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科研机构
上海药物研究所 [35]
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期刊论文 [35]
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2021 [5]
2019 [2]
2018 [6]
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An enhanced strategy integrating offline two-dimensional separation with data independent acquisition mode and deconvolution: Characterization of metabolites of Uncaria rhynchophylla in rat plasma as a case
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 卷号: 1181, 页码: 8
作者:
Li, Haojv
;
Wei, Wenlong
;
Li, Zhenwei
;
Wang, Mengyuan
;
Wei, Xuemei
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/11/04
Off-line 2D separation system
Metabolites characterization in vivo
Data independent acquisition
Multi-dimensional deconvolution
Uncaria rhynchophylla
Absorption, distribution, metabolism, and excretion of [C-14]NBP (3-n-butylphthalide) in rats
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 卷号: 1181, 页码: 9
作者:
Tian, Junjun
;
Lei, Peng
;
He, Yifei
;
Zhang, Ning
;
Ge, Xinyu
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/11/04
3-n-butylphthalide (NBP)
[C-14]NBP
Pharmacokinetics
Tissue distribution
Metabolism
Mass balance
A systematic strategy integrating solid-phase extraction, full scan range splitting, mass defect filter and precursor ion list for comprehensive metabolite profiling of Danqi Tongmai tablet in rats
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 9
作者:
Li, Zhen-wei
;
Wei, Wen-long
;
Li, Hao-jv
;
Wu, Shi-fei
;
Huang, Yong
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2021/05/24
Metabolite profiling
Solid-phase extraction
Mass defect filter
Precursor ion list
Danqi Tongmai tablet
Exploration of tissue distribution of ginsenoside Rg1 by LC-MS/MS and nanospray desorption electrospray ionization mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 7
作者:
Wei, Wenlong
;
Li, Zhenwei
;
Li, Haojv
;
An, Yaling
;
Qu, Hua
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/05/24
Ginsenoside Rg1
Nanospray desorption electrospray ionization
Tissue distribution
Spatial distribution
Comprehensive evaluation of NAODESHENG by combining UPLC quantitative fingerprint and antioxidant activity
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 193, 页码: 7
作者:
Liao, Jun-cheng
;
Wu, Yun-shan
;
Xu, Fang-fang
;
Chen, Wei-ying
;
Zheng, Zuo-liang
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/05/24
Determination of content
NAODESHENG
Multi-wavelength fusion fingerprint
Anti-oxidation
Traditional Chinese Medicine (TCM)
Simultaneous determination of imrecoxib and its two active metabolites in plasma of hepatic impairment patients by liquid chromatography-tandem mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2019, 卷号: 1122, 页码: 58-63
作者:
Hou, Xiangyu
;
Dai, Xiaojian
;
Yang, Yong
;
Zhang, Yifan
;
Zhong, Dafang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
Imrecoxib
Imrecoxib active metabolites
Pharmacokinetics
LC-MS/MS
Human
Moderate impairment
Study on the herb-herb interaction of Danqi Tongmai Tablet based on the pharmacokinetics of twelve notoginsenoides in acute myocardial ischemia and sham rats
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 166, 页码: 52-65
作者:
Zhi, Haijuan
;
Deng, Yanping
;
Yan, Bingpeng
;
Li, Zhenwei
;
Han, Sumei
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
Danqi Tongmai tablet
Herb-herb interaction
Acute myocardial ischemic
UHPLC-TQ/MS
Pharmacokinetics
Comparative study of chemical composition and active components against α-glucosidase of various medicinal parts of Morus alba L
期刊论文
Biomedical chromatography : BMC, 2018, 卷号: 32, 期号: 11, 页码: e4328
作者:
Chen, Zhiyong
;
Du, Xia
;
Yang, Yuanyuan
;
Cui, Xiaomin
;
Zhang, Zijia
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
Establishment and application of a new HPLC qualitative and quantitative assay for Gentiana Macrophyllae Radix based on characteristic constituents of anofinic acid and its derivatives
期刊论文
Biomedical chromatography : BMC, 2018, 卷号: 32, 期号: 11, 页码: e4341
作者:
Ding, Wenzheng
;
Wang, Hanxue
;
Zhou, Quan
;
Wu, Jinrong
;
Cheng, Xuemei
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Simultaneous determination of isochamaejasmin, neochamaejasmin A and aphnoretinin rat plasma by UPLC-MS/MS and its application to a pharmacokinetic study of Stellera chamaejasme L. extract
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2018, 卷号: 32, 期号: 5
作者:
Wang, Ludi
;
Yang, Wei
;
Wu, Siyang
;
Wang, Shuyao
;
Kang, Chen
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
daphnoretin
isochamaejasmin
neochamaejasmin A
pharmacokineitc study
Stellera chamaejasme L
UPLC-MS
MS
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