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上海药物研究所 [8]
中国医学科学院 北京... [3]
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期刊论文 [18]
发表日期
2019 [18]
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DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models
期刊论文
ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 期号: 1, 页码: 15
作者:
Zhang, Zongwang
;
Wu, Yanwei
;
Wu, Bing
;
Qi, Qing
;
Li, Heng
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Systemic sclerosis
SAHH inhibitor
Fibrosis
Inflammation
Vasculopathy
TGF-beta
CNOT2 facilitates dengue virus infection via negatively modulating IFN-Independent Non-Canonical JAK/STAT pathway
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 515, 期号: 3, 页码: 403-409
作者:
Liu, Jianan
;
Yang, Li
;
Liu, Feifei
;
Li, Heng
;
Tang, Wei
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  |  
浏览/下载:56/0
  |  
提交时间:2020/07/01
CNOT2
Dengue virus
IFN
JAK-STAT pathway
ISGs
Inhibition of phosphodiesterase-4 attenuates murine ulcerative colitis through interference with mucosal immunity
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2209-2226
作者:
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  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
Treatment of Chronic Hepatitis B Virus Infection Using Small Molecule Modulators of Nucleocapsid Assembly: Recent Advances and Perspectives
期刊论文
ACS INFECTIOUS DISEASES, 2019, 卷号: 5, 期号: 5, 页码: 713-724
作者:
Yang, Li
;
Liu, Feifei
;
Tong, Xiankun
;
Hoffmann, Daniel
;
Zuo, Jianping
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  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
hepatitis B virus
HBV core protein
HBcAg
capsid assembly
capsid assembly modulators (CAMs)
antiviral therapy
clinical trials
Assay development for determination of DZ2002, a new reversible SAHH inhibitor, and its acid metabolite DZA in blood and application to rat pharmacokinetic study
期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2019, 卷号: 9, 期号: 1, 页码: 25-33
作者:
Jia, Weiwei
;
Li, Jing
;
Du, Feifei
;
Sun, Yan
;
Xu, Fang
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  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
S-adenosyl-L-homocysteine hydrolase
DZ2002
Carboxylesterases
Pharmacokinetics
Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal -actinin-4 expression and stabilizing integrin-cytoskeleton linkage
期刊论文
ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 页码: 16
作者:
He, Shijun
;
Liu, Xing
;
Lin, Zemin
;
Liu, Yuting
;
Gu, Lei
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/07/01
SAHH inhibitor
Lupus nephritis
-Actinin-4
Integrin-linked kinase
Integrin
Focal adhesion
Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal α-actinin-4 expression and stabilizing integrin-cytoskeleton linkage
期刊论文
Arthritis Research & Therapy, 2019, 卷号: 21, 期号: 1
作者:
He,Shijun
;
Liu,Xing
;
Lin,Zemin
;
Liu,Yuting
;
Gu,Lei
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2020/07/01
SAHH inhibitor
Lupus nephritis
α-Actinin-4
Integrin-linked kinase
Integrin
Focal adhesion
The development of Yangshao agriculture and its interaction with social dynamics in the middle Yellow River region, China
期刊论文
HOLOCENE, 2019, 卷号: 29, 期号: 1, 页码: 173-180
作者:
Wang, Can
;
Lu, Houyuan
;
Gu, Wanfa
;
Wu, Naiqin
;
Zhang, Jianping
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  |  
浏览/下载:103/0
  |  
提交时间:2019/03/04
agriculture
China
millets
phytolith analysis
rice cultivation
Yangshao culture
Combined immunosuppressive treatment (CIST) in lupus nephritis: a multicenter, randomized controlled study
期刊论文
CLINICAL RHEUMATOLOGY, 2019, 卷号: 38, 期号: 4
作者:
Lin, Jin
;
An, Yuan
;
Zhou, Yunshan
;
Bi, Liqi
;
Liu, Bo
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  |  
浏览/下载:45/0
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提交时间:2019/12/05
Immunosuppressive agents
Lupus nephritis
Remission inducing
Systemic lupus erythematosus
Assay development for determination of DZ2002, a new reversible SAHH inhibitor, and its acid metabolite DZA in blood and application to rat pharmacokinetic study
期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2019, 卷号: 9, 期号: 1
作者:
Li, Chuan
;
Olaleye, Olajide E.
;
Chen, Danghui
;
Tang, Wei
;
Zuo, Jianping
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/12/05
S-adenosyl-L-homocysteine hydrolase
DZ2002
Carboxylesterases
Pharmacokinetics
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