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科研机构
上海药物研究所 [29]
内容类型
期刊论文 [28]
会议论文 [1]
发表日期
2021 [1]
2020 [4]
2019 [3]
2018 [1]
2017 [4]
2016 [2]
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Development of a nanobody-based immunoassay for the sensitive detection of fibrinogen-like protein 1
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhang, Wan-ting
;
Liu, Ting-ting
;
Wu, Man
;
Chen, Xiao-chen
;
Han, Li
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/05/24
nanobody
FGL1
cancer immunology
diagnosis
immune checkpoint
Investigation of the remote acyl group participation in glycosylation from conformational perspectives by using trichloroacetimidate as the acetyl surrogate
期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2020, 卷号: 7, 期号: 13, 页码: 1606-1615
作者:
Xu, Ke
;
Man, Qingmin
;
Zhang, Yang
;
Guo, Jia
;
Liu, Yichu
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/12/24
Design, Synthesis, and Biological Evaluation of 8-Mercapto-3,7-Dihydro-1H-Purine-2,6-Diones as Potent Inhibitors of SIRT1, SIRT2, SIRT3, and SIRT5
期刊论文
MOLECULES, 2020, 卷号: 25, 期号: 12, 页码: 18
作者:
Han, Haozhen
;
Li, Chunpu
;
Li, Man
;
Yang, Lisheng
;
Zhao, Sen
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/12/24
sirtuins
inhibitor
structure-activity relationship
deacetylase
Cycloastragenol upregulates SIRT1 expression, attenuates apoptosis and suppresses neuroinflammation after brain ischemia
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Li, Man
;
Li, Shi-chun
;
Dou, Bao-kai
;
Zou, Ying-xiang
;
Han, Hao-zhen
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
cycloastragenol
SIRT1
apoptosis
neuroinflammation
cerebral ischemia
Peptidyl-Lys metalloendopeptidase (Lys-N) purified from dry fruit of Grifola frondosa demonstrates "mirror"digestion property with lysyl endopeptidase (Lys-C)
期刊论文
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2020, 卷号: 34, 期号: 2, 页码: 11
作者:
Zhao, Mingzhi
;
Hao, Bingbing
;
Li, Honghao
;
Cai, Man
;
Xie, Jingjing
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Exploration of the structure-activity relationship and druggability of novel oxazolidinone-based compounds as Gram-negative antibacterial agents
期刊论文
ARCHIV DER PHARMAZIE, 2019, 页码: 13
作者:
Ding, Shi
;
Ji, Jing-Chao
;
Zhang, Ming-Juan
;
Yang, Yu-She
;
Wang, Rui
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
antibacterial activity
oxazolidine
QSAR
Ligand-induced activation of ERK1/2 signaling by constitutively active G(s)-coupled 5-HT receptors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1157-1167
作者:
Liu, Ping
;
Yin, Yu-ling
;
Wang, Ting
;
Hou, Li
;
Wang, Xiao-xi
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
5-HT4R
5-HT6R
5-HT7AR
5-HT
ERK1/2
G(s)
beta-arrestin
Fyn
Src
Xanthatin inhibits STAT3 and NF-kappa B signalling by covalently binding to JAK and IKK kinases
期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 卷号: 23, 期号: 6, 页码: 4301-4312
作者:
Liu, Man
;
Xiao, Cheng-qian
;
Sun, Ming-wei
;
Tan, Min-jia
;
Hu, Li-hong
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/07/01
covalent interaction
IKK inhibitor
JAK inhibitor
natural compound
Targeting AKT with Oridonin Inhibits Growth of Esophageal Squamous Cell Carcinoma In Vitro and Patient-Derived Xenografts In Vivo
期刊论文
MOLECULAR CANCER THERAPEUTICS, 2018, 卷号: 17, 期号: 7, 页码: 1540-1553
作者:
Song, Mengqiu
;
Liu, Xuejiao
;
Liu, Kangdong
;
Zhao, Ran
;
Huang, Hai
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/01/08
Critical Role of Hepatic Cyp450 sin the Testis-Specific Toxicity of (5R)-5-Hydroxytriptolide in C57BL/6 Mice
期刊论文
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8
作者:
Yu, Cunzhi
;
Li, Yu
;
Liu, Mingxia
;
Gao, Man
;
Li, Chenggang
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/01/08
(5R)-5-hydroxytriptolide
functional knockout
cytochrome P450
testes
gamma-H2AX
RNA polymerase II
androgen receptor
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