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浏览/检索结果: 共16条，第1-10条 帮助 限定条件 发表日期：2019    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer 期刊论文 CELL METABOLISM, 2019, 卷号: 30, 期号: 6, 页码: 1107-+ 作者:  Huang, Ke;  Liang, Qian;  Zhou, Ye;  Jiang, Lu-lu;  Gu, Wei-ming 收藏  |  浏览/下载：77/0  |  提交时间：2020/07/01 AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition 期刊论文 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1587-1595 作者:  Zhang, Kai-li;  Shen, Qian-qian;  Fang, Yan-fen;  Sun, Yi-ming;  Ding, Jian 收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01 PRC2  EZH2-EED  AZD9291  miR-34a  non-canonical base pairing   Simultaneous determination of alflutinib and its active metabolite in human plasma using liquid chromatography-tandem mass spectrometry 期刊论文 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 176, 页码: 6 作者:  Liu, Xiaoyun;  Li, Wei;  Zhang, Yifan;  Jian, Yong;  Zhao, Qianyu 收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01 LC-MS/MS  Alflutinib  AST2818  Pharmacokinetics  Human plasma   Activation and function of receptor tyrosine kinases in human clear cell renal cell carcinomas 期刊论文 BMC CANCER, 2019, 卷号: 19, 期号: 1, 页码: 13 作者:  Zhang, Qing;  Liu, Jian-He;  Liu, Jing-Li;  Qi, Chun-Ting;  Yan, Lei 收藏  |  浏览/下载：61/0  |  提交时间：2020/07/01 Receptor tyrosine kinases (RTKs)  Activation and function  Clear cell renal cell carcinomas (ccRCCs)  Targeted therapy  PDGFR beta  Stroma cells   SHR-A1403, a novel c-mesenchymal-epithelial transition factor (c-Met) antibody-drug conjugate, overcomes AZD9291 resistance in non-small cell lung cancer cells overexpressing c-Met 期刊论文 CANCER SCIENCE, 2019, 页码: 11 作者:  Tong, Mengya;  Gao, Mingzhao;  Xu, Yongping;  Fu, Li;  Li, Yun 收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01 AZD9291  c-Met ADC  c-Met overexpression  resistance  SHR-A1403   Structure-Based Design of 5-Methylpyrimidopyridone Derivatives as New Wild-Type Sparing Inhibitors of the Epidermal Growth Factor Receptor Triple Mutant (EGFR(L858R/T790M/C797S)) 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 15, 页码: 7302-7308 作者:  Shen, Jiayi;  Zhang, Tao;  Zhu, Su-Jie;  Sun, Min;  Tong, Linjiang 收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01 Discovery and Biological evaluation of pyrimido[4,5-d] pyrimidine-2,4(1H, 3H)-dione derivatives as potent Bruton's tyrosine kinase inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3390-3395 作者:  Diao, Yanyan;  Fang, Xiaoyu;  Song, Peiran;  Lai, Mengzhen;  Tong, Linjiang 收藏  |  浏览/下载：23/0  |  提交时间：2020/07/01 Bruton's tyrosine kinase  B-cell malignancies  Potent inhibitors  Structure-activity relationship  Cellular activities   UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis 期刊论文 NATURE, 2019, 卷号: 571, 期号: 7763, 页码: 127-+ 作者:  Wang, Xiongjun;  Liu, Ruilong;  Zhu, Wencheng;  Chu, Huiying;  Yu, Hua 收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01 Discovery of a novel third generation EGFR TKI and identification of its potential mechanism of resistance 期刊论文 CANCER RESEARCH, 2019, 卷号: 79, 期号: 13, 页码: 2 作者:  Zhang, Tao;  Qu, Rong;  Chen, Chengbin;  Tong, Linjiang;  Feng, Fang 收藏  |  浏览/下载：4/0  |  提交时间：2020/07/01 Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer 期刊论文 NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 15 作者:  Jin, Nan;  Bi, Aiwei;  Lan, Xiaojing;  Xu, Jun;  Wang, Xiaomin 收藏  |  浏览/下载：61/0  |  提交时间：2020/07/01