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南华大学 [6]
中南大学 [5]
湖南中医药大学 [5]
西安交通大学 [3]
山东大学 [3]
武汉大学 [2]
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期刊论文 [31]
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2019 [1]
2018 [8]
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Rutaecarpine may improve neuronal injury, inhibits apoptosis, inflammation and oxidative stress by regulating the expression of ERK 1/2 and Nrf2/HO-1 pathway in rats with cerebral ischemia-reperfusion injury
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2019, 卷号: 13
作者:
Han, Meiyu
;
Hu, Lin
;
Chen, Yang
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/05
cerebral ischemia-reperfusion
rutaecarpine
nuclear factor-erythroid 2 related factor 2
extracellular regulated protein kinases
Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 4, 页码: 552-562
作者:
Liu, Feifei
;
Yang, Xiaotong
;
Geng, Meiyu
;
Huang, Min
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Mitogen-activated protein kinases
Extracellular signal-regulated kinase
ERK inhibitor
ERK kinase
Cancer therapy
Drug resistance
Targeting cysteine-rich angiogenic inducer-61 by antibody immunotherapy suppresses growth and migration of non-small cell lung cancer
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2018, 卷号: 16, 期号: 2, 页码: 730-738
作者:
Li, Xinpeng
;
Yuan, Naxin
;
Lin, Lingdan
;
Yin, Lixia
;
Qu, Yiqing
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
cysteine-rich angiogenic inducer-61
anti-cysteine-rich angiogenic
inducer-61
apoptosis
migration
extracellular signal-regulated
kinases
protein kinase B
non-small cell lung cancer
Amyloid precursor protein is overexpressed in bladder cancer and contributes to the malignant bladder cancer cell behaviors
期刊论文
INTERNATIONAL JOURNAL OF UROLOGY, 2018, 卷号: 25, 期号: 9, 页码: 808-816
作者:
Zhang, Dongqing
;
Zhou, Changkuo
;
Li, Yan
;
Gao, Lijian
;
Pang, Zhipeng
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
amyloid precursor protein
bladder cancer
cell cycle
cell
proliferation
extracellular signal-regulated protein kinases pathway
lncRNAPCAT29 inhibits pulmonary fibrosis via the TGF-1-regulated RASAL1/ERK1/2 signal pathway
期刊论文
MOLECULAR MEDICINE REPORTS, 2018, 卷号: 17, 期号: 6, 页码: 7781-7788
作者:
Liu, Xiaoming
;
Gao, Shanyu
;
Xu, Huile
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/11
pulmonary fibrosis
long non-coding RNA prostate cancer-associated
transcript 29
inflammation
transforming growth factor-1
microRNA-221
RAS protein activator like 1
extracellular signal-regulated kinases 1/2
Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways
期刊论文
Molecular Immunology, 2018, 卷号: 99, 页码: 115-123
作者:
Shao, Qian-hang
;
Zhang, Xiao-ling
;
Chen, Ying
;
Zhu, Cheng-Gen
;
Shi, Jian-Gong
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/27
Akt
protein kinase B
Atg
autophagy related gene
CNS
central nervous system
COX-2
cyclooxygenase-2
CQ
chloroquine
ERK
extracellular signal-regulated kinase
IL-1β
interleukin-1β
iNOS
inducible nitric oxide synthase
JNK
c-jun NH2-terminal kinase
LPS
Lipopolysaccharide
MAPKs
mitogen-activated protein kinases
mTOR
mechanistic target of rapamycin
NO
nitric oxide
PI3K
phosphatidylinositol 3-kinase
PRR
pattern recognition receptor
TLR4
toll like receptor 4
TNF-α
tumor necrosis factor-α
20C
Autophagy
Mitogen-activated protein kinases (MAPKs)
Toll like receptor 4 (TLR4)
Protein kinase B (Akt)
Mechanistic target of rapamycin (mTOR)
