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科研机构
上海药物研究所 [8]
金属研究所 [1]
西北高原生物研究所 [1]
合肥物质科学研究院 [1]
内容类型
期刊论文 [11]
发表日期
2021 [11]
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Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an ERK-FBXO22-BAG3 axis in tumorigenesis
期刊论文
CELL DEATH AND DIFFERENTIATION, 2021, 页码: 13
作者:
Liu, Ping
;
Cong, Xiaoji
;
Liao, Shengjie
;
Jia, Xinglong
;
Wang, Xiaomin
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2021/08/17
The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability
期刊论文
MOLECULAR CELL, 2021, 卷号: 81, 期号: 13, 页码: 2736-+
作者:
Pan, Qiang
;
Zhong, Shanshan
;
Wang, Hanling
;
Wang, Xuege
;
Li, Ni
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2021/11/04
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target
期刊论文
CELL RESEARCH, 2021, 页码: 14
作者:
Xia, Bingqing
;
Shen, Xurui
;
He, Yang
;
Pan, Xiaoyan
;
Liu, Feng-Liang
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2021/08/17
Electrochemical and surface analytical studies of transition metal bipyridine dicarboxylic acid complexes as corrosion inhibitors for a mild steel in HCl solution
期刊论文
JOURNAL OF ADHESION SCIENCE AND TECHNOLOGY, 2021, 页码: 17
作者:
Liu, Xia
;
Sun, Yue
;
Lu, Meiheng
;
Pan, Xuemei
;
Wang, Zhengbin
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  |  
浏览/下载:24/0
  |  
提交时间:2021/10/15
Corrosion inhibitor
transition metal complex
adsorption
acid corrosion
The ups, downs and new trends of IDO1 inhibitors
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 12
作者:
Chen, Shulun
;
Tan, Jing
;
Zhang, Ao
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/08/17
Immunotherapy
Cancer
Indoleamine 2,3-dioxygenase
Tryptophan 2,3-dioxygenase
Inhibitors
Checkpoint Inhibitor
Design, synthesis, and biological evaluation of 4-benzoylamino-1H-pyrazole-3-carboxamide derivatives as potent CDK2 inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 12
作者:
Lin, Tingting
;
Li, Jiacheng
;
Liu, Liping
;
Li, Yuanqing
;
Jiang, Hualiang
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2021/05/24
CDK2 inhibitor
Selectivity
Anti-proliferative potency
Discovery of selective HDAC/BRD4 dual inhibitors as epigenetic probes
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 20
作者:
Chen, Jingjing
;
Li, Yalei
;
Zhang, Jie
;
Zhang, Minmin
;
Wei, Aihuan
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/05/24
HDAC
BRD4
Selective dual inhibitors
Anticancer
PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma
期刊论文
THERANOSTICS, 2021, 卷号: 11, 期号: 11, 页码: 5387-5403
作者:
Wang, Jianfeng
;
Wang, Chen
;
Xu, Pan
;
Li, Xiao
;
Lu, Yongning
收藏
  |  
浏览/下载:130/0
  |  
提交时间:2021/05/24
clear cell renal cell carcinoma
protein arginine methyltransferase 1
therapeutic
lipocalin2 (LCN2)
sunitinib
Remarkable Response of Toripalimab Combined with Chemotherapy in Sarcomatoid Carcinoma of Palatine Tonsil: A Case Report
期刊论文
JOURNAL OF MULTIDISCIPLINARY HEALTHCARE, 2021, 卷号: 14
作者:
Huang, Jiahuan
;
Lei, Lei
;
Chen, Bo
;
Pan, Guoqiang
;
Wang, Xiaojiao
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/04/26
chemotherapy
combination therapy
palatine tonsil cancer
PD-1 inhibitor
sarcomatoid carcinoma
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