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科研机构
上海药物研究所 [159]
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期刊论文 [149]
会议论文 [6]
学位论文 [4]
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2021 [3]
2020 [10]
2019 [4]
2018 [16]
2017 [7]
2016 [13]
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Enzyme-Activated Prodrug-Based Smart Liposomes Specifically Enhance Tumor Hemoperfusion with Efficient Drug Delivery to Pancreatic Cancer Cells and Stellate Cells
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2021, 页码: 14
作者:
Duan, Nianxiu
;
Li, Junjun
;
Song, Sha
;
Wang, Feng
;
Yang, Yiwei
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/11/04
drug delivery
pancreatic cancer
prodrugs
smart liposomes
tumor-specific vascular promotion
Metal-drug nanoparticles-mediated osteolytic microenvironment regulation for enhanced radiotherapy of orthotopic osteosarcoma
期刊论文
CHEMICAL ENGINEERING JOURNAL, 2021, 卷号: 417, 页码: 11
作者:
Geng, Huan
;
Zhou, Mengxue
;
Li, Bin
;
Liu, Liang
;
Yang, Xu
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/17
Metal-drug nanoparticles
Orthotopic osteosarcoma
Osteolytic microenvironment
Zoledronate
Radiotherapy
Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells
期刊论文
THORACIC CANCER, 2021, 页码: 9
作者:
Zhang, Mi
;
Quan, Haitian
;
Fu, Li
;
Li, Yun
;
Fu, Haoyu
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/05/24
EGFR‐
mutant non‐
small cell lung cancer
famitinib
HS‐
10296
multi‐
targeted tyrosine kinase inhibitor
third‐
generation EGFR inhibitor
Deformable liposomal codelivery of vorinostat and simvastatin promotes antitumor responses through remodeling tumor microenvironment
期刊论文
BIOMATERIALS SCIENCE, 2020, 卷号: 8, 期号: 24, 页码: 7166-7176
作者:
Tu, Bin
;
He, Yang
;
Chen, Binfan
;
Wang, Yonghui
;
Gao, Yanrong
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2021/05/24
DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Dai, Meng-di
;
Wang, Yue-liang
;
Fan, Jun
;
Dai, Yang
;
Ji, Yin-chun
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/05/24
receptor tyrosine kinase
FGFR inhibitor
DW14383
antitumor activity
DCZ3301, an aryl-guanidino agent, inhibits ocular neovascularization via PI3K/AKT and ERK1/2 signaling pathways
期刊论文
EXPERIMENTAL EYE RESEARCH, 2020, 卷号: 201, 页码: 8
作者:
Xu, Kai
;
Li, Bo
;
Zhang, Shujie
;
Hu, Fangyuan
;
Xu, Zhijian
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
DCZ3301
Apoptosis
PI3K/AKT pathway
ERK1/2 pathway
Choroid microvascular sprouting
Corneal neovascularization
Phospholipid membrane-decorated deep-penetrated nanocatalase relieve tumor hypoxia to enhance chemo-photodynamic therapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 11, 页码: 2246-2257
作者:
Yin, Junjing
;
Cao, Haiqiang
;
Wang, Hong
;
Sun, Kaoxiang
;
Li, Yaping
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/05/24
Photodynamic therapy
Tumor hypoxia
Catalase
Tumor penetration
Drug delivery
Nanoparticle
Tumor targeting
Cancer metastasis
Cancer therapy
Metabolic modulation via mTOR pathway and anti-angiogenesis remodels tumor microenvironment using PD-L1-targeting codelivery
期刊论文
BIOMATERIALS, 2020, 卷号: 255, 页码: 12
作者:
Chen, Binfan
;
Gao, Ang
;
Tu, Bin
;
Wang, Yonghui
;
Yu, Xiaolu
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/24
Tumor-associated macrophage
Glycolysis
mTOR
Angiogenesis
Tumor immune microenvironment
Liposome
Emerging roles of class I PI3K inhibitors in modulating tumor microenvironment and immunity
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Sun, Pu
;
Meng, Ling-hua
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/12/21
phosphoinositide 3-kinase (PI3K)
PI3K inhibitors
tumor microenvironment
immune cells
immunotherapy
Corn silk crude polysaccharide exerts anti-pancreatic cancer activity by blocking the EGFR/PI3K/AKT/CREB signaling pathway
期刊论文
FOOD & FUNCTION, 2020, 卷号: 11, 期号: 8, 页码: 6961-6970
作者:
Tao, Hong
;
Chen, Xia
;
Du, Zhenyun
;
Ding, Kan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/24
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