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科研机构
上海药物研究所 [18]
内容类型
期刊论文 [18]
发表日期
2020 [18]
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浏览/检索结果:
共18条,第1-10条
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发表日期:2020
专题:上海药物研究所
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Immune Checkpoint Blockade in Cancer Immunotherapy: Mechanisms, Clinical Outcomes, and Safety Profiles of PD-1/PD-L1 Inhibitors
期刊论文
ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2020, 卷号: 68, 期号: 6, 页码: 15
作者:
Yan, Yan
;
Zhang, Li
;
Zuo, Yun
;
Qian, Heya
;
Liu, Chang
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/05/24
Immune checkpoints
PD-1
PD-L1
Monoclonal antibody
Immunotherapy
Emerging roles of class I PI3K inhibitors in modulating tumor microenvironment and immunity
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Sun, Pu
;
Meng, Ling-hua
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/12/21
phosphoinositide 3-kinase (PI3K)
PI3K inhibitors
tumor microenvironment
immune cells
immunotherapy
SAF-189s, a potent new-generation ROS1 inhibitor, is active against crizotinib-resistant ROS1 mutant-driven tumors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7
作者:
Xia, Zong-jun
;
Ji, Yin-chun
;
Sun, De-qiao
;
Peng, Xia
;
Gao, Ying-lei
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2020/12/21
ROS1 kinase
ROS1 inhibitor
SAF-189s
lorlatinib
crizotinib resistance
G2032R mutant
NSCLC
Comparative Transcriptomic and Proteomic Analyses Prove that IFN-lambda 1 is a More Potent Inducer of ISGs than IFN-alpha against Porcine Epidemic Diarrhea Virus in Porcine Intestinal Epithelial Cells
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2020, 卷号: 19, 期号: 9, 页码: 3697-3707
作者:
Zhao, Mingzhi
;
Li, Liang
;
Zhai, Linhui
;
Yue, Qi
;
Liu, Hongyu
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2020/12/21
intestinal epithelial cell
IFN-lambda 1
IFN-alpha
anti-PEDV
transcriptomics
proteomics
Sulfation predominates the pharmacokinetics, metabolism, and excretion of forsythin in humans: major enzymes and transporters identified
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Pan, Lu-lu
;
Yang, Yong
;
Hui, Min
;
Wang, Shuo
;
Li, Cui-yun
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2020/12/24
forsythin
pharmacokinetics
drug metabolism
drug excretion
sulfation
glucuronidation
organic anion transporter 3
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Zhang, Xiao-tuan
;
Hu, Xiao-bei
;
Wang, Han-lin
;
Kan, Wei-juan
;
Xu, Lei
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/12/24
DLBCL
BTK inhibitor
ibrutinib resistance
UPR
TUDCA
2-DG
The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-kappa B/NLRP3 signaling
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yang, Fang-ming
;
Fan, Di
;
Yang, Xiao-qian
;
Zhu, Feng-hua
;
Shao, Mei-juan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
dry eye disease
artemisinin derivative
beta-aminoarteether maleate
inflammation
macrophages
TLR4
inflammasome
Cancer nanomedicine meets immunotherapy: opportunities and challenges
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 7, 页码: 954-958
作者:
Sun, Qingxue
;
Bai, Xiangyang
;
Sofias, Alexandros Marios
;
van der Meel, Roy
;
Ruiz-Hernandez, Eduardo
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/12/24
nanomedicine
immunotherapy
targeting
combination therapy
clinical translation
Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Tian, Qian-qian
;
Zhu, Yun-ting
;
Diao, Xing-xing
;
Zhang, Xiang-lei
;
Xu, Ye-chun
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2020/12/24
PDE5 inhibitor
TPN729
M3
species difference
pharmacokinetics
metabolite identification
Update of P2Y receptor pharmacology: IUPHAR Review 27
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 11, 页码: 2413-2433
作者:
Jacobson, Kenneth A.
;
Delicado, Esmerilda G.
;
Gachet, Christian
;
Kennedy, Charles
;
von Kuegelgen, Ivar
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/07/01
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