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科研机构
上海药物研究所 [8]
深圳先进技术研究院 [2]
复旦大学上海医学院 [2]
内容类型
期刊论文 [11]
会议论文 [1]
发表日期
2021 [1]
2018 [4]
2016 [1]
2015 [3]
2013 [1]
2011 [2]
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浏览/检索结果:
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PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery
期刊论文
AUTOPHAGY, 2021, 卷号: 17, 期号: 10, 页码: 2905-2922
作者:
Tang, Ying
;
Liu, Jinchang
;
Wang, Yu
;
Yang, Li
;
Han, Bing
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2022/01/04
Autophagy
functional recovery
ischemic stroke
lysophosphatidic acid receptor 5
microglial activation
poly (ADP-ribose) polymerase 14
Both Hypo-Connectivity and Hyper-Connectivity of the Insular Subregions Associated With Severity in Children With Autism Spectrum Disorders.
期刊论文
FRONTIERS IN NEUROSCIENCE, 2018
作者:
Zhou, Zhifeng
;
Gan, Yungen
;
Hu, Qingmao
;
Xu, Jinping
;
Wang, Hongwei
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/01/31
Functional connectivity of the insular sub_regions associated with severity in children with ASD
会议论文
新加坡, 2018
作者:
Qingmao Hu
;
Ziyun Xu
;
Zhenhui Zhou
;
Yungen Gan
;
Jinping Xu
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/31
Design, synthesis and biological activity of 4-(4-benzyloxy)phenoxypiperidines as selective and reversible LSD1 inhibitors
期刊论文
BIOORGANIC CHEMISTRY, 2018, 卷号: 78
作者:
Xi, Jiayue
;
Xu, Siyuan
;
Zhang, Lulu
;
Bi, Xueyuan
;
Ren, Yanshen
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
LSD1
Inhibitors
Selective
Reversible
Migration
Optimization of 5-arylidene barbiturates as potent, selective, reversible LSD1 inhibitors for the treatment of acute promyelocytic leukemia
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 17
作者:
Xu, Siyuan
;
Zhou, Chen
;
Liu, Rongfeng
;
Zhu, Qihua
;
Xu, Yungen
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
LSD1
5-Arylidene barbiturate
Selective
Reversible
Leukemia
Design, synthesis and biological evaluation of novel tetrahydroisoquinoline quaternary derivatives as peripheral kappa-opioid receptor agonists
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 13, 页码: 2964-2970
作者:
Guo, Ting
;
Gan, Zongjie
;
Chen, Jie
;
Wang, Dechuan
;
He, Ling
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Tetrahydroisoquinoline quaternary derivatives
Peripheral
kappa-Opioid receptor agonists
Fluorescent Coumarin-Artemisinin Conjugates as Mitochondria-Targeting Theranostic Probes for Enhanced Anticancer Activities
期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2015, 卷号: 21, 期号: 48, 页码: 17415-17421
作者:
Zhang, Xu
;
Ba, Qian
;
Gu, Zhanni
;
Guo, Diliang
;
Zhou, Yu
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
apoptosis
cancer
drug delivery
imaging agents
theranostic probes
novelopioidreceptoragonistmb1cohproducespotentanalgesiawithlessdepressionandsedation
期刊论文
actapharmacologicasinica, 2015, 卷号: 36, 期号: 5, 页码: 565
作者:
Zhang Lesha
;
Wang Jun
;
Chen Jianchun
;
Tao Yimin
;
Wang Yuhua
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2020/07/01
κ-opioid receptor
MB-1C-OH
(-)U50
488H
Nor-BNI
morphine
pain
acetic acid-induced writhing
formalin test
depression
sedation
Novel κ-opioid receptor agonist MB-1C-OH produces potent analgesia with less depression and sedation
期刊论文
Acta Pharmacologica Sinica, 2015, 卷号: 36, 期号: 5, 页码: 565
作者:
Zhang Lesha
;
Wang Jun
;
Chen Jianchun
;
Tao Yimin
;
Wang Yuhua
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/12/24
κ-opioid receptor
MB-1C-OH
(-)U50
488H
Nor-BNI
morphine
pain
acetic acid-induced writhing
formalin test
depression
sedation
Design, synthesis and biological evaluation of novel 4-anilinoquinazolines with C-6 urea-linked side chains as inhibitors of the epidermal growth factor receptor
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 24, 页码: 7988-7998
作者:
Zhang, Xu
;
Peng, Ting
;
Ji, Xun
;
Li, Jian
;
Tong, Linjiang
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
EGFR inhibitor
EGFR T790M/L858R
Binding mode
Irreversible EGFR inhibitor
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