Strigolactone mimic 2-nitrodebranone is highly active in Arabidopsis growth and development

doi:10.1111/tpj.15274

	Strigolactone mimic 2-nitrodebranone is highly active in Arabidopsis growth and development
	Li, Suhua 1,2; Li, Yuwen 2; Chen, Linhai 3; Zhang, Chi 1; Wang, Fei 2; Li, Haiou 2,4; Wang, Ming 5; Wang, Yupei 2; Nan, Fajun 3; Xie, Daoxin 2
刊名	PLANT JOURNAL
	2021-05-22
页码	10
关键词	Phytohormone GR24 2NOD Signaling Pathway Plant growth regulator
ISSN号	0960-7412
DOI	10.1111/tpj.15274
通讯作者	Nan, Fajun(fjnan@simm.ac.cn) ; Xie, Daoxin(daoxinlab@tsinghua.edu.cn) ; Yan, Jianbin(jianbinlab@caas.cn)
英文摘要	Strigolactones play crucial roles in regulating plant architecture and development, as endogenous hormones, and orchestrating symbiotic interactions with fungi and parasitic plants, as components of root exudates. rac-GR24 is currently the most widely used strigolactone analog and serves as a reference compound in investigating the action of strigolactones. In this study, we evaluated a suite of debranones and found that 2-nitrodebranone (2NOD) exhibited higher biological activity than rac-GR24 in various aspects of plant growth and development in Arabidopsis, including hypocotyl elongation inhibition, root hair promotion and senescence acceleration. The enhanced activity of 2NOD in promoting AtD14-SMXL7 and AtD14-MAX2 interactions indicates that the molecular structure of 2NOD is a better match for the ligand perception site pocket of D14. Moreover, 2NOD showed lower activity than rac-GR24 in promoting Orobanche cumana seed germination, suggesting its higher ability to control plant architecture than parasitic interactions. In combination with the improved stability of 2NOD, these results demonstrate that 2NOD is a strigolactone analog that can specifically mimic the activity of strigolactones and that 2NOD exhibits strong potential as a tool for studying the strigolactone signaling pathway in plants.
资助项目	National Key R&D Program of China[2020YFA0907900] ; National Key R&D Program of China[2016YFA0500500] ; Fundamental Research Funds for Central Nonprofit Scientific Institution[Y2020XK23] ; Elite Young Scientists Program of CAAS ; Agricultural Science and Technology Innovation Program ; Youth Innovation Promotion Association of the Chinese Academy of Sciences[2017329]
WOS关键词	F-BOX PROTEIN ; STRIGA-HERMONTHICA ; GERMINATION STIMULANTS ; HORMONE-RECEPTOR ; PLANT HORMONES ; INHIBITION ; RICE ; RESPONSES ; ACTS ; STEREOISOMERS
WOS研究方向	Plant Sciences
语种	英语
出版者	WILEY
WOS记录号	WOS:000652834600001
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/297373]
专题	中国科学院上海药物研究所
通讯作者	Nan, Fajun; Xie, Daoxin; Yan, Jianbin
作者单位	1.Chinese Acad Agr Sci, Agr Genom Inst Shenzhen,Minist Agr, Shenzhen Key Lab Agr Synthet Biol,Genome Anal Lab, Guangdong Lab Lingnan Modern Agr,Shenzhen Branch, Shenzhen 518124, Peoples R China 2.Tsinghua Univ, Sch Life Sci, Tsinghua Peking Ctr Life Sci, MOE Key Lab Bioinformat, Beijing 100084, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China 4.Hunan Agr Univ, Coll Biosci & Biotechnol, Hunan Prov Key Lab Phytohormones & Growth Dev, Changsha 410128, Peoples R China 5.Nanjing Agr Univ, Dept Plant Pathol, Nanjing 210000, Peoples R China
推荐引用方式 GB/T 7714	Li, Suhua,Li, Yuwen,Chen, Linhai,et al. Strigolactone mimic 2-nitrodebranone is highly active in Arabidopsis growth and development[J]. PLANT JOURNAL,2021:10.
APA	Li, Suhua.,Li, Yuwen.,Chen, Linhai.,Zhang, Chi.,Wang, Fei.,...&Yan, Jianbin.(2021).Strigolactone mimic 2-nitrodebranone is highly active in Arabidopsis growth and development.PLANT JOURNAL,10.
MLA	Li, Suhua,et al."Strigolactone mimic 2-nitrodebranone is highly active in Arabidopsis growth and development".PLANT JOURNAL (2021):10.