QQ客服 官方微博 反馈留言

浏览/检索结果: 共15条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Zhang, Qing;  Chen, Lin-hai;  Yang, Hui;  Fang, You-chen;  Wang, Si-wei 收藏  |  浏览/下载：45/0  |  提交时间：2022/01/18 GPR84  medium chain fatty acid receptor  GPCR  inflammatory bowel diseases  ulcerative colitis  NLRP3 inflammasome  macrophages   CsCCD2 Access Tunnel Design for a Broader Substrate Profile in Crocetin Production 期刊论文 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 39, 页码: 11626-11636 作者:  Liang, Nan;  Yao, Ming-Dong;  Wang, Ying;  Liu, Jia;  Feng, Lu 收藏  |  浏览/下载：20/0  |  提交时间：2021/12/01 crocetin  CCD2  access tunnel engineering  Saccharomyces cerevisiae   Identification of Betulinic Acid Derivatives as Potent TGR5 Agonists with Antidiabetic Effects via Humanized TGR5(H88Y) Mutant Mice 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12181-12199 作者:  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Liang, Xiaoying;  Lan, Yuan 收藏  |  浏览/下载：40/0  |  提交时间：2021/11/04 ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker 期刊论文 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 9 作者:  Chen, Yuning;  Zhang, Ya-Nan;  Yan, Renhong;  Wang, Guifeng;  Zhang, Yuanyuan 收藏  |  浏览/下载：65/0  |  提交时间：2021/11/04 Structural insights into ligand recognition and activation of the melanocortin-4 receptor 期刊论文 CELL RESEARCH, 2021, 页码: 13 作者:  Zhang, Huibing;  Chen, Li-Nan;  Yang, Dehua;  Mao, Chunyou;  Shen, Qingya 收藏  |  浏览/下载：33/0  |  提交时间：2021/11/04 Facing small and biased data dilemma in drug discovery with enhanced federated learning approaches 期刊论文 SCIENCE CHINA-LIFE SCIENCES, 2021, 页码: 11 作者:  Xiong, Zhaoping;  Cheng, Ziqiang;  Lin, Xinyuan;  Xu, Chi;  Liu, Xiaohong 收藏  |  浏览/下载：43/0  |  提交时间：2021/11/04 federated learning  drug discovery  FedAMP  Non-IID data   Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor 期刊论文 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11 作者:  Cong, Zhaotong;  Chen, Li-Nan;  Ma, Honglei;  Zhou, Qingtong;  Zou, Xinyu 收藏  |  浏览/下载：45/0  |  提交时间：2021/08/17 Strigolactone mimic 2-nitrodebranone is highly active in Arabidopsis growth and development 期刊论文 PLANT JOURNAL, 2021, 页码: 10 作者:  Li, Suhua;  Li, Yuwen;  Chen, Linhai;  Zhang, Chi;  Wang, Fei 收藏  |  浏览/下载：42/0  |  提交时间：2021/08/17 Phytohormone  GR24  2NOD  Signaling Pathway  Plant growth regulator   Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsule 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 18 作者:  Lan, Xiao-fang;  Olaleye, Olajide E.;  Lu, Jun-lan;  Yang, Wei;  Du, Fei-fei 收藏  |  浏览/下载：73/0  |  提交时间：2021/06/11 LianhuaQingwen  glycyrrhetic acid  24-hydroxyglycyrrhetic acid  Gancao-induced pseudoaldosteronism  licorice-induced pseudoaldosteronism  11β  -hydroxysteroid dehydrogenase 2  COVID-19  colonic microbiota   Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 216, 页码: 20 作者:  Gao, Dingding;  Jin, Nan;  Fu, Yixian;  Zhu, Yueyue;  Wang, Yujie 收藏  |  浏览/下载：42/0  |  提交时间：2021/06/11 STAT3 signaling pathway  Benzothiazole  Rational design  Antitumor activity  Molecular docking