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水生生物研究所 [15]
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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Chemerin reverses the malignant phenotype and induces differentiation of human hepatoma SMMC7721 cells
期刊论文
ARCHIVES OF PHARMACAL RESEARCH, 2021, 卷号: 44, 期号: 2
作者:
Li, Ming
;
Sun, Pengcheng
;
Dong, Kaikai
;
Xin, Ye
;
TaiLulu, Aslee
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  |  
浏览/下载:18/0
  |  
提交时间:2021/11/18
Chemerin
Human hepatic carcinoma SMMC7721 cells
Cell proliferation
Malignant phenotype
Cell differentiation
海豚链球菌诱导的牙鲆microRNA表达、调控及功能研究
学位论文
中国科学院海洋研究所: 中国科学院大学, 2020
作者:
刘爽
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/06/16
Microrna,牙鲆,海豚链球菌,双特异性磷酸酶dusp6,fas介导的凋亡抑制因子faim1
Endosulfan promotes cell migration via PTP4A3-mediated signaling pathways in HUVECs
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 192, 页码: 1-9
作者:
Li, Heng
;
Liu, Shiqi
;
Hu, Yumeng
;
Zhao, Bin
;
Sun, Yeqing
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/09/14
Endosulfan
Cell migration
PTP4A3
Signaling pathway
Endothelial cells
Transcriptomic profile of oyster Crassostrea gigas hemocyte after short-term cadmium exposure and bacteria stimulation
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2020, 卷号: 98, 页码: 138-146
作者:
Qiu, Limei
;
Chen, Hao
;
Zhou, Zhi
;
Zhang, Huan
;
Liu, Rui
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  |  
浏览/下载:30/0
  |  
提交时间:2020/09/23
Crassostrea gigas
Cadmium exposure
Bacteria challenge
Immune response
Neuro-endocrine-immune regulatory network
Characterization of Streptococcus iniae-induced microRNA profiles in Paralichthys olivaceus and identification of pol-3p-10740_175 as a regulator of antibacterial immune response
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2020, 卷号: 98, 页码: 860-867
作者:
Liu, Shuang
;
Ning, Xian-hui
;
Guan, Xiao-lu
;
Li, Xue-peng
;
Sun, Li
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/09/23
Streptococcus iniae
Paralichthys olivaceus
miRNA
High-throughput sequencing
Immune response
Evaluation of selected traditional Chinese medical extracts for bone mineral density maintenance: A mechanistic study.
期刊论文
Journal of traditional and complementary medicine, 2019, 卷号: 9, 期号: 3
作者:
Rebhun John F
;
Du Qin
;
Hood Molly
;
Guo Hailing
;
Glynn Kelly M
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/12/05
Anti-inflammatory
BMD, bone mineral density
BSA, bovine serum albumin
Bmp4, bone morphogenic protein 4
CRE, cyclic adenosine monophosphate response element
CREB, cyclic adenosine monophosphate response element binding protein
DEXA, dual-energy X-ray absorptiometry
DMSO, Dimethyl sulfoxide
Drynaria fortunei
E2, estradiol
ER, estrogen receptor
ERE, estrogen response element
Epimedium brevicornu
Estrogenic
FBS, fetal bovine serum
Fsk, forskolin
Hprt, hypoxanthine-guanine phosphoribosyl-transferase
IL-1, interleukin 1
LBD, ligand binding domain
LBM, low bone mass
M-CSF, macrophage colony-stimulating factor
MAPK, mitogen activated protein kinase
NF-κβ, nuclear factor kappa beta
OP, osteoporosis
Osteoporosis
PTH, parathyroid hormone
PTHrp, PTH related peptide
RANKL, receptor activator of nuclear factor kappa beta ligand
RLU, relative luminescence unit
ROI, region of interest
Runx2, runt-related transcription factor 2
SFM, serum free media
TCM, traditional Chinese medicine
TNFα, tumor necrosis factor alpha
TRAP, tartrate-resistant acid phosphatase
UAS, upstream activating sequence
cAMP, cyclic adenosine monophosphate
qPCR, quantitative polymerase chain reaction
HoxA10 Facilitates SHP-1-Catalyzed Dephosphorylation of p38 MAPK/STAT3 To Repress Hepatitis B Virus Replication by a Feedback Regulatory Mechanism
期刊论文
JOURNAL OF VIROLOGY, 2019, 卷号: 93, 期号: 7
作者:
Yang, Qingyu
;
Zhang, Qi
;
Zhang, Xuewu
;
You, Lei
;
Wang, Wenbiao
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/05
hepatitis B virus infection and pathogenesis
homeobox protein A10
HoxA10
SH2-containing protein tyrosine phosphatase 1
SHP-1
signal transducer and activator of transcription 3
p38 MAPK-STAT3 signaling pathway
mitogen-activated protein kinase
A Novel Rhein Derivative Modulates Bone Formation and Resorption and Ameliorates Estrogen-Dependent Bone Loss
期刊论文
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2018
作者:
Jiang, Min
;
Wang, Tianqi
;
Yan, Xueming
;
Liu, Zhuochao
;
Yan, Yufei
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  |  
浏览/下载:95/0
  |  
提交时间:2019/01/08
Dietary magnesium deficiency impaired intestinal structural integrity in grass carp (Ctenopharyngodon idella)
期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8, 期号: 1, 页码: 20
作者:
Wei, Shuo-Peng
;
Jiang, Wei-Dan
;
Wu, Pei
;
Liu, Yang
;
Zeng, Yun-Yun
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/07/02
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