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北京大学 [2]
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期刊论文 [9]
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IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation
期刊论文
2019, 卷号: 212, 页码: 36-53
作者:
Ai Q D
;
Chen Chen
;
Chu Shifeng
;
Zhang Zhao
;
Luo Yun
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/01/03
ASC = apoptosis-associated speck-like protein containing a caspase activation recruitment domain
BCA = bicinchoninic acid
BSA = bovine serum albumin
CCA = common carotid artery
CCR4 = C-C chemokine receptor type 4
CKLF1 = chemokine-like factor 1
CO-IP = coimmunoprecipitation
ECA = external carotid artery
ELISA = enzyme-linked immunosorbent assay
FDA = Food and Drug Administration
I/R = ischemic/reperfusion
ICA = internal carotid artery
IL-18 = interleukin 18
IL-1β = interleukin 1β
LDH = lactate dehydrogenase
NLRP3 = NOD-like receptor protein 3
PBS = phosphate-buffered saline
SD = standard deviation
TNF-α = tumor necrosis factor α
TTC = 2
3
5-triphenyltetrazolium-chloride
WT = wild-type
pMCAO = permanent middle cerebral artery occlusion
pro-Caspase-1 = precursor Caspase-1
qPCR = quantitative real-time PCR
tMCAO = transient middle cerebral artery occlusion
tPA = tissue plasminogen activator
Effect of galectin-3 on vasculogenic mimicry in esophageal cancer cells
期刊论文
ONCOLOGY LETTERS, 2018, 卷号: 15, 期号: 4, 页码: 4907-4911
作者:
Zhang, Jingxin
;
Deng, Guodong
;
Qiao, Lili
;
Luo, Hui
;
Liu, Qiqi
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
esophageal cancer cells
galectin-3
vasculogenic mimicry
ephrin type-A
receptor 2 precursor
matrix metalloproteinase 2
Myelin injury in the central nervous system and Alzheimer's disease
期刊论文
Brain Research Bulletin, 2018, 卷号: 140, 页码: 162-168
作者:
Wang, Sha-Sha
;
Zhang, Zhao
;
Zhu, Tian-Bi
;
Chu, Shi-Feng
;
He, Wen-Bin
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/27
OLG
oligodendrocyte
CNS
central nervous system
SC
Schwann cell
PNS
peripheral nervous system
MBP
myelin basic protein
PLP
proteolipid protein
P0/MPZ
myelin protein zero
EAE
experimental allergic encephalomyelitis
MS
multiple sclerosis
CNP
2′ 3′-cyclic nucleotide 3′-phosphodiesterase
MAG
myelin associated glycoprotein
MOG
myelin oligodendrocyte glycoprotein
AD
Alzheimer's disease
OPC
oligodendrocyte precursor cell
NPC
neural progenitor cell
ROS
reactive oxygen species
TNF
tumour necrosis factor
AIF
apoptosis-inducing factor
IFN-γ
interferon gamma
ERK1/2
extracellular signal-regulated kinases-1 and -2
MAPK
mediators of mitogen-activated protein kinase
FGFR1/2
fibroblast growth factor receptors-1 and -2
Dock3
dedicator of cytokinesis 3
PERK
pancreatic endoplasmic reticulum kinase
GEF
guanine nucleotide exchange factor
SIRT2
sirtuin 2
NOD2
Nucleotide-binding oligomerization domain containing protein 2
RIPK2
receptor-interacting serine/threonine kinase 2
Shh
Sonic Hedgehog
NMO
neuromyelitis optica
ADEM
acute disseminated encephalomyelitis
ANHLE
acute necrotizing hemorrhagic leukoencephalitis
CPM
central pontine myelinolysis
Aβ
beta-amyloid
SP
senile plaque
NFT
neurofibrillary tangle
MRI
magnetic resonance imaging
Myelin
Oligodendrocyte
Demyelination
Neurodegenerative diseases
Alzheimer’s disease
Expression of NG2 and platelet-derived growth factor receptor alpha in the developing neonatal rat brain.
