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上海药物研究所 [46]
北京大学 [39]
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厦门大学 [14]
山东大学 [11]
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Optimization and Development of a Scalable Palladium-Catalyzed C-H Activation Process for the Geometry-Selective Preparation of Kilograms of YLF466D, a Potent AMP-Activated Protein Kinase Activator
期刊论文
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 10, 页码: 2260-2269
作者:
Yin, Jianpeng
;
Zhan, Desheng
;
Ma, Hui
;
Liu, Huanan
;
Yu, Lifang
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/12/16
YLF466D
AMPK activator
glucose metabolism
lipid metabolism
MIRI
domino reaction
C-H activation
Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK
期刊论文
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 19, 页码: 2243-2263
作者:
Elksnis, Andris
;
Schiffer, Tomas A.
;
Palm, Fredrik
;
Wang, Yun
;
Cen, Jing
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  |  
浏览/下载:22/0
  |  
提交时间:2021/12/01
Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function
期刊论文
CELL RESEARCH, 2021, 页码: 18
作者:
Xu, Xiang
;
Ding, Guangjin
;
Liu, Caizhi
;
Ding, Yuhan
;
Chen, Xiaoxin
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  |  
浏览/下载:63/0
  |  
提交时间:2021/11/04
Cytoplasmic DNA sensing by KU complex in aged CD4(+) T cell potentiates T cell activation and aging-related autoimmune inflammation
期刊论文
IMMUNITY, 2021, 卷号: 54, 期号: 4, 页码: 632-+
作者:
Wang, Yan
;
Fu, Zunyun
;
Li, Xutong
;
Liang, Yinming
;
Pei, Siyu
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  |  
浏览/下载:61/0
  |  
提交时间:2021/06/11
Effects of dibutyl phthalate on lipid metabolism in liver and hepatocytes based on PPAR alpha/SREBP-1c/FAS/GPAT/AMPK signal pathway
期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2021, 卷号: 149
作者:
Zhang, Wang
;
Li, Jing-Ya
;
Wei, Xiao-Chen
;
Wang, Qian
;
Yang, Ji-Yang
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  |  
浏览/下载:58/0
  |  
提交时间:2021/04/26
DBP
PPAR alpha
AMPK
Lipid metabolism
Liver function
DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation
期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69
作者:
Lv, Jianlu
;
Wang, Wei
;
Zhu, Xialin
;
Xu, Xiaoju
;
Yan, Qiuying
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/12/21
Alzheimer'sdisease
Microglia
AMPK alpha 1
DW14006
Phagocytosis
Neuro-inflammation
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2020, 卷号: 404, 页码: 14
作者:
Wang, Ying
;
Zhu, Yao
;
Niu, Junxing
;
Deng, Qiangqiang
;
Guo, Shimeng
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  |  
浏览/下载:60/0
  |  
提交时间:2020/12/21
Bile acid analog
NASH
TGR5
Cd36
AMPK alpha
Non-thermal plasma with metformin synergistically induces cell death via upregulating AMPK to suppress energy metabolism
期刊论文
JOURNAL OF PHYSICS D-APPLIED PHYSICS, 2020, 卷号: 53
作者:
Cui, Shujun
;
Chen, Guodong
;
Yu, K. N.
;
Cheng, Cheng
;
Han, Wei
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  |  
浏览/下载:18/0
  |  
提交时间:2020/11/26
non-thermal plasma
metformin
AMP-activated protein kinase
energy metabolism
Pyrazolone derivative C29 protects against HFD-induced obesity in mice via activation of AMPK in adipose tissue
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Li, Bo-han
;
Zhang, Mei
;
Duan, Ya-nan
;
Shuai, Lin
;
Jiang, Hao-wen
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2020/12/21
AMP-activated protein kinase
pyrazolone derivative C29
obesity
energy expenditure
thermogenesis
inguinal white adipose tissue
white adipose browning
Notoginsenoside R1 attenuates sevoflurane-induced neurotoxicity
期刊论文
TRANSLATIONAL NEUROSCIENCE, 2020, 卷号: 11, 期号: 1, 页码: 215-226
作者:
Zhang, Yibing
;
Zhao, Yong
;
Ran, Yongwang
;
Guo, Jianyou
;
Cui, Haifeng
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/08/03
5 '-AMP-activated protein kinase
neurotoxicity
notoginsenoside R1
sevoflurane
sestrin-2
reactive oxygen species
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