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CORC

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DNA methylation and expression profiles of placenta and umbilical cord blood reveal the characteristics of gestational diabetes mellitus patients and offspring 期刊论文
Clinical Epigenetics, 2022, 卷号: 14
作者:  Lu,Sha;  Wang,Jiahao;  Kakongoma,Nisile;  Hua,Wen;  Xu,Jiahui
收藏  |  浏览/下载：12/0  |  提交时间：2022/12/22
Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Li, Teng-teng;  Peng, Cheng;  Wang, Ji-qiu;  Xu, Zhi-jian;  Su, Ming-bo
收藏  |  浏览/下载：39/0  |  提交时间：2022/01/18
Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site 期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 11, 页码: 2444-2452
作者:  Wang, Jiang;  Yang, Dehua;  Cheng, Xi;  Yang, Linlin;  Wang, Zhaohui
收藏  |  浏览/下载：23/0  |  提交时间：2022/01/04
Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14
作者:  He, Yu-Long;  Chen, Meng-Ting;  Wang, Ting;  Zhang, Ming-Ming;  Li, Ying-Xia
收藏  |  浏览/下载：61/0  |  提交时间：2021/11/04
Identification of Betulinic Acid Derivatives as Potent TGR5 Agonists with Antidiabetic Effects via Humanized TGR5(H88Y) Mutant Mice 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12181-12199
作者:  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Liang, Xiaoying;  Lan, Yuan
收藏  |  浏览/下载：40/0  |  提交时间：2021/11/04
Intestinal MYC modulates obesity-related metabolic dysfunction 期刊论文
NATURE METABOLISM, 2021, 页码: 37
作者:  Luo, Yuhong;  Yang, Shoumei;  Wu, Xuan;  Takahashi, Shogo;  Sun, Lulu
收藏  |  浏览/下载：27/0  |  提交时间：2021/08/17
A novel GPR120-selective agonist promotes insulin secretion and improves chronic inflammation 期刊论文
LIFE SCIENCES, 2021, 卷号: 269, 页码: 8
作者:  Yang, Liu;  Lei, Xian-Tao;  Huang, Qi;  Wang, Ting;  Sun, Hong-Bin
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24
Insights into the molecular mechanism of positive cooperativity between partial agonist MK-8666 and full allosteric agonist AP8 of hGPR40 by Gaussian accelerated molecular dynamics (GaMD) simulations 期刊论文
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2021, 卷号: 19, 页码: 3978-3989
作者:  An, Xiaoli;  Bai, Qifeng;  Bing, Zhitong;  Liu, Huanxiang;  Yao, Xiaojun
收藏  |  浏览/下载：12/0  |  提交时间：2021/12/08
The phosphatidylserine flippase beta-subunit Tmem30a is essential for normal insulin maturation and secretion 期刊论文
MOLECULAR THERAPY, 2021, 卷号: 29, 期号: 9
作者:  Yang, Yeming;  Sun, Kuanxiang;  Liu, Wenjing;  Li, Xiao;  Tian, Wanli
收藏  |  浏览/下载：26/0  |  提交时间：2021/11/18
DGAT1 inhibitors protect pancreatic beta-cells from palmitic acid-induced apoptosis 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:  Huang, Jun-shang;  Guo, Bin-bin;  Wang, Gai-hong;  Zeng, Li-min;  Hu, You-hong
收藏  |  浏览/下载：53/0  |  提交时间：2020/12/24

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