QQ客服 官方微博 反馈留言

浏览/检索结果: 共20条，第1-10条 帮助 限定条件 发表日期：2018    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 The secretome engages STAT3 to favor a cytokine-rich microenvironment in mediating acquired resistance to FGFR inhibitors 期刊论文 Molecular cancer therapeutics, 2018, 卷号: 145, 页码: 817-842 作者:  Wang, Xinyi;  Ai, Jing;  Liu, Hongyan;  Peng, Xia;  Chen, Hui 收藏  |  浏览/下载：135/0  |  提交时间：2019/01/08 1,4-Diaryl-2-azetidinone  Combretastatin A-4  Tubulin polymerization  Antitumor   Remodeling Tumor-Associated Macrophages and Neovascularization Overcomes EGFR(T790M)-Associated Drug Resistance by PD-L1 Nanobody-Mediated Codelivery 期刊论文 SMALL, 2018, 卷号: 14, 期号: 47 作者:  Yin, Weimin;  Yu, Xiaolu;  Kang, Xuejia;  Zhao, Yuge;  Zhao, Pengfei 收藏  |  浏览/下载：100/0  |  提交时间：2019/01/08 antiangiogenesis  EGFR(T790M) mutation  PD-L1 nanobody  simvastatin  tumor-associated macrophage   Novel substituted pyrazolone derivatives as AMP-activated protein kinase activators to inhibit lipid synthesis and reduce lipid accumulation in ob/ob mice 期刊论文 ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 10, 页码: 1622-1632 作者:  Zhang, Mei;  Xie, Zhi-fu;  Zhang, Run-tao;  Chen, Da-kai;  Gu, Min 收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08 non-alcoholic fatty liver disease  AMP-activated protein kinase  AMPK activator  homogeneous time-resolved fluorescence  metabolic disorders  ob/ob mice   A preclinical overview of metformin for the treatment of type 2 diabetes 期刊论文 BIOMEDICINE & PHARMACOTHERAPY, 2018, 卷号: 106, 页码: 1227-1235 作者:  Zhou, Tingting;  Xu, Xin;  Du, Mengfan;  Zhao, Tong;  Wang, Jiaying 收藏  |  浏览/下载：45/0  |  提交时间：2019/01/08 Gluconeogenesis  Insulin sensitivity  Mechanism  Metformin  Type 2 diabetes (T2D)   STAT3 activation confers trastuzumab-emtansine (T-DM1) resistance in HER2-positive breast cancer 期刊论文 CANCER SCIENCE, 2018, 卷号: 109, 期号: 10, 页码: 3305-3315 作者:  Wang, Lei;  Wang, Quanren;  Gao, Mingzhao;  Fu, Li;  Li, Yun 收藏  |  浏览/下载：50/0  |  提交时间：2019/01/08 drug resistance  leukemia inhibitory factor receptor  secreted factor  STAT3  trastuzumab-emtansine   Arsenic circumvents the gefitinib resistance by binding to P62 and mediating autophagic degradation of EGFR in non-small cell lung cancer 期刊论文 CELL DEATH & DISEASE, 2018, 卷号: 9 作者:  Mao, Jianhua;  Ma, Lie;  Shen, Yan;  Zhu, Kongkai;  Zhang, Ru 收藏  |  浏览/下载：49/0  |  提交时间：2019/01/08 Glycyrrhizin has a high likelihood to be a victim of drug-drug interactions mediated by hepatic organic anion-transporting polypeptide 1B1/1B3 期刊论文 BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 17, 页码: 3486-3503 作者:  Dong, Jiajia;  Olaleye, Olajide E.;  Jiang, Rongrong;  Li, Jing;  Lu, Chuang 收藏  |  浏览/下载：98/0  |  提交时间：2019/01/08 The mTOR inhibitor AZD8055 overcomes tamoxifen resistance in breast cancer cells by down-regulating HSPB8 期刊论文 ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 8, 页码: 1338-1346 作者:  Shi, Jia-jie;  Chen, Si-meng;  Guo, Chen-Liang;  Li, Yi-xue;  Ding, Jian 收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 tamoxifen resistance  HSPB8  AZD8055  estrogen receptor  mTOR inhibitor   SILAC-based quantitative proteomic analysis of the livers of spontaneous obese and diabetic rhesus monkeys 期刊论文 AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2018, 卷号: 315, 期号: 2, 页码: E294-E306 作者:  Wang, Junlong;  Xu, Shimeng;  Gao, Jing;  Zhang, Linqiang;  Zhang, Zhiguo 收藏  |  浏览/下载：103/0  |  提交时间：2019/01/08 liver  rhesus monkey  stable isotope labeling with amino acids in cell culture-based quantitative proteomics  spontaneous Type 2 diabetes   Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy 期刊论文 ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 4, 页码: 552-562 作者:  Liu, Feifei;  Yang, Xiaotong;  Geng, Meiyu;  Huang, Min 收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 Mitogen-activated protein kinases  Extracellular signal-regulated kinase  ERK inhibitor  ERK kinase  Cancer therapy  Drug resistance