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西北高原生物研究所 [9]
上海药物研究所 [8]
深圳先进技术研究院 [3]
山东大学 [3]
中国医学科学院 北京... [3]
水生生物研究所 [2]
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期刊论文 [47]
会议论文 [1]
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2018 [48]
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Biology [1]
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Design and optimization of 2,3-dihydrobenzo[b][1,4]dioxine propanoic acids as novel GPR40 agonists with improved pharmacokinetic and safety profiles
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 22, 页码: 5780-5791
作者:
Guo, Bin
;
Guo, Shimeng
;
Huang, Jing
;
Li, Jingya
;
Li, Jia
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
GPR40 agonist
2,3-Dihydrobenzo[b][1,4]dioxine
Insulin secretion
Type 2 diabetes mellitus
ETA as a novel Kv2.1 inhibitor ameliorates beta-cell dysfunction and hyperglycaemia
期刊论文
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2018, 卷号: 45, 期号: 12, 页码: 1257-1264
作者:
Zhou, Tingting
;
Du, Mengfan
;
Zhao, Tong
;
Quan, Lingling
;
Zhu, Zhiyuan
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  |  
浏览/下载:94/0
  |  
提交时间:2019/01/08
beta cell
apoptosis
glucose-stimulated insulin secretion
T2DM
Effects of glucose on biochemical immune responses and hepatic gene expression in common carp, Cyprinus carpio L
期刊论文
BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT, 2018, 卷号: 32, 期号: 6, 页码: 1440-1446
作者:
Yu, Fan
;
Li, Jianlin
;
Li, Hongxia
;
Tang, Yongkai
;
Wang, Meiyao
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  |  
浏览/下载:42/0
  |  
提交时间:2019/06/11
Common carp
glucose
serum
transcriptome
immune response
Plasma bile acid changes in type 2 diabetes correlated with insulin secretion in two-step hyperglycemic clamp
期刊论文
JOURNAL OF DIABETES, 2018, 卷号: 10, 期号: 11, 页码: 874-885
作者:
Xie, Xiaoyan
;
Ma, Jing
;
Xu, Min
;
Zhao, Xinjie
;
Gu, Weiqiong
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2019/06/20
bile acid
hyperglycemic clamp
insulin secretion
type 2 diabetes mellitus
Anti-diabetic Effect of Punica granatum Flower Polyphenols Extract in Type 2 Diabetic Rats: Activation of Akt/GSK-3 beta and Inhibition of IRE1 alpha-XBP1 Pathways
期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2018, 卷号: 9
作者:
Tang, Dan
;
Liu, Liu
;
Ajiakber, Dildar
;
Ye, Jianping
;
Xu, Jianjun
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  |  
浏览/下载:69/0
  |  
提交时间:2019/01/08
type 2 diabetes mellitus
Punica granatum L. flower
anti-diabetic herb
oral glucose tolerance test
endoplasmic reticulum stress
insulin resistance
Effects of glucose administration on glucose and lipid metabolism in two strains of gibel carp (Carassius gibelio)
期刊论文
GENERAL AND COMPARATIVE ENDOCRINOLOGY, 2018, 卷号: 267, 期号: 1, 页码: 18-28
作者:
Jin, Junyan
;
Yang, Yunxia
;
Zhu, Xiaoming
;
Han, Dong
;
Liu, Haokun
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/07/02
Glucose injection
Liver
Muscle
Genotype
A strain
DT strain
Effects of glucose administration on glucose and lipid metabolism in two strains of gibel carp (Carassius gibelio)
期刊论文
GENERAL AND COMPARATIVE ENDOCRINOLOGY, 2018, 卷号: 267, 页码: 18-28
作者:
Xie, Shouqi
;
Liu, Haokun
;
Han, Dong
;
Zhu, Xiaoming
;
Yang, Yunxia
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  |  
浏览/下载:29/0
  |  
提交时间:2018/12/29
Glucose injection
Liver
Muscle
Genotype
A strain
DT strain
Cys(2)His(2) Zinc Finger Transcription Factor BcabaR1 Positively Regulates Abscisic Acid Production in Botrytis cinerea
期刊论文
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2018, 卷号: 84, 期号: 17, 页码: UNSP e00920-18
作者:
Wang, Yingming
;
Zhou, Jinyan
;
Zhong, Juan
;
Luo, Di
;
Li, Zhemin
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/12/24
abscisic acid
transcription factor
promoter
Botrytis cinerea
Discovery of novel selective GPR120 agonists with potent anti-diabetic activity by hybrid design
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 15, 页码: 2599-2604
作者:
Sheng, Ren
;
Yang, Liu
;
Zhang, Yanchun
;
Xing, Enming
;
Shi, Rui
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
GPR120
Agonist biphenyl derivatives
OGTT
Type 2 diabetes
A high-performance chiral selector derived from chitosan (p-methylbenzylurea) for efficient enantiomer separation
期刊论文
TALANTA, 2018, 卷号: 185, 页码: 42-52
作者:
Tang, Sheng
;
Mei, Xiaomeng
;
Chen, Wei
;
Huang, Shao-Hua
;
Bai, Zheng-Wu
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  |  
浏览/下载:56/0
  |  
提交时间:2018/12/21
Chitin
Chitosan
Polysaccharide
Chiral Stationary Phase
Enantiomer Separation
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