Myelin injury in the central nervous system and Alzheimer's disease
期刊论文
Brain Research Bulletin, 2018, 卷号: 140, 页码: 162-168
作者:
Wang, Sha-Sha
;
Zhang, Zhao
;
Zhu, Tian-Bi
;
Chu, Shi-Feng
;
He, Wen-Bin
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/27
OLG
oligodendrocyte
CNS
central nervous system
SC
Schwann cell
PNS
peripheral nervous system
MBP
myelin basic protein
PLP
proteolipid protein
P0/MPZ
myelin protein zero
EAE
experimental allergic encephalomyelitis
MS
multiple sclerosis
CNP
2′ 3′-cyclic nucleotide 3′-phosphodiesterase
MAG
myelin associated glycoprotein
MOG
myelin oligodendrocyte glycoprotein
AD
Alzheimer's disease
OPC
oligodendrocyte precursor cell
NPC
neural progenitor cell
ROS
reactive oxygen species
TNF
tumour necrosis factor
AIF
apoptosis-inducing factor
IFN-γ
interferon gamma
ERK1/2
extracellular signal-regulated kinases-1 and -2
MAPK
mediators of mitogen-activated protein kinase
FGFR1/2
fibroblast growth factor receptors-1 and -2
Dock3
dedicator of cytokinesis 3
PERK
pancreatic endoplasmic reticulum kinase
GEF
guanine nucleotide exchange factor
SIRT2
sirtuin 2
NOD2
Nucleotide-binding oligomerization domain containing protein 2
RIPK2
receptor-interacting serine/threonine kinase 2
Shh
Sonic Hedgehog
NMO
neuromyelitis optica
ADEM
acute disseminated encephalomyelitis
ANHLE
acute necrotizing hemorrhagic leukoencephalitis
CPM
central pontine myelinolysis
Aβ
beta-amyloid
SP
senile plaque
NFT
neurofibrillary tangle
MRI
magnetic resonance imaging
Myelin
Oligodendrocyte
Demyelination
Neurodegenerative diseases
Alzheimer’s disease
Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways
期刊论文
Molecular immunology, 2018, 卷号: 99, 页码: 115-123
作者:
Shao, Qian-hang
;
Zhang, Xiao-ling
;
Chen, Ying
;
Zhu, Cheng-Gen
;
Shi, Jian-Gong
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/27
Akt
protein kinase B
Atg
autophagy related gene
CNS
central nervous system
COX-2
cyclooxygenase-2
CQ
chloroquine
ERK
extracellular signal-regulated kinase
IL-1β
interleukin-1β
iNOS
inducible nitric oxide synthase
JNK
c-jun NH2-terminal kinase
LPS
Lipopolysaccharide
MAPKs
mitogen-activated protein kinases
mTOR
mechanistic target of rapamycin
NO
nitric oxide
PI3K
phosphatidylinositol 3-kinase
PRR
pattern recognition receptor
TLR4
toll like receptor 4
TNF-α
tumor necrosis factor-α
20C
Autophagy
Mitogen-activated protein kinases (MAPKs)
Toll like receptor 4 (TLR4)
Protein kinase B (Akt)
Mechanistic target of rapamycin (mTOR)
Involvement of CGRP-RCP in the caveolin-1/ERK1/2 signal pathway in the static pressure-induced proliferation of vascular smooth muscle cells
期刊论文
Journal of Cellular Physiology, 2018, 卷号: 233, 期号: 10, 页码: 6910-6920
作者:
Guo, Feng
;
Yang, Li
;
Luo, Jingfei
;
Quan, Haiyan
;
Wang, Zhen
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/27
extracellular signal-regulated kinases-1/2
receptor component protein
signal transduction
static pressure
vascular smooth muscle cell
Effects of preweaning environmental enrichment on hippocampus-dependent learning and memory in developing rats
期刊论文
NEUROSCIENCE LETTERS, 2017, 卷号: 640
作者:
Lu, Cheng-Qiu
;
Zhong, Le
;
Yan, Chong-Huai
;
Tian, Ying
;
Shen, Xiao-Ming
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
Enriched environment
Preweaning
Learning and memory
Extracellular signal-regulated kinases
Activity-regulated cytoskeleton-associated protein
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