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科研机构
上海药物研究所 [52]
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期刊论文 [52]
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2021 [3]
2020 [10]
2019 [4]
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STING inhibitor ameliorates LPS-induced ALI by preventing vascular endothelial cells-mediated immune cells chemotaxis and adhesion
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Wu, Bing
;
Xu, Meng-meng
;
Fan, Chen
;
Feng, Chun-lan
;
Lu, Qiu-kai
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/01/18
acute lung injury
STING
vascular endothelial cells
inflammatory cytokines
chemokines
chemotaxis
Synthesis and Structure-Activity Relationships of Ring-Opened Bengamide Analogues against Methicillin-Resistant Staphylococcus aureus(dagger)
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 3, 页码: 671-676
作者:
Yu, Chen-Xi
;
Wei, Bing-Yan
;
Kong, Xue-Qing
;
Yang, Cai-Guang
;
Nan, Fa-Jun
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/05/24
Bengamides
Staphylococcus aureus
Antibiotics
Structure‐
activity relationships
Pharmacokinetic
Rhodium-Catalyzed Twofold Unsymmetrical C-H Alkenylation-Annulation/Thiolation Reaction To Access Thiobenzofurans
期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 4, 页码: 1194-1198
作者:
Lin, Jian
;
Hu, Liuyu
;
Chen, Chao
;
Feng, Huijin
;
Yu, Yang
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2021/05/24
Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7
作者:
Bi, Xiaoyang
;
Chen, Yu
;
Sun, Zhongya
;
Lu, Wenchao
;
Xu, Pan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
Drug design
CBP
Bromodomain
Inhibitor
Acute myeloid leukemia
Metabolic modulation via mTOR pathway and anti-angiogenesis remodels tumor microenvironment using PD-L1-targeting codelivery
期刊论文
BIOMATERIALS, 2020, 卷号: 255, 页码: 12
作者:
Chen, Binfan
;
Gao, Ang
;
Tu, Bin
;
Wang, Yonghui
;
Yu, Xiaolu
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/12/24
Tumor-associated macrophage
Glycolysis
mTOR
Angiogenesis
Tumor immune microenvironment
Liposome
Extracellular Vesicle-Mediated Delivery of Circular RNA SCMH1 Promotes Functional Recovery in Rodent and Nonhuman Primate Ischemic Stroke Models
期刊论文
CIRCULATION, 2020, 卷号: 142, 期号: 6, 页码: 556-574
作者:
Yang, Li
;
Han, Bing
;
Zhang, Zhiting
;
Wang, Shuguo
;
Bai, Ying
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2020/12/24
circular RNA
extracellular vesicles
MeCP2 protein
neuronal plasticity
primate
stroke
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:
Chen, Yu
;
Bi, Xiaoyang
;
Zhang, Fengcai
;
Sun, Zhongya
;
Xu, Pan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/12/24
In silico screening
Drug design
CBP
Bromodomain
Inhibitor
Acute Myeloblastic Leukemia
A potential drug combination of omeprazole and patchouli alcohol significantly normalizes oxidative stress and inflammatory responses against gastric ulcer in ethanol-induced rat model
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2020, 卷号: 85, 页码: 9
作者:
Xie, Lu
;
Guo, Yi-lin
;
Chen, Yu-rou
;
Zhang, Li-ying
;
Wang, Zhi-cheng
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/12/24
Gastric ulcer
Omeprazole
Patchouli alcohol
Design, Synthesis and Biological Evaluation of Bengamide Analogues as ClpP Activators
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2020, 页码: 5
作者:
Kong, Xue-Qing
;
Wei, Bing-Yan
;
Yu, Chen-Xi
;
Guan, Xiang-Na
;
Ma, Wei-Ping
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/12/24
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma
期刊论文
JOURNAL OF HEPATOLOGY, 2020, 卷号: 72, 期号: 5, 页码: 896-908
作者:
Dong, Liang-qing
;
Peng, Li-hua
;
Ma, Li-jie
;
Liu, Dong-bing
;
Zhang, Shu
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2020/07/01
Hepatocellular carcinoma
Tumor heterogeneity
Tumor microenvironment
Immunoediting
Neoantigen
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