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Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:
Wang, Z (Wang, Zhen)[ 1 ]
;
Jiang, XR (Jiang, Xiangrui)[ 1 ]
;
Zhang, XL (Zhang, Xianglei)[ 1,2 ]
;
Tian, GH (Tian, Guanghui)[ 3 ]
;
Yang, RL (Yang, Rulei)[ 3 ]
收藏
  |  
浏览/下载:133/0
  |  
提交时间:2019/06/28
Effective cancer immunotherapy by Ganoderma lucidum polysaccharide-gold nanocomposites through dendritic cell activation and memory T cell response
期刊论文
Carbohydrate polymers, 2019, 卷号: 205, 页码: 192-202
作者:
Zhang Shulei[1]
;
Pang Guibin[2]
;
Chen Chao[3]
;
Qin Jianzhong[4]
;
Yu Huan[5]
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浏览/下载:66/0
  |  
提交时间:2019/04/22
Cancer therapy
Dendritic cell
Immunoregulation
Nanoparticle
Polysaccharides
Geological and geochemical characteristics of the Baogudi Carlintype gold district(Southwest Guizhou, China) and their geological implications
期刊论文
2019, 卷号: 38, 期号: 4, 页码: 587-609
作者:
Songtao Li[1,2,3]
;
Yong Xia[1]
;
Jianzhong Liu[4]
;
Zhuojun Xie[1]
;
Qinping Tan[1]
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  |  
浏览/下载:30/0
  |  
提交时间:2019/12/06
Elemental
geochemistry
Fluid
inclusions
Stable
isotopes
Carlin-type
gold
deposits
Baogudi
gold
district
Southwestern
Guizhou
Geological and geochemical characteristics of the Baogudi Carlin-type gold district (Southwest Guizhou, China) and their geological implications
期刊论文
2019, 卷号: 38, 期号: 4, 页码: 587-609
作者:
Li, Songtao[1,2,3]
;
Xia, Yong[1]
;
Liu, Jianzhong[4]
;
Xie, Zhuojun[1]
;
Tan, Qinping[1]
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  |  
浏览/下载:28/0
  |  
提交时间:2019/12/06
The Efficacy and Safety of Xinmailong Injection in Patients with Chronic Heart Failure: A Multicenter Randomized Double-Blind Placebo-Controlled Trial
期刊论文
2019, 卷号: 25, 期号: 8, 页码: 856-860
作者:
Xue, Jingui[1]
;
Xu, Yong[2]
;
Deng, Yue[3]
;
Li, Fengchun[4]
;
Liu, Fan[5]
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  |  
浏览/下载:5/0
  |  
提交时间:2019/12/16
Screening and construction of a novel microbial consortium SSA-6 enriched from the gut symbionts of wood-feeding termite, Coptotermes formosanus and its biomass-based biorefineries
期刊论文
FUEL, 2019, 卷号: 236, 页码: 1128-1145
作者:
Ali, Sameh Samir[1]
;
Al-Tohamy, Rania[2]
;
Sun, Jianzhong[3]
;
Wu, Jian[4]
;
Liu Huizi[5]
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  |  
浏览/下载:11/0
  |  
提交时间:2019/12/24
Microbial consortium
Enrichment
Coptotermes formosanus
Sawdust
Biorefinery
Biomass
Pharmaceutical Potential of a Novel Chitosan Derivative Schiff Base with Special Reference to Antibacterial, Anti-Biofilm, Antioxidant, Anti-Inflammatory, Hemocompatibility and Cytotoxic Activities
期刊论文
PHARMACEUTICAL RESEARCH, 2019, 卷号: 36, 期号: 1, 页码: 5
作者:
Ali, Sameh S.[1]
;
Kenawy, El-Refaie[2]
;
Sonbol, Fatma I.[3]
;
Sun, Jianzhong[4]
;
Al-Etewy, Marwa[5]
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/24
antibacterial
antioxidant
anti-inflammatory
chitosan Schiff bases
cytotoxicity
Current advances and future perspectives of 3D printing natural-derived biopolymers
期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 207, 页码: 297-316
作者:
Liu, Jun[1]
;
Sun, Lushan[2]
;
Xu, Wenyang[3]
;
Wang, Qianqian[4]
;
Yu, Sujie[5]
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/12/24
3D printing
Additive manufacturing
Biopolymers
Biomass
Biomedical application
Unsupervised feature selection by regularized matrix factorization
期刊论文
NEUROCOMPUTING, 2018, 卷号: 273, 页码: 593-610
作者:
Qi, Miao[1]
;
Wang, Ting[1,5]
;
Liu, Fucong[1]
;
Zhang, Baoxue[3]
;
Wang, Jianzhong[1,4]
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/04/22
Dimensionality reduction
Feature selection
Matrix factorization
Sparsity and redundancy
Value of using the international classification of functioning, disability, and health for stroke rehabilitation assessment A multicenter clinical study
期刊论文
2018, 卷号: 97, 期号: 42
作者:
Zhang, Tong[1]
;
Liu, Lixu[1]
;
Xie, Rong[2]
;
Peng, Ying[3]
;
Wang, Huifang[4]
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/10
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