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浏览/检索结果: 共9条，第1-9条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery, Structure-Activity Relationship, and Mechanistic Studies of 1-((3R,4S)-3-((Dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)-2-(2,4,5-trifluorophenyl)ethan-1-one as a Novel Potent Analgesic 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9458-9483 作者:  Huang, Huoming;  Li, Xueping;  Xie, Peng;  Li, Xinwei;  Xu, XueJun 收藏  |  浏览/下载：28/0  |  提交时间：2021/08/17 Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070 作者:  Xiao, Li;  Wang, Yujun;  Zhang, Mumei;  Wu, Weiwei;  Kong, Linghui 收藏  |  浏览/下载：92/0  |  提交时间：2020/07/01 SNX10 (sorting nexin 10) inhibits colorectal cancer initiation and progression by controlling autophagic degradation of SRC 期刊论文 AUTOPHAGY, 2019, 页码: 15 作者:  Zhang, Sulin;  Yang, Zhiwen;  Bao, Weilian;  Liu, Lixin;  You, Yan 收藏  |  浏览/下载：72/0  |  提交时间：2020/07/01 Colorectal cancer  macroautophagy  SNX10  SRC  tumor growth   Molecular Mechanism of Action of RORt Agonists and Inverse Agonists: Insights from Molecular Dynamics Simulation 期刊论文 MOLECULES, 2018, 卷号: 23, 期号: 12 作者:  Sun, Nannan;  Yuan, Congmin;  Ma, Xiaojun;  Wang, Yonghui;  Gu, Xianfeng 收藏  |  浏览/下载：8/0  |  提交时间：2019/12/05 RORt  molecular mechanism of action (MOA)  agonist  inverse agonist   Computational investigation on the binding modes of Rimonabant analogs with CB1 and CB2 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2018, 卷号: 92, 期号: 3 作者:  Liu, Cheng;  Yuan, Congmin;  Wu, Pinwen;  Zhu, Chen;  Fang, Hao 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/05 cannabinoid receptor  molecular modeling  rimonabant   Functional reversal of (-)-Stepholidine analogues by replacement of benzazepine substructure using the ring-expansion strategy 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2016, 卷号: 88, 期号: 4 作者:  Li, Wei;  Zhang, Li;  Xu, Lili;  Yuan, Congmin;  Du, Peng 收藏  |  浏览/下载：7/0  |  提交时间：2019/12/05 dopamine D1 receptor  Receptor and ligands (agonist  antagonist)  selective D1R antagonists   4-Carbonyl-2,6-dibenzylidenecyclohexanone derivatives as small molecule inhibitors of STAT3 signaling pathway 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 23 作者:  Ji, Peng;  Yuan, Congmin;  Ma, Shuhua;  Fan, Junchao;  Fu, Wei 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/05 Curcumin  STAT3  Inhibitors  Antitumor  Apoptosis   Thermostability Mechanism for the Hyperthermophilicity of Extremophile Cellulase TmCel12A: Implied from Molecular Dynamics Simulation 期刊论文 JOURNAL OF PHYSICAL CHEMISTRY B, 2016, 卷号: 120, 期号: 30 作者:  Lian, Peng;  Yuan, Congmin;  Xu, Qin;  Fu, Wei 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/06 Variations of CITED2 Are Associated with Congenital Heart Disease (CHD) in Chinese Population 期刊论文 2014, 卷号: 9, 期号: 5, 页码: e98157 作者:  Liu, Yan;  Wang, Fengyu;  Wu, Yuan;  Tan, Sainan;  Wen, Qiaolian 收藏  |  浏览/下载：5/0  |  提交时间：2020/01/13