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Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma 期刊论文
NATURE MEDICINE, 2016, 卷号: 22, 期号: 3, 页码: 270-277
Ambrogio, Chiara; Gomez-Lopez, Gonzalo; Falcone, Mattia; Vidal, August; Nadal, Ernest; Crosetto, Nicola; Blasco, Rafael B.; Fernandez-Marcos, Pablo J.; Sanchez-Cespedes, Montserrat; Ren, Xiaomei; Wang, Zhen; Ding, Ke; Hidalgo, Manuel; Serrano, Manuel; Villanueva, Alberto; Santamaria, David; Barbacid, Mariano
收藏  |  浏览/下载：32/0  |  提交时间：2016/12/16
Structure-Based Design of Tetrahydroisoquinoline-7-carboxamides as Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 12, 页码: 5911-5916
Wang, Zhen; Bian, Huan; Bartual, Sergio G.; Du, Wenting; Luo, Jinfeng; Zhao, Hu; Zhang, Shasha; Mo, Cheng; Zhou, Yang; Xu, Yong; Tu, Zhengchao; Ren, Xiaomei; Lu, Xiaoyun; Brekken, Rolf A.; Yao, Libo; Bullock, Alex N.; Su, Jin; Ding, Ke
收藏  |  浏览/下载：50/0  |  提交时间：2016/12/16
Genetically humanized pigs exclusively expressing human insulin are generated through custom endonuclease-mediated seamless engineering 期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2016, 卷号: 8, 期号: 2, 页码: 174-177
作者:  Wu, Han;  Lai, Liangxue;  Li, Xiaoping;  Sun, Xiaofang;  Fan, Yong
收藏  |  浏览/下载：30/0  |  提交时间：2018/12/13
Nanofibrous asymmetric membranes self-organized from chemically heterogeneous electrospun mats for skin tissue engineering 期刊论文
BIOMEDICAL MATERIALS, 2016, 卷号: 11, 期号: 3
作者:  Xin, Yanjiao;  Wu, Chaoxi;  Chen, Tian;  Zhang, Zhen;  Ren, Zhe
收藏  |  浏览/下载：23/0  |  提交时间：2018/12/13
Asteltoxins with Antiviral Activities from the Marine Sponge-Derived Fungus Aspergillus sp SCSIO XWS02F40 期刊论文
MOLECULES, 2016, 卷号: 21, 期号: 1
作者:  Zhou, Xue-Feng;  Wang, Zhen;  Lin, Xiu-Ping;  Tian, Yong-Qi;  Liu, Yonghong
收藏  |  浏览/下载：15/0  |  提交时间：2018/12/13
Structure-Based Design of Tetrahydroisoquinoline-7-carboxamides as Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 12, 页码: 5911-5916
作者:  Yao, Libo;  Ding, Ke;  Su, Jin;  Bullock, Alex N.;  Brekken, Rolf A.
收藏  |  浏览/下载：32/0  |  提交时间：2018/12/13
Discovery of Benzo[cd]indol-2(1H)-ones as Potent and Specific BET Bromodomain Inhibitors: Structure-Based Virtual Screening, Optimization, and Biological Evaluation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 4, 页码: 1565-1579
作者:  Tu, Zhengchao;  Zhou, Yulai;  Ding, Ke;  Xu, Yong;  Xue, Xiaoqian
收藏  |  浏览/下载：25/0  |  提交时间：2018/12/13
Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma 期刊论文
NATURE MEDICINE, 2016, 卷号: 22, 期号: 3, 页码: 270-277
作者:  Villanueva, Alberto;  Santamaria, David;  Barbacid, Mariano;  Nadal, Ernest;  Crosetto, Nicola
收藏  |  浏览/下载：25/0  |  提交时间：2018/12/13
Design, synthesis and cytotoxic activities of novel 2,5-diketopiperazine derivatives 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 121, 页码: 500-509
作者:  Tu, Zheng-Chao;  Liao, Sheng-Rong;  Qin, Xiao-Chu;  Wang, Zhen;  Li, Ding
收藏  |  浏览/下载：14/0  |  提交时间：2018/12/13
Discovery of Benzo[cd]indol-2(1H)-ones as Potent and Specific BET Bromodomain Inhibitors: Structure-Based Virtual Screening, Optimization, and Biological Evaluation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 4, 页码: 1565-1579
Xue, Xiaoqian; Zhang, Yan; Liu, Zhaoxuan; Song, Ming; Xing, Yanli; Xiang, Qiuping; Wang, Zhen; Tu, Zhengchao; Zhou, Yulai; Ding, Ke; Xu, Yong
收藏  |  浏览/下载：20/0  |  提交时间：2016/12/16

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