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浏览/检索结果: 共16条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7 作者:  Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan 收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24 Drug design  CBP  Bromodomain  Inhibitor  Acute myeloid leukemia   Development of Bisindole-Substituted Aminopyrazoles as Novel GSK-3 beta Inhibitors with Suppressive Effects against Microglial Inflammation and Oxidative Neurotoxicity 期刊论文 ACS CHEMICAL NEUROSCIENCE, 2020, 卷号: 11, 期号: 20, 页码: 3398-3408 作者:  Liu, Jian-Guo;  Zhao, Danfeng;  Gong, Qi;  Bao, Fengxia;  Chen, Wen-Wen 收藏  |  浏览/下载：16/0  |  提交时间：2021/05/24 Glycogen synthase kinase-3  bisindole-substituted aminopyrazoles  Alzheimer's disease  oxidative neurotoxicity  microglial inflammation   The homogenous polysaccharide SY01-23 purified from leaf of Morus alba L. has bioactivity on human gut Bacteroides ovatus and Bacteroides cellulosilyticus 期刊论文 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 158, 页码: 698-707 作者:  Wang, Yeqing;  Shao, Saicong;  Guo, Ciliang;  Zhang, Shihai;  Li, Meixia 收藏  |  浏览/下载：14/0  |  提交时间：2020/12/24 Morus alba L.  Polysaccharide  Human gut microbiota  Cross-feeding  Short-chain fatty acids   Pinkment: a synthetic platform for the development of fluorescent probes for diagnostic and theranostic applications 期刊论文 CHEMICAL SCIENCE, 2020, 卷号: 11, 期号: 32, 页码: 8567-8571 作者:  Weber, Maria;  Han, Hai-Hao;  Li, Bo-Han;  Odyniec, Maria L.;  Jarman, Charlotte E. F. 收藏  |  浏览/下载：27/0  |  提交时间：2020/12/24 Asperbutenolide A, an unusual aromatic butenolide dimer with diverse bioactivities from a marine-derived fungus Aspergillus terreus SCAU011 期刊论文 TETRAHEDRON LETTERS, 2020, 卷号: 61, 期号: 32, 页码: 6 作者:  Bao, Jie;  Li, Xiu-Xiu;  He, Fei;  Zhang, Xiaoyong;  Zhu, Kongkai 收藏  |  浏览/下载：15/0  |  提交时间：2020/12/24 Aspergillus terreus  Asperbutenolide A  Butyrolactone  Butenolide   Dihydro-stilbene gigantol relieves CCl4-induced hepatic oxidative stress and inflammation in mice via inhibiting C5b-9 formation in the liver 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 14 作者:  Xue, Ya-ru;  Yao, Sheng;  Liu, Qian;  Peng, Zhao-liang;  Deng, Qiang-qiang 收藏  |  浏览/下载：61/0  |  提交时间：2020/07/01 gigantol  Chinese traditional medicine  liver injury  oxidative stress  inflammation  label-free proteomic  complement and coagulation cascades  terminal complement complex   Alteration of protein homeostasis mediates the interaction of Pseudomonas aeruginosa with Staphylococcus aureus 期刊论文 MOLECULAR MICROBIOLOGY, 2020, 页码: 20 作者:  Yang, Nana;  Cao, Qiao;  Hu, Shuyang;  Xu, Chenchen;  Fan, Ke 收藏  |  浏览/下载：130/0  |  提交时间：2020/07/01 ClpXP  microbial interspecies interactions  proteolysis  Pseudomonas aeruginosa  quorum sensing   Research progress on the protective effects of licorice-derived 18 beta-glycyrrhetinic acid against liver injury 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9 作者:  Wu, Shou-yan;  Wang, Wen-jie;  Dou, Jin-hui;  Gong, Li-kun 收藏  |  浏览/下载：49/0  |  提交时间：2020/07/01 18 beta-glycyrrhetic acid  licorice preparation  liver injury  glycyrrhetinic acid target   A Network-Based Approach to Explore the Mechanisms of Uncaria Alkaloids in Treating Hypertension and Alleviating Alzheimer's Disease 期刊论文 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 5, 页码: 19 作者:  Wu, Wenyong;  Zhang, Zijia;  Li, Feifei;  Deng, Yanping;  Lei, Min 收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01 Uncaria alkaloids  network pharmacology  hypertension  Alzheimer's disease  butyrylcholinesterase  molecular docking   Polysaccharides from Lycium barbarum ameliorate amyloid pathology and cognitive functions in APP/PS1 transgenic mice 期刊论文 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 144, 页码: 1004-1012 作者:  Zhou, Yue;  Duan, Yanhong;  Huang, Shichao;  Zhou, Xuan;  Zhou, Lishuang 收藏  |  浏览/下载：35/0  |  提交时间：2020/07/01 Lycium barbarum polysaccharides  Alzheimer's disease  Amyloid-beta  Synaptic plasticity  Neuropathology