CORC

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CORC

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Characterization of TPN171 metabolism in humans via ultra-performance liquid chromatography/quadrupole time-of-flight Checir for mass spectrometry 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 172, 页码: 302-310
作者:  Pan, Lulu;  Guo, Shuang;  Chen, Xiaoyan;  Jiang, Xiangrui;  Shen, Jingshan
收藏  |  浏览/下载：57/0  |  提交时间：2020/07/01
Inhibition of phosphodiesterase-4 attenuates murine ulcerative colitis through interference with mucosal immunity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2209-2226
作者:  Li, Heng;  Fan, Chen;  Feng, Chunlan;  Wu, Yanwei;  Lu, Huimin
收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01
Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5579-5593
作者:  Zhang, Xianglei;  Dong, Guangyu;  Li, Heng;  Chen, Wuyan;  Li, Jian
收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Zhen;  Jiang, Xiangrui;  Zhang, Xianglei;  Tian, Guanghui;  Yang, Rulei
收藏  |  浏览/下载：40/0  |  提交时间：2020/07/01
Rolipram, a PDE4 Inhibitor, Enhances the Inotropic Effect of Rat Heart by Activating SERCA2a 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 12
作者:  Huang, Huili;  Xie, Ming;  Gao, Li;  Zhang, Wenhui;  Zhu, Xiaojia
收藏  |  浏览/下载：58/0  |  提交时间：2019/06/20
Rolipram, a pde4 inhibitor, enhances the inotropic effect of rat heart by activating serca2a 期刊论文
Frontiers in pharmacology, 2019, 卷号: 10, 页码: 12
作者:  Huang, Huili;  Xie, Ming;  Gao, Li;  Zhang, Wenhui;  Zhu, Xiaojia
收藏  |  浏览/下载：94/0  |  提交时间：2019/05/08
PHOSPHODIESTERASE INHIBITOR TYPE 5 (PDE 5), AND PREPARATION METHOD AND APPLICATION THEREOF 专利
申请日期: 2019-01-03, 公开日期: 2019-01-03
作者:  Lou HX(娄红祥);  Zheng HB(郑泓波);  Sun B(孙斌);  Li L(李琳);  Gao Y(高云)
收藏  |  浏览/下载：4/0  |  提交时间：2020/01/04
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Z (Wang, Zhen)[ 1 ];  Jiang, XR (Jiang, Xiangrui)[ 1 ];  Zhang, XL (Zhang, Xianglei)[ 1,2 ];  Tian, GH (Tian, Guanghui)[ 3 ];  Yang, RL (Yang, Rulei)[ 3 ]
收藏  |  浏览/下载：137/0  |  提交时间：2019/06/28
Phosphodiesterase type 3A (PDE3A), but not type 3B (PDE3B), contributes to the adverse cardiac remodeling induced by pressure overload 期刊论文
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2019, 卷号: 132
作者:  Lakin, Robert;  Ahmad, Faiyaz;  Gao, Xiaodong;  Turnbull, Patrick C.;  Chiarello, Carmelina
收藏  |  浏览/下载：23/0  |  提交时间：2019/12/05
Phosphodiesterase 7B/microRNA-200c relationship regulates triple-negative breast cancer cell growth 期刊论文
Oncogene, 2019, 卷号: 38, 页码: 1106-1120
作者:  Zhang Dan-Dan[1];  Li Yue[2];  Xu Yuan[3];  Kim Jaejik[4];  Huang Shuang[5]
收藏  |  浏览/下载：17/0  |  提交时间：2019/04/22

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