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上海药物研究所 [6]
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大连理工大学 [1]
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昆明植物研究所 [1]
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期刊论文 [13]
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Virtual Screening for Type II B Inhibitors of B-Raf(V600E) Kinase
期刊论文
CURRENT COMPUTER-AIDED DRUG DESIGN, 2020
作者:
Qiu, Kai-Xiong
;
Zhang, Wen
;
Yu, Fang
;
Li, Wei
;
Sun, Zhong-Wen
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/01/05
Design and discovery of thioether and nicotinamide containing sorafenib analogues as multikinase inhibitors targeting B-Raf, B-Raf(V600E) and VEGFR-2
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 9, 页码: 2381-2391
作者:
Sun, Shaofeng
;
He, Zuopeng
;
Huang, Mindong
;
Wang, Ningning
;
He, Zongzhong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
Nicotinamide
B-Raf
VEGFR-2
Kinase inhibitor
Antitumor
AKT is critically involved in the antagonism of BRAF inhibitor sorafenib against dabrafenib in colorectal cancer cells harboring both wild-type and mutant (V600E) BRAF genes
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 489, 期号: 1, 页码: 14-20
作者:
Wang, Hongbin
;
Quan, Haitian
;
Lou, Liguang
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Antagonism
AKT
BRAF
Dabrafenib
Sorafenib
Docking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-Raf(V600E) inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1059-1068
作者:
Wang, Gui-min
;
Wang, Xiang
;
Zhu, Jian-ming
;
Guo, Bin-bin
;
Yang, Zhuo
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
B-Raf(V600E) inhibitor
anticancer
vemurafenib
deazapurine
fragment reassembly
molecular docking
structure-activity relationship
Association between BRAF(V600E) mutation and the clinicopathological features of solitary papillary thyroid microcarcinoma
期刊论文
2017, 卷号: 13, 期号: 3, 页码: 1595-1600
作者:
Lu, Hai-Zhen
;
Qiu, Tian
;
Ying, Jian-Ming
;
Lyn, Ning
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/04
solitary papillary thyroid micro-carcinoma
B-Raf proto-oncogene serine/threonine kinase mutation
clinicopathological features
autoimmune thyroiditis
prognosis
Braf gene: from human cancers to developmental syndromes
期刊论文
Saudi journal of biological sciences, 2015, 卷号: 22, 期号: 4, 页码: 359-373
作者:
Hussain, Muhammad Ramzan Manwar
;
Baig, Mukhtiar
;
Mohamoud, Hussein Sheik Ali
;
Ulhaq, Zaheer
;
Hoessli, Daniel C.
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/05/10
Braf gene
Ras-raf overactivation
Cancers
Developmental syndromes
Insight into the Structural Features of Pyrazolopyrimidine- and Pyrazolopyridine-based B-Raf(V600E) Kinase Inhibitors by Computational Explorations
期刊论文
chemical biology & drug design, 2014, 卷号: 83, 期号: 6, 页码: 643-655
作者:
Li, Yan
;
Han, Chunxiao
;
Wang, Jinghui
;
Yang, Yinfeng
;
Zhang, Jingxiao
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2015/11/17
B-Raf(V600E) kinase
Pyrazolopyrimidine- and pyrazolopyridine-based inhibitors
3D-QSAR
docking
md
The B-Raf(V600E) inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury
期刊论文
CELL DEATH & DISEASE, 2014, 卷号: 5
作者:
Li, J-X
;
Feng, J-M
;
Wang, Y.
;
Li, X-H
;
Chen, X-X
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Insight into the Structural Features of Pyrazolopyrimidine- and Pyrazolopyridine-based B-Raf(V600E) Kinase Inhibitors by Computational Explorations
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2014, 卷号: 83, 页码: 643-655
作者:
Li, Yan
;
Han, Chunxiao
;
Wang, Jinghui
;
Yang, Yinfeng
;
Zhang, Jingxiao
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/09
B-Raf(V600E) kinase
Pyrazolopyrimidine- and pyrazolopyridine-based inhibitors
3D-QSAR
docking
md
Identification and synthesis of N-(thiophen-2-yl) benzamide derivatives as BRAF(V600E) inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 8, 页码: 2306-2312
作者:
Xie, Yunfeng
;
Chen, Xianjie
;
Qin, Jie
;
Kong, Xiangqian
;
Ye, Fei
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/01/08
BRAF
Kinase inhibitors
Virtual screening
Anticancer agents
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