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科研机构
上海药物研究所 [30]
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期刊论文 [30]
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2021 [4]
2020 [3]
2019 [2]
2018 [1]
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Pharmacolo... [2]
Chemistry [1]
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A general strategy to the intracellular sensing of glycosidases using AIE-based glycoclusters
期刊论文
CHEMICAL SCIENCE, 2021, 卷号: 13, 期号: 1, 页码: 247-256
作者:
Dong, Lei
;
Zhang, Min-Yu
;
Han, Hai-Hao
;
Zang, Yi
;
Chen, Guo-Rong
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  |  
浏览/下载:29/0
  |  
提交时间:2022/01/18
Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel alpha-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 17
作者:
Xie, Hong-Xu
;
Zhang, Juan
;
Li, Yue
;
Zhang, Jin-He
;
Liu, Shan-Kui
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  |  
浏览/下载:68/0
  |  
提交时间:2021/11/04
Tetrahydrobenzo[b]thiophen-2-yl)urea
alpha-Glucosidase inhibitors
Non-competitive inhibitor
Molecular docking
Anti-hyperglycaemic activity
Type 2 diabetes
Qualitatively and quantitatively investigating the metabolism of 20(S)-protopanaxadiol-type ginsenosides by gut microbiota of different species
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2021, 页码: 8
作者:
Zhang, Ying
;
Yao, Lingling
;
Tang, Chunping
;
Jiang, Jianlan
;
Ye, Yang
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  |  
浏览/下载:44/0
  |  
提交时间:2021/11/04
gut microbiota
LC-MS
PPD-type ginsenosides
species
Discovery of New alpha-Glucosidase Inhibitors: Structure-Based Virtual Screening and Biological Evaluation
期刊论文
FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 9
作者:
Liu, Shan-Kui
;
Hao, Haifang
;
Bian, Yuan
;
Ge, Yong-Xi
;
Lu, Shengyuan
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  |  
浏览/下载:59/0
  |  
提交时间:2021/05/24
α
-glycosidase
virtual screening
cytotoxicity
type 2 diabetes
molecular docking
Determination of the antidiabetic chemical basis of Phellodendri Chinensis Cortex by integrating hepatic disposition in vivo and hepatic gluconeogenese inhibition in vitro
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 263, 页码: 10
作者:
Tian, Xiaoting
;
Xu, Zhou
;
Hu, Pei
;
Yu, Yanyan
;
Li, Zhixiong
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  |  
浏览/下载:73/0
  |  
提交时间:2020/12/21
Phellodendri Chinensis cortex
Hepatic disposition
Pharmacokinetics
Berberine
Metabolites
Hepatic gluconeogenesis
New cembrane-type diterpenoids from the South China Sea soft coral Sinularia crassa and their alpha-glucosidase inhibitory activity
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 104, 页码: 6
作者:
Wu, Meng-Jun
;
Wang, Hong
;
Jiang, Cheng-Shi
;
Guo, Yue-Wei
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  |  
浏览/下载:8/0
  |  
提交时间:2021/05/24
Sinularia crassa
Cembranoid
Modified Mosher's method
ECD calculation
alpha-Glucosidase inhibitor
Asperbutenolide A, an unusual aromatic butenolide dimer with diverse bioactivities from a marine-derived fungus Aspergillus terreus SCAU011
期刊论文
TETRAHEDRON LETTERS, 2020, 卷号: 61, 期号: 32, 页码: 6
作者:
Bao, Jie
;
Li, Xiu-Xiu
;
He, Fei
;
Zhang, Xiaoyong
;
Zhu, Kongkai
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  |  
浏览/下载:15/0
  |  
提交时间:2020/12/24
Aspergillus terreus
Asperbutenolide A
Butyrolactone
Butenolide
A comprehensive study of pomegranate flowers polyphenols and metabolites in rat biological samples by high-performance liquid chromatography quadrupole time-of-flight mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2019, 卷号: 1604, 页码: 13
作者:
Yisimayili, Zainaipuguli
;
Abdulla, Rahima
;
Tian, Qiang
;
Wang, Yangyang
;
Chen, Mingcang
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  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Punica granatum L. flowers
Polyphenols
Ellagitannin
Metabolism
HPLC-Q-TOF-MS2
Frondoplysins A and B, Unprecedented Terpene-Alkaloid Bioconjugates from Dysidea frondosa
期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 16, 页码: 6190-6193
作者:
Jiao, Wei-Hua
;
Li, Jing
;
Zhang, Meng-Meng
;
Cui, Jie
;
Gui, Yu-Han
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  |  
浏览/下载:2/0
  |  
提交时间:2020/07/01
Isolation, identification and bioactivities of abietane diterpenoids from Premna szemaoensis
期刊论文
RSC ADVANCES, 2018, 卷号: 8, 期号: 12, 页码: 6425-6435
作者:
Pu, De-Bing
;
Wang, Ting
;
Zhang, Xing-Jie
;
Gao, Jun-Bo
;
Zhang, Rui-Han
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  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
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