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科研机构
上海药物研究所 [9]
内容类型
期刊论文 [9]
发表日期
2021 [9]
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Synthesis and pharmacological evaluation of choroquine derivatives bearing long aminated side chains as antivirus and anti-inflammatory agents
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 8
作者:
Song, Zilan
;
Liu, Yuting
;
Xie, Chenghu
;
Tong, Xiankun
;
Wang, Xue
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/11/04
Choroquine
Aminochloroquine
Antivirus
Anti-inflammatory
Cytokines
Spiro ent-Clerodane Dimers: Discovery and Green Approaches for a Scalable Biomimetic Synthesis
期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 15, 页码: 5647-5651
作者:
Li, Xing-Ren
;
Yan, Bing-Chao
;
Hu, Kun
;
He, Shijun
;
Sun, Han-Dong
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/11/04
Triptolide analog LLDT-8 ameliorates psoriasis-like dermatitis in BALB/c mice via suppressing the IL-36 alpha signaling pathway
期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 169, 页码: 11
作者:
Qi, Qing
;
Li, Qian
;
Zhu, Hongwen
;
Lu, Huimin
;
Yang, Xiaoqian
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/08/17
Triptolide
LLDT-8
Psoriasis
IL-36 alpha
IL-36 alpha pathway
Inflammation
Heme supplementation ameliorates lupus nephritis through rectifying the disorder of splenocytes and alleviating renal inflammation and oxidative damage
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 94, 页码: 11
作者:
Wu, Bing
;
Wu, Yanwei
;
Fan, Chen
;
Feng, Chunlan
;
Wang, Haoyu
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2021/06/11
SLE
Lupus nephritis
Heme
Inflammation
Oxidative damage
Effects of Shuanghuanglian oral liquids on patients with COVID-19: a randomized, open-label, parallel-controlled, multicenter clinical trial
期刊论文
FRONTIERS OF MEDICINE, 2021, 页码: 14
作者:
Ni, Li
;
Wen, Zheng
;
Hu, Xiaowen
;
Tang, Wei
;
Wang, Haisheng
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2021/08/17
COVID-19
SARS-CoV-2
Shuanghuanglian oral liquid
clinical trial
Rh-Catalyzed C-H alkylation enabling modular synthesis of CF3-substituted benzannulated macrocyclic inhibitors of B cell responses dagger
期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 页码: 6
作者:
Sun, Tao
;
He, Shijun
;
Xu, Zhongliang
;
Zuo, Jianping
;
Yu, Yang
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/05/24
Marine furanocembranoids-inspired macrocycles enabled by Pd-catalyzed unactivated C(sp(3))-H olefination mediated by donor/donor carbenes
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11
作者:
Hao, Jiping
;
Guo, Xueying
;
He, Shijun
;
Xu, Zhongliang
;
Chen, Lu
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/05/24
DZ2002 alleviates psoriasis-like skin lesions via differentially regulating methylation of GATA3 and LCN2 promoters
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 91, 页码: 12
作者:
Chen, Li
;
Lin, Zemin
;
Liu, Yuting
;
Cao, Shiqi
;
Huang, Yueteng
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2021/05/24
DZ2002
Psoriasis
DNA methylation
Keratinocyte
Inflammatory infiltration
Artemisinin analogue SM934 protects against lupus-associated antiphospholipid syndrome via activation of Nrf2 and its targets
期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2021, 页码: 18
作者:
Lin, Zemin
;
Liu, Yuting
;
Chen, Li
;
Cao, Shiqi
;
Huang, Yueteng
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
artemisinin analog
antiphospholipid syndrome
antiphospholipid syndrome nephropathy associated lupus nephritis
oxidative stress
inflammation
Nrf2
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