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CORC

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Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090
作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan
收藏  |  浏览/下载：22/0  |  提交时间：2022/01/04
Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14822-14847
作者:  Wei, Dan;  Wang, Hanlin;  Zeng, Qinghe;  Wang, Wenjing;  Hao, Bingbing
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16
Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong
收藏  |  浏览/下载：17/0  |  提交时间：2021/12/16
Design, Synthesis, and Biological Evaluation of Orally Bioavailable CHK1 Inhibitors Active against Acute Myeloid Leukemia 期刊论文
CHEMMEDCHEM, 2021, 页码: 12
作者:  Jin, Tingting;  Wang, Peipei;  Long, Xiubing;  Jiang, Kailong;  Song, Pinrao
收藏  |  浏览/下载：133/0  |  提交时间：2021/05/24
Pd-Catalyzed Decarboxylative Olefination: Stereoselective Synthesis of Polysubstituted Butadienes and Macrocyclic P-glycoprotein Inhibitors 期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, 卷号: 142, 期号: 22, 页码: 9982-9992
作者:  Song, Bichao;  Xie, Peipei;  Li, Yingzi;  Hao, Jiping;  Wang, Lu
收藏  |  浏览/下载：22/0  |  提交时间：2020/12/24
Discovery of a 2-pyridinyl urea-containing compound YD57 as a potent inhibitor of apoptosis signal-regulating kinase 1 (ASK1) 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 195, 页码: 13
作者:  Zhang, Shiyan;  Huang, Chaoying;  Lyu, Xilin;  Wang, Peipei;  Zang, Yi
收藏  |  浏览/下载：39/0  |  提交时间：2020/07/01
A galactoglucan isolated from of Cistanche deserticola Y. C. Ma. and its bioactivity on intestinal bacteria strains 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 223, 页码: 8
作者:  Zeng, Hui;  Huang, Lulin;  Zhou, Lishuang;  Wang, Peipei;  Chen, Xia
收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01
Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino) pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 173, 页码: 44-62
作者:  Tong, Lexian;  Song, Pinrao;  Jiang, Kailong;  Xu, Lei;  Jin, Tingting
收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01
Discovery of 1,3-diphenyl-1H-pyrazole derivatives containing rhodanine-3-alkanoic acid groups as potential PTP1B inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 10, 页码: 1187-1193
作者:  Sun, Liangpeng;  Wang, Peipei;  Xu, Lili;  Gao, Lixin;  Li, Jia
收藏  |  浏览/下载：4/0  |  提交时间：2020/07/01
HH1-1, a novel Galectin-3 inhibitor, exerts anti-pancreatic cancer activity by blocking Galectin-3/EGFR/AKT/FOXO3 signaling pathway 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 204, 页码: 111-123
作者:  Yao, Yanli;  Zhou, Lishuang;  Liao, Wenfeng;  Chen, Huanjun;  Du, Zhenyun
收藏  |  浏览/下载：140/0  |  提交时间：2019/01/08

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