rambo
Cell death
Renal cancer
Prognosis
ANT
Anthocyanins from Lycium ruthenicum Murr. Ameliorated D-Galactose-Induced Memory Impairment, Oxidative Stress, and Neuroinflammation in Adult Rats
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 11
作者:
Chen, Shasha
;
Zhou, Haonan
;
Zhang, Gong
;
Meng, Jing
;
Deng, Kai
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  |  
浏览/下载:50/0
  |  
提交时间:2019/11/26
Lycium ruthenicum Murr
anthocyanins
oxidative stress
memory impairment
neuroinflammation
neurodegeneration
Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
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  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Taraxasterol suppresses the growth of human liver cancer by upregulating Hint1 expression
期刊论文
Journal of Molecular Medicine, 2018, 期号: 96, 页码: 661–672
作者:
Tianhao Bao
;
Chunjie Xiao
;
Yifan Wang
;
Weiwei Wang
;
Yuehua Li
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2018/09/19
Taraxasterol
Hint1
Cellproliferation
Cellcycle
Apoptosis
Livercancer
Expression pattern and functional analysis of fundc1 in rare minnow (Gobiocypris rarus)
期刊论文
Gene, 2017, 卷号: 626, 页码: 149-157
作者:
Xu, Gongyu
;
Li, Zhenzhen
;
Xiao, Jinwen
;
Li, Fangqing
;
Ye, Weiyuan
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/23
Fundc1
Fun14 domain-containing protein 1
MAM
mitochondrial-associated membrane
CANX
calnexin
LC3B
microtubule-associated protein 1 light chain 3 beta
BNIP3
BCL2/adenovirus E1B interacting protein 3
BNIP3L
BCL2/adenovirus E1B interacting protein 3-like
LIR
LC3-interacting region
TM
transmembrane
CK2
casein kinase 2
RACE
rapid amplification of cDNA ends
NCBI
National Center for Biotechnology Information
UTR
untranslated region
ORF
open reading frame
Rare minnow
Fundc1
Embryogenesis
Hypoxia
MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals
期刊论文
AUTOPHAGY, 2015, 卷号: 11, 期号: 7
作者:
Yuan, Jia
;
Zhang, Ying
;
Sheng, Yue
;
Fu, Xiazhou
;
Cheng, Hanhua
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Beclin1
MYBL2
ovary
reproduction
transcription regulation
VDAC2
ATG5
autophagy-related 5
ATG12
autophagy-related 12
ATG16L1
autophagy-related 16-like 1
BAK
BCL2-antagonist
killer 1
BCL2
B-cell CLL
lymphoma 2
BCL2L1
BCL2-like 1
BECN1
Beclin 1
autophagy related
CDS
coding DNA sequence
Dpp
days postpartum
GATA1
GATA binding protein 1 (globin transcription factor 1)
GATA2
GATA binding protein 2
LC3B
microtubule-associated protein 1 light chain 3 beta
MBS
MYBL2 binding site
MYBL2
v-myb avian myeloblastosis viral oncogene homolog-like 2
SP1
Sp1 transcription factor
VDAC
voltage-dependent anion channel
wt
wild type
The FoxO-BNIP3 axis exerts a unique regulation of mTORC1 and cell survival under energy stress
期刊论文
http://dx.doi.org/10.1038/onc.2013.273, 2014
Lin, A.
;
Yao, J.
;
Zhuang, L.
;
Wang, D.
;
Han, J.
;
Lam, E. W-F
;
Gan, B.
;
韩家淮
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2015/07/22
TSC1-TSC2 COMPLEX
TUMOR SUPPRESSORS
SIGNALING PATHWAY
MAMMALIAN TARGET
GROWTH-CONTROL
NULL-CELLS
AMPK
METABOLISM
LKB1
AUTOPHAGY
Se-Methylselenocysteine Inhibits Apoptosis Induced by Clusterin Knockdown in Neuroblastoma N2a and SH-SY5Y Cell Lines
期刊论文
international journal of molecular sciences, 2014, 卷号: 15, 期号: 11, 页码: 21331-21347
Wang, Chao
;
Zeng, Zhenyu
;
Liu, Qiong
;
Zhang,Renli
;
Ni,Jiazuan
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2015/10/21
STRESS-INDUCED APOPTOSIS
GENOME-WIDE ASSOCIATION
OXIDATIVE STRESS
ALZHEIMERS-DISEASE
CLUSTERIN/APOLIPOPROTEIN-J
IDENTIFIES VARIANTS
DEATH
CANCER
EXPRESSION
PROTEIN
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