期刊论文
Neural regeneration research, 2017, 卷号: 12, 期号: 11
作者:
;
Li Heng-Xi
;
;
Wu Hai-Ying
;
Zhu Lie
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/04
NG2
OX-42
Amoeboid microglial cells
Cerebral cortex
Corpus callosum
Hypoxia
Nerve regeneration
Neural regeneration
Oligodendrocyte precursor cells
Platelet-derived growth factor receptor alpha
Expression of NG2 and platelet-derived growth factor receptor alpha in the developing neonatal rat brain
期刊论文
NEURAL REGENERATION RESEARCH, 2017, 卷号: 12, 页码: 1843-1852
作者:
Li, Ping
;
Li, Heng-xi
;
Jiang, Hong-yan
;
Zhu, Lie
;
Wu, Hai-ying
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/11/26
platelet-derived growth factor receptor alpha
amoeboid microglial cells
corpus callosum
oligodendrocyte precursor cells
neural regeneration
OX-42
hypoxia
NG2
cerebral cortex
nerve regeneration
Bridges between mitochondrial oxidative stress, ER stress and mTOR signaling in pancreatic β cells
期刊论文
Cellular Signalling, 2016, 卷号: 28, 期号: 8, 页码: 1099-1104
作者:
Wang, Jing
;
Yang, Xin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/03
4E-BP1
4E binding protein
AMPK
AMP-activated protein kinase
ATF6
activating transcription factor 6
ATP
adenosine triphosphate
DEPTOR
DEP domain containing mTOR-interacting protein
CI
complexes I
CII
complex II
CIII
complex III
CIV
complex IV
CV
complex V
eIF2α
Eukaryotic Initiation Factor 2α
ER
Endoplasmic Reticulum
ERAD
ER-associated degradation
ERO1α
ER oxidoreductase 1 α
FoxO1
Forkhead box O1
GβL
G Protein β Subunit Like Protein
GRP78
78 kDa glucose-regulated protein precursor
GSIS
glucose-stimulated insulin secretion
IRE1
Inositol-requiring enzyme 1
IRS1
Insulin receptor substrate 1
IRS2
Insulin receptor substrate 2
mLST8
mammalian lethal with sec-13 protein 8
mSin1
the mammalian stress-activated MAP kinase-interaction protein 1
mtDNA
mitochondrial deoxyribonucleic acid
mTOR
mammalian TOR
mTORC1
mTOR complex 1
mTORC2
mTOR complex 2
NADPH oxidase
Nicotinamide adenine dinucleotide phosphate-oxidase
NOS
nitric oxide synthase
O2–·
superoxide anion
H2O2
hydrogen peroxide
OH·
hydroxyl radical
3O2
triplet-state molecular oxygen
OXPHOS
oxidative phosphorylation
CAT
catalase
GPx
glutathioneperoxidase
PERK
Protein kinase R-like endoplasmic reticulum kinase
PDI
ER protein disulfide isomerases
PI3K
the phosphoinositide3-kinase
PRAS40
40-kDa proline-rich Akt substrate
PRAS40
the 40-kDa proline-rich Akt substrate
PROTOR
the protein observed with RICTOR
RAPTOR
regulatory-associated protein of mTOR
RICTOR
The rapamycin-insensitive companion of mTOR
REDD1
DNA damage response 1
RNS
reactive nitrogen species
ROS
reactive oxygen species
RNS
reactive nitrogen species
S6K
S6 kinase
SOD
superoxidedismutase
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TOR
the target of rapamycin
TSC2
Tuberous sclerosis 2
UPR
unfolded protein response
Mitochondrial oxidative stress
ER stress
mTOR
Pancreatic β cells
Primate-specific miR-603 is implicated in the risk and pathogenesis of Alzheimer's disease
期刊论文
AGING-US, 2016
Zhang, Chi
;
Lu, Jie
;
Liu, Bing
;
Cui, Qinghua
;
Wang, Yun
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/12/03
miR-603
single nucleotide polymorphism (SNP)
Alzheimer&apos
pathogenesis
biogenesis
RECEPTOR-RELATED PROTEIN
AMYLOID PRECURSOR PROTEIN
ALPHA-2-MACROGLOBULIN RECEPTOR
TAU-PHOSPHORYLATION
39-KDA PROTEIN
EXPRESSION
BRAIN
CLEARANCE
CELL
SUSCEPTIBILITY
s disease risk
Galanin Protects Amyloid-beta-Induced Neurotoxicity on Primary Cultured Hippocampal Neurons of Rats
期刊论文
journal of alzheimers disease, 2010
Cheng, Yong
;
Yu, Long-Chuan
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/11/14
Amyloid-beta
Bax
Bcl-2
caspase-3
Gal2-11
galanin
galanin receptor 2
hippocampal neuron
MAP2
Morris water maze
neuroprotective effect
p53
ALZHEIMERS-DISEASE
A-BETA
TAUROURSODEOXYCHOLIC ACID
P53-MEDIATED APOPTOSIS
PRECURSOR PROTEIN
BAX TRANSLOCATION
NUCLEUS BASALIS
NERVOUS-SYSTEM
CELL-DEATH
PEPTIDE
Receptor-associated Protein Interacts with Amyloid-beta Peptide and Promotes Its Cellular Uptake
期刊论文
http://dx.doi.org/10.1074/jbc.M109.015032, 2009
Kanekiyo, Takahisa
;
Bu, Guojun
;
卜国军
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/07/22
PRECURSOR PROTEIN
HEPARAN-SULFATE
LDL-RECEPTOR
ALZHEIMERS-DISEASE
APOLIPOPROTEIN-E
ALPHA-2-MACROGLOBULIN RECEPTOR
LIPOPROTEIN RECEPTORS
MOLECULAR CHAPERONE
TRANSGENIC MICE
TERMINAL DOMAIN
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