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科研机构
昆明植物研究所 [9]
南海海洋研究所 [2]
海洋研究所 [1]
昆明动物研究所 [1]
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期刊论文 [13]
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学科主题:Chemistry, Medicinal
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Design, Synthesis and Biological Evaluation of Caudatin Analogs as Potent Hepatitis B Virus Inhibitors
期刊论文
MEDICINAL CHEMISTRY, 2015, 卷号: 11, 期号: 2, 页码: 165-179
作者:
Wang, Li-Jun
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浏览/下载:18/0
  |  
提交时间:2015/06/29
Anti-HBV activity
Caudatin analogs
Hepatitis B e Antigen (HBeAg)
Hepatitis B Surface Antigen (HBsAg)
HBV DNA replication
Structure-activity relationships(SARs)
Synthesis
Synthesis and cytotoxic activity of novel hybrid compounds between 2-alkylbenzofuran and imidazole
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2014, 卷号: 23, 期号: 3, 页码: 1599-1611
作者:
Wan, Wei-Chao
;
Chen, Wen
;
Liu, Lan-Xiang
;
Li, Yan
;
Yang, Li-Juan
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  |  
浏览/下载:19/0
  |  
提交时间:2014/04/09
Hybrid compound
Benzofuran
Imidazole
Cytotoxic activity
Structure-activity relationships
Molecular docking
Synthesis and cytotoxic activities of novel hybrid 2-phenyl-3-alkylbenzofuran and imidazole/triazole compounds
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 15, 页码: 4297-4302
作者:
Chen, Wen
;
Deng, Xiao-Yan
;
Li, Yan
;
Yang, Li-Juan
;
Wan, Wei-Chao
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2013/10/16
Hybrid Compound
Benzofuran
Imidazole
Triazole
Structure-activity Relationships
Synthesis and antitumor activities of novel dibenzo[b,d]furan-imidazole hybrid compounds
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 66, 页码: 423-437
作者:
Liu, Lan-Xiang
;
Wang, Xue-Quan
;
Yan, Ju-Ming
;
Li, Yan
;
Sun, Cheng-Jun
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  |  
浏览/下载:12/0
  |  
提交时间:2013/10/16
Hybrid Compound
Imidazole
Dibenzo[b
Antitumor Activities
d]Furan
Structure-activity Relationships
Novel Tricyclic Indeno[5,6-b] furan-imidazole Hybrid Compounds: Design, Synthesis and Antitumor Activity
期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2013, 卷号: 10, 期号: 7, 页码: 561-571
作者:
Chen, Wen
;
Yang, Li-Juan
;
Li, Yan
;
Wang, Xue-Quan
;
Wang, Shao-Jie
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  |  
浏览/下载:12/0
  |  
提交时间:2013/10/16
Hybrid Compound
Imidazole
Synthesis
Indeno[5
Cytotoxic Activity
6-b]Furan
Structure-activity Relationships
Discovery and structure-activity relationships of ent-Kaurene diterpenoids as potent and selective 11 beta-HSD1 inhibitors: Potential impact in diabetes
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 65, 页码: 403-414
作者:
Deng, Xu
;
Shen, Yu
;
Yang, Jing
;
He, Juan
;
Zhao, Yu
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  |  
浏览/下载:13/0
  |  
提交时间:2013/10/16
Ent-kaurene Diterpenoids
Structure-activity Relationship Studies
Selective 11 Beta-hsd1 Inhibitors
Urea Derivatives
Diabetes
Design, synthesis and biological evaluation of novel hybrid compounds of imidazole scaffold-based 2-benzylbenzofuran as potent anticancer agents
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 62, 页码: 111-121
作者:
Wang, Xue-Quan
;
Liu, Lan-Xiang
;
Li, Yan
;
Sun, Cheng-Jun
;
Chen, Wen
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2013/07/24
Hybrid compound
2-Benzylbenzofuran
Imidazole
Cytotoxic activities
Structure-activity relationships
Cristatumins A-D, new indole alkaloids from the marine-derived endophytic fungus Eurotium cristatum EN-220
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 14, 页码: 4650-4653
作者:
Du, Feng-Yu
;
Li, Xiao-Ming
;
Li, Chun-Shun
;
Shang, Zhuo
;
Wang, Bin-Gui
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2013/09/24
Marine endophyte
Eurotium cristatum
Indole alkaloid
Antimicrobial activity
Brine shrimp inhibition
The effects of diketopiperazines from Callyspongia sp on release of cytokines and chemokines in cultured J774A.1 macrophages
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 9, 页码: 3177-3180
作者:
Lan, XP
;
jiaaiqun@gmail.com
;
yonghongliu@scsio.ac.cn
;
Jia, AQ
;
Liu, YH
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2013/08/28
Cytokine
Chemokine
Diketopiperazines
J774a.1 Macrophage
Structure-activity Relationships
Anti-HBV agents. Part 3: Preliminary structure-activity relationships of tetra-acylalisol A derivatives as potent hepatitis B virus inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 卷号: 19, 期号: 23, 页码: 6659-6665
作者:
Zhang, Quan
;
Jiang, Zhi-Yong
;
Luo, Jie
;
Ma, Yun-Bao
;
Liu, Ji-Feng
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2012/03/21
Anti-hbv Activity
Protostane-type Triterpene
Alisol a
Derivatives
Chemical Modification
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