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科研机构
上海药物研究所 [162]
内容类型
期刊论文 [162]
发表日期
2020 [162]
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浏览/检索结果:
共162条,第1-10条
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发表日期:2020
专题:上海药物研究所
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Gigantol ameliorates CCl4-induced liver injury via preventing activation of JNK/cPLA2/12-LOX inflammatory pathway
期刊论文
SCIENTIFIC REPORTS, 2020, 卷号: 10, 期号: 1, 页码: 13
作者:
Xue, Yaru
;
Deng, Qiangqiang
;
Zhang, Qingli
;
Ma, Zhenghua
;
Chen, Binfan
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
Combinatorial Photothermal 3D-Printing Scaffold and Checkpoint Blockade Inhibits Growth/Metastasis of Breast Cancer to Bone and Accelerates Osteogenesis
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 14
作者:
He, Chao
;
Yu, Luodan
;
Yao, Heliang
;
Chen, Yu
;
Hao, Yongqiang
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/05/24
bone metastasis
breast cancer
checkpoint blockade
immunotherapy
osteogenesis
photothermal therapy
Diphyllin Improves High-Fat Diet-Induced Obesity in Mice Through Brown and Beige Adipocytes
期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2020, 卷号: 11, 页码: 13
作者:
Duan, Ya-Nan
;
Ge, Xiang
;
Jiang, Hao-Wen
;
Zhang, Hong-Jie
;
Zhao, Yu
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/05/24
diphyllin
obesity
brown adipocyte
differentiation
thermogenesis
V-ATPase
Large-scale Generation of Functional and Transplantable Hepatocytes and Cholangiocytes from Human Endoderm Stem Cells
期刊论文
CELL REPORTS, 2020, 卷号: 33, 期号: 10, 页码: 24
作者:
Feng, Sisi
;
Wu, Jiaying
;
Qiu, Wei-Lin
;
Yang, Li
;
Deng, Xiaogang
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/05/24
DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Dai, Meng-di
;
Wang, Yue-liang
;
Fan, Jun
;
Dai, Yang
;
Ji, Yin-chun
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/05/24
receptor tyrosine kinase
FGFR inhibitor
DW14383
antitumor activity
1-Phenyl-N-(benzothiazol-2-yl)methanimine derivatives as Middle East respiratory syndrome coronavirus inhibitors
期刊论文
RSC ADVANCES, 2020, 卷号: 10, 期号: 71, 页码: 43299-43311
作者:
Hu, Min-Qi
;
Li, Heng
;
Lin, Ying
;
Zhang, Ying
;
Tang, Jie
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/05/24
Determination of the antidiabetic chemical basis of Phellodendri Chinensis Cortex by integrating hepatic disposition in vivo and hepatic gluconeogenese inhibition in vitro
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 263, 页码: 10
作者:
Tian, Xiaoting
;
Xu, Zhou
;
Hu, Pei
;
Yu, Yanyan
;
Li, Zhixiong
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2020/12/21
Phellodendri Chinensis cortex
Hepatic disposition
Pharmacokinetics
Berberine
Metabolites
Hepatic gluconeogenesis
Meroterpenoids with diverse structures and anti-inflammatory activities from Rhododendron anthopogonoides
期刊论文
PHYTOCHEMISTRY, 2020, 卷号: 180, 页码: 11
作者:
Shi, Qing
;
Li, Teng-Teng
;
Wu, Yong-Mei
;
Sun, Xin-Yu
;
Lei, Chun
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/12/24
Rhododendron anthopogonoides Maxim
Ericaceae
Meroterpenoids
Anthoponoids A-I
Daurichromene D
Anti-inflammation
Liquid chromatography-tandem mass spectrometric assay for TPN171 in human plasma
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 191, 页码: 8
作者:
Zhang, Mengqi
;
Liu, Haiming
;
He, Jiajin
;
Gui, Yuzhou
;
Qian, Hongjie
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/24
TPN171
LC-MS/MS
Human plasma
Protein precipitation
Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yu, Ming-cheng
;
Yang, Feng
;
Ding, Xiao-yu
;
Sun, Nan-nan
;
Jiang, Zheng-yuan
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2020/12/24
RORγ
t
cocrystal structures
MD simulation
“
short”
inverse agonists
agonists
“
long”
inverse agonists
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