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CORC

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SN38-based albumin-binding prodrug for efficient targeted cancer chemotherapy 期刊论文
JOURNAL OF CONTROLLED RELEASE, 2021, 卷号: 339, 页码: 297-306
作者:  Huang, Ying;  Wang, Lei;  Cheng, Zhiyang;  Yang, Biyu;  Yu, Jiahui
收藏  |  浏览/下载：24/0  |  提交时间：2021/12/01
Combating liver cancer through GO-targeted biomaterials 期刊论文
BIOMEDICAL MATERIALS, 2021, 卷号: 16, 期号: 6, 页码: 14
作者:  Huang, Xing;  Zhang, Jiaxin;  Song, Yijie;  Zhang, Tong;  Wang, Bing
收藏  |  浏览/下载：62/0  |  提交时间：2021/11/04
A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor 期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8
作者:  Zhou, Jun;  Zhan, Yan;  Zhong, Dafang;  Chen, Xiaoyan;  Zhang, Yifan
收藏  |  浏览/下载：72/0  |  提交时间：2021/11/04
Design and synthesis of novel desfluoroquinolone-aminopyrimidine hybrids as potent anti-MRSA agents with low hERG activity 期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 103, 页码: 10
作者:  Song, Runzhe;  Wang, Yue;  Wang, Minghui;  Gao, Ruixuan;  Yang, Teng
收藏  |  浏览/下载：24/0  |  提交时间：2020/12/24
Design, Synthesis, and Biological Evaluation of HSP90 Inhibitor-SN38 Conjugates for Targeted Drug Accumulation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 10, 页码: 5421-5441
作者:  Zhu, Shulei;  Shen, Qianqian;  Gao, Yinglei;  Wang, Lei;  Fang, Yanfen
收藏  |  浏览/下载：8/0  |  提交时间：2020/12/24
Co-Prodrugs of 7-Ethyl-10-hydroxycamptothecin and Vorinostat with in Vitro Hydrolysis and Anticancer Effects 期刊论文
ACS OMEGA, 2020, 卷号: 5, 期号: 1, 页码: 350-357
作者:  Liu, Shuangxi;  Hu, Zonglong;  Zhang, Qiumeng;  Zhu, Qiwen;  Chen, Yi
收藏  |  浏览/下载：12/0  |  提交时间：2020/07/01
Design, Synthesis, and Biological Evaluation of Novel DNA Gyrase-Inhibiting Spiropyrimidinetriones as Potent Antibiotics for Treatment of Infections Caused by Multidrug-Resistant Gram-Positive Bacteria 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 2950-2973
作者:  Shi, Chenghui;  Zhang, Yinyong;  Wang, Ting;  Lu, Wenchao;  Zhang, Shuhua
收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01
Synthesis and In Vitro Antitumor Activity of Novel Bivalent -Carboline-3-carboxylic Acid Derivatives with DNA as a Potential Target 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 10
作者:  Gu, Hongling;  Li, Na;  Dai, Jiangkun;  Xi, Yaxi;  Wang, Shijun
收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08
A series of camptothecin prodrugs exhibit HDAC inhibition activity 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 16, 页码: 4706-4715
作者:  Zhu, Qiwen;  Yu, Xumeng;  Shen, Qianqian;  Zhang, Qiumeng;  Su, Mingbo
收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08
New tanshinone I derivatives S222 and S439 similarly inhibit topoisomerase I/II but reveal different p53-dependency in inducing G2/M arrest and apoptosis 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 154, 页码: 255-264
作者:  Tian, Qian-Ting;  Ding, Chun-Yong;  Song, Shan-Shan;  Wang, Ying-Qing;  Zhang, Ao
收藏  |  浏览/下载：42/0  |  提交时间：2019/01/08